Catalog No.
YHK78401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly655-Ile835
Predicted molecular weight
22.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UI47
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CTNNA3, Alpha T-catenin, Cadherin-associated protein, Catenin alpha-3
Fortilin binds CTNNA3 and protects it against phosphorylation, ubiquitination, and proteasomal degradation to guard cells against apoptosis., PMID:39747445
Genome-wide association studies of milk composition traits in indicine Badri cattle using ddRAD sequencing approach., PMID:39715884
Genome-wide scan of Flortaucipir PET levels finds JARID2 associated with cerebral tau deposition., PMID:39417126
Layer-specific proteomic profiling of human normal heart., PMID:39003999
Potential role of CTNNA3 and FRMPD4 in vascular tumorous thrombosis of colon adenocarcinoma., PMID:38727409
Genome-Wide Analysis of Milk Production Traits and Selection Signatures in Serbian Holstein-Friesian Cattle., PMID:38473054
[Detection of molecular affecting sensitivity to local glucocorticoid therapy in oral lichen planus through transcriptome sequencing]., PMID:38318893
Proteomics and phosphoproteomics of failing human left ventricle identifies dilated cardiomyopathy-associated phosphorylation of CTNNA3., PMID:37126683
Germline genetic variants and pediatric rhabdomyosarcoma outcomes: a report from the Children's Oncology Group., PMID:36951526
Rare FGFR Oncogenic Alterations in Sequenced Pediatric Solid and Brain Tumors Suggest FGFR Is a Relevant Molecular Target in Childhood Cancer., PMID:36446043
Alpha-T-catenin is expressed in peripheral nerves as a constituent of Schwann cell adherens junctions., PMID:36420826
The genetics of occupational asthma development among workers exposed to diisocyanates: A systematic literature review with meta-analysis., PMID:36276967
Decreased Expression of Plakophilin-2 and αT-Catenin in Arrhythmogenic Right Ventricular Cardiomyopathy: Potential Markers for Diagnosis., PMID:35628349
SPATA33 affects the formation of cell adhesion complex by interacting with CTNNA3 in TM4 cells., PMID:35536443
Identification of crucial circRNAs in skeletal muscle during chicken embryonic development., PMID:35484498
Oncogenic Fusions in Gliomas: An Institutional Experience., PMID:35347013
Network Theoretical Approach to Explore Factors Affecting Signal Propagation and Stability in Dementia's Protein-Protein Interaction Network., PMID:35327643
CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study., PMID:34717601
Copy number variations in a Brazilian cohort with autism spectrum disorders highlight the contribution of cell adhesion genes., PMID:34664255
Expression of ovine CTNNA3 and CAP2 genes and their association with growth traits., PMID:34481004
Identification of novel genetic susceptibility loci for thoracic and abdominal aortic aneurysms via genome-wide association study using the UK Biobank Cohort., PMID:34469433
Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation., PMID:34363682
Cell type-specific YAP1-WWTR1/TAZ transcriptional responses after autophagy perturbations are determined by levels of α-catenins (CTNNA1 and CTNNA3)., PMID:34036899
Genome-wide association study of antipsychotic-induced sinus bradycardia in Chinese schizophrenia patients., PMID:33914752
Novel Recurrent Altered Genes in Chinese Patients With Anaplastic Thyroid Cancer., PMID:33428730
A 235 Kb deletion at 17q21.33 encompassing the COL1A1, and two additional secondary copy number variants in an infant with type I osteogenesis imperfecta: A rare case report., PMID:32281310
FGFR- gene family alterations in low-grade neuroepithelial tumors., PMID:32085805
Unravelling the ultrastructural details of αT-catenin-deficient cell-cell contacts between heart muscle cells by the use of FIB-SEM., PMID:31828778
Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR Pathways., PMID:31617914
Putative role of Brugada syndrome genes in familial atrial fibrillation., PMID:31539150
Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records., PMID:30420678
Sudden unexpected death in the young - Value of massive parallel sequencing in postmortem genetic analyses., PMID:30415094
αT-catenin: A developmentally dispensable, disease-linked member of the α-catenin family., PMID:29746206
Detection of salivary protein biomarkers of saliva secretion disorder in a primary Sjögren syndrome murine model., PMID:29558726
α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart., PMID:29467248
Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy., PMID:29030101
Intercalated disc in failing hearts from patients with dilated cardiomyopathy: Its role in the depressed left ventricular function., PMID:28934278
Assessment of Three New Loci from Genome-wide Association Study in Essential Tremor in Chinese population., PMID:28801652
Co-inheritance of mutations associated with arrhythmogenic cardiomyopathy and hypertrophic cardiomyopathy., PMID:28699631
Cardiomyocytes of the Heart and Pulmonary Veins: Novel Contributors to Asthma?, PMID:28481622
Genome-wide association study in essential tremor identifies three new loci., PMID:27797806
Molecular Analysis of Hybrid Neurofibroma/Schwannoma Identifies Common Monosomy 22 and α-T-Catenin/CTNNA3 as a Novel Candidate Tumor Suppressor., PMID:27765635
αT-catenin in restricted brain cell types and its potential connection to autism., PMID:27330745
Polymorphisms of CHAT but not TFAM or VR22 are Associated with Alzheimer Disease Risk., PMID:27272392
Investigating the effects of copy number variants on reading and language performance., PMID:27186239
Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway., PMID:27091189
Are genetic tests informative in predicting food allergy?, PMID:27070332
The cardiomyocyte protein αT-catenin contributes to asthma through regulating pulmonary vein inflammation., PMID:26947180
CTNNA3 is a tumor suppressor in hepatocellular carcinomas and is inhibited by miR-425., PMID:26882563
Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome., PMID:26507551