Catalog No.
YHG20201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His16-Glu262
Predicted molecular weight
31.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q09161
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NCBP 80 kDa subunit, NCBP1, CBP80, NCBP, Nuclear cap-binding protein subunit 1, 80 kDa nuclear cap-binding protein
Proteomics analysis explored the changes in the tumor microenvironment of CT26 tumor-bearing mice after microwave ablation., PMID:40317156
Exploration of mRNA-modifying METTL3 oncogene as momentous prognostic biomarker responsible for colorectal cancer development., PMID:40177651
NCBP2 predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis., PMID:40124611
The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases., PMID:39825447
Cryo-EM structure of the CBC-ALYREF complex., PMID:39282949
Comprehensive investigation in oncogenic functions and immunological roles of NCBP2 and its validation in prostate cancer., PMID:38964031
IGF2BP3/NCBP1 complex inhibits renal tubular senescence through regulation of CDK6 mRNA stability., PMID:38945255
Helicobacter Pylori-Enhanced hnRNPA2B1 Coordinates with PABPC1 to Promote Non-m6A Translation and Gastric Cancer Progression., PMID:38887155
CMTR-1 RNA methyltransferase mutations activate widespread expression of a dopaminergic neuron-specific mitochondrial complex I gene., PMID:38810637
circular RNA circ-231 promotes protein biogenesis of TPI1 and PRDX6 through mediating the interaction of eIF4A3 with STAU1 to facilitate unwinding of secondary structure in 5' UTR, enhancing progression of human esophageal squamous cell carcinoma (ESCC)., PMID:38577609
Nonsense-mediated mRNA decay of mRNAs encoding a signal peptide occurs primarily after mRNA targeting to the endoplasmic reticulum., PMID:38513766
CD8+ T cell metabolic flexibility elicited by CD28-ARS2 axis-driven alternative splicing of PKM supports antitumor immunity., PMID:38233562
Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex., PMID:38175753
PABPN1 functions as a predictive biomarker in colorectal carcinoma., PMID:38158471
Identification and validation of N7 -methylguanosine-associated gene NCBP1 as prognostic and immune-associated biomarkers in breast cancer patients., PMID:38071502
Single-molecule quantitation of RNA-binding protein occupancy and stoichiometry defines a role for Yra1 (Aly/REF) in nuclear mRNP organization., PMID:37963019
Human IL-17A protein production is controlled through a PIP5K1α-dependent translational checkpoint., PMID:37874883
The Nuclear Cap-Binding Complex, a multitasking binding partner of RNA polymerase II transcripts., PMID:37830942
NCBP1 Improves Cognitive Function in Mice by Reducing Oxidative Stress, Neuronal Loss, and Glial Activation After Status Epilepticus., PMID:37474884
Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex., PMID:37260089
NCBP1 enhanced proliferation of DLBCL cells via METTL3-mediated m6A modification of c-Myc., PMID:37244946
Genes whose expressions in the primary lung squamous cell carcinoma are able to accurately predict the progression of metastasis through lymphatic system, inferred from a bioinformatics analyses., PMID:37185598
m7G-related genes-NCBP2 and EIF4E3 determine immune contexture in head and neck squamous cell carcinoma by regulating CCL4/CCL5 expression., PMID:37067401
Arsenic resistance protein 2 and microRNA biogenesis: Biological implications in cancer development., PMID:36933704
Temporal-iCLIP captures co-transcriptional RNA-protein interactions., PMID:36755023
The hnRNP C tetramer binds to CBC on mRNA and impedes PHAX recruitment for the classification of RNA polymerase II transcripts., PMID:36620872
An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies., PMID:36494469
A guard protein mediated quality control mechanism monitors 5'-capping of pre-mRNAs., PMID:36305816
Mechanism of electroacupuncture and herb-partitioned moxibustion on ulcerative colitis animal model: A study based on proteomics., PMID:36161055
Contemporary medicinal chemistry strategies for the discovery and optimization of influenza inhibitors targeting vRNP constituent proteins., PMID:35847499
Du13 encodes a C2 H2 zinc-finger protein that regulates Wxb pre-mRNA splicing and microRNA biogenesis in rice endosperm., PMID:35560858
Genome-wide linkage analysis combined with genome sequencing in large families with intracranial aneurysms., PMID:35228681
A putative cap binding protein and the methyl phosphate capping enzyme Bin3/MePCE function in telomerase biogenesis., PMID:35217638
Cytoplasmic switch of ARS2 isoforms promotes nonsense-mediated mRNA decay and arsenic sensitivity., PMID:35104878
Identification and Characterization of the Interaction Between the Methyl-7-Guanosine Cap Maturation Enzyme RNMT and the Cap-Binding Protein eIF4E., PMID:35026230
The C-Terminal Domains of the PB2 Subunit of the Influenza A Virus RNA Polymerase Directly Interact with Cellular GTPase Rab11a., PMID:35019720
HIV-1 hypermethylated guanosine cap licenses specialized translation unaffected by mTOR., PMID:34949712
The Cap-Binding Complex CBC and the Eukaryotic Translation Factor eIF4E: Co-Conspirators in Cap-Dependent RNA Maturation and Translation., PMID:34944805
The pioneer round of translation ensures proper targeting of ER and mitochondrial proteins., PMID:34850140
The effects of NCBP3 on METTL3-mediated m6A RNA methylation to enhance translation process in hypoxic cardiomyocytes., PMID:34382339
Identification of proteins associated with development of psoriatic arthritis in peripheral blood mononuclear cells: a quantitative iTRAQ-based proteomics study., PMID:34344401
Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF-DDX19B interaction., PMID:34232997
ARS2/SRRT: at the nexus of RNA polymerase II transcription, transcript maturation and quality control., PMID:34060620
Dual roles of the serine/arginine-rich splicing factor SR45a in promoting and interacting with nuclear cap-binding complex to modulate the salt-stress response in Arabidopsis., PMID:33421141
Cuticular waxes-A shield of barley mutant in CBP20 (Cap-Binding Protein 20) gene when struggling with drought stress., PMID:33180718
CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev., PMID:33103564
NCBP3: A Multifaceted Adaptive Regulator of Gene Expression., PMID:33032857
NCBP3 positively impacts mRNA biogenesis., PMID:32960271
Affinity proteomic dissection of the human nuclear cap-binding complex interactome., PMID:32960270
The nuclear cap-binding complex as choreographer of gene transcription and pre-mRNA processing., PMID:32873578
For research use only. Not for human or drug use.
