Catalog No.
YHD39201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp11-Gly181
Predicted molecular weight
21.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20338
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Rab-4A, RAB4A, RAB4
RAB4B and Japanese encephalitis virus E protein interaction is essential for viral entry in early endosomes., PMID:40020812
Legionella uses host Rab GTPases and BAP31 to create a unique ER niche., PMID:39661521
Deciphering the role of lipid metabolism-related genes in Alzheimer's disease: a machine learning approach integrating Traditional Chinese Medicine., PMID:39507054
RAB4A is a master regulator of cancer cell stemness upstream of NUMB-NOTCH signaling., PMID:39463384
Rab4b Promotes Cytolethal Distending Toxin from Glaesserella parasuis-Induced Cytotoxicity in PK-15 Cells., PMID:39330865
Arf1-dependent LRBA recruitment to Rab4 endosomes is required for endolysosome homeostasis., PMID:39325073
Generation of RAB4A homozygous knockout induced pluripotent stem cell (iPSC) line., PMID:39299131
Ras-related Protein in Brain 4A (Rab4A) is Downregulated by miR-496 to inhibit the Progression of Gastric Cancer., PMID:38523522
Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation., PMID:38519468
Endolysosomal trafficking controls yolk granule biogenesis in vitellogenic Drosophila oocytes., PMID:38315726
A Rab39-Klp98A-Rab35 endocytic recycling pathway is essential for rapid Golgi-dependent furrow ingression., PMID:37590130
Receptor-mediated internalization promotes increased endosome size and number in a RAB4- and RAB5-dependent manner., PMID:37423034
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families., PMID:37232246
Ligand-dependent intracellular trafficking of the G protein-coupled P2Y6 receptor., PMID:37059189
KDEL Receptor Trafficking to the Plasma Membrane Is Regulated by ACBD3 and Rab4A-GTP., PMID:37048152
A Rab10-ACAP1-Arf6 GTPases cascade modulates M4 muscarinic acetylcholine receptor trafficking and signaling., PMID:36917255
Role of SNPs located in the exon 9 of ATAPA1 gene on goose egg production., PMID:36774712
RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation., PMID:36307864
RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes., PMID:36282215
TFG regulates secretory and endosomal sorting pathways in neurons to promote their activity and maintenance., PMID:36161950
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer., PMID:36129611
Involvement of Rab11 in osteoblastic differentiation: Its up-regulation during the differentiation and by tensile stress., PMID:35932574
The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes., PMID:35753407
Cell type-specific mechanistic target of rapamycin-dependent distortion of autophagy pathways in lupus nephritis., PMID:35288362
Ras-related proteins (Rab) play significant roles in sperm motility and capacitation status., PMID:35180576
Direct interaction between Rab5a and Rab4a enhanced epidermal growth factor-stimulated proliferation of gastric cancer cells., PMID:34721780
Exploring the role of the multiple sclerosis susceptibility gene CLEC16A in T cells., PMID:34643957
Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264 Macrophages., PMID:34135890
Opposing functions for retromer and Rab11 in extracellular vesicle traffic at presynaptic terminals., PMID:34019080
Intracellular trafficking of Notch orchestrates temporal dynamics of Notch activity in the fly brain., PMID:33828096
A conserved haplotype in Wagyu cattle contains RAB4A whose encoded protein regulates glucose trafficking in muscle and fat cells., PMID:33709423
β-Adrenergic control of sarcolemmal CaV1.2 abundance by small GTPase Rab proteins., PMID:33558236
A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance., PMID:33420373
Membrane Tethering Potency of Rab-Family Small GTPases Is Defined by the C-Terminal Hypervariable Regions., PMID:33102484
Serotonin stimulated parathyroid hormone related protein induction in the mammary epithelia by transglutaminase-dependent serotonylation., PMID:33095824
Effect of docosahexaenoic acid, phorbol myristate acetate, and insulin on the interaction of the FFA4 (short isoform) receptor with Rab proteins., PMID:32986985
Agonist-activated glucagon receptors are deubiquitinated at early endosomes by two distinct deubiquitinases to facilitate Rab4a-dependent recycling., PMID:32967969
UNC0321 inhibits high glucose induced apoptosis in HUVEC by targeting Rab4., PMID:32877824
The atypical Rho GTPase RhoU interacts with intersectin-2 to regulate endosomal recycling pathways., PMID:32737221
Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations., PMID:32709066
Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington's disease., PMID:32611447
Efficient entry of budded virions of Autographa californica multiple nucleopolyhedrovirus into Spodoptera frugiperda cells is dependent on dynamin, Rab5, and Rab11., PMID:32417416
GGA3 interacts with L-type prostaglandin D synthase and regulates the recycling and signaling of the DP1 receptor for prostaglandin D2 in a Rab4-dependent mechanism., PMID:32334026
Complex Rab4-Mediated Regulation of Endosomal Size and EGFR Activation., PMID:32019812
Membrane trafficking of large conductance Ca2+- and voltage-activated K+ (BK) channels is regulated by Rab4 GTPase., PMID:31926210
Plasma membrane proteome of adhesion-competent endometrial epithelial cells and its modulation by Rab11a., PMID:31737970
Exocytosis of large-diameter lysosomes mediates interferon γ-induced relocation of MHC class II molecules toward the surface of astrocytes., PMID:31667557
Ras-related proteins (Rab) are key proteins related to male fertility following a unique activation mechanism., PMID:31606348
L-type prostaglandin D synthase regulates the trafficking of the PGD2 DP1 receptor by interacting with the GTPase Rab4., PMID:31575663
Cytoskeleton Protein Filamin A Is Required for Efficient Somatostatin Receptor Type 2 Internalization and Recycling through Rab5 and Rab4 Sorting Endosomes in Tumor Somatotroph Cells., PMID:31574507
For research use only. Not for human or drug use.
