Catalog No.
YHK77601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr12-Glu285
Predicted molecular weight
33.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92600
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CCR4-NOT transcription complex subunit 9, CNOT9, RCD1, RQCD1, Rcd-1, Cell differentiation protein RQCD1 homolog
The Unkempt RNA binding protein reveals a local translation program in centriole overduplication., PMID:39131325
De novo variants in CNOT9 cause a neurodevelopmental disorder with or without epilepsy., PMID:37092538
The Conserved CNOT1 Interaction Motif of Tristetraprolin Regulates ARE-mRNA Decay Independently of the p38 MAPK-MK2 Kinase Pathway., PMID:35920669
N-terminal Ago-binding domain of GW182 contains a tryptophan-rich region that confer binding to the CCR4-NOT complex., PMID:35822830
Uncovering a novel function of the CCR4-NOT complex in phytochrome A-mediated light signalling in plants., PMID:33783355
αα-Hub domains and intrinsically disordered proteins: A decisive combo., PMID:33361159
Deciphering tissue-based proteome signatures revealed novel subtyping and prognostic markers for thymic epithelial tumors., PMID:31967407
The central region of CNOT1 and CNOT9 stimulates deadenylation by the Ccr4-Not nuclease module., PMID:30309886
Overexpression of miR-361-5p in triple-negative breast cancer (TNBC) inhibits migration and invasion by targeting RQCD1 and inhibiting the EGFR/PI3K/Akt pathway., PMID:29924958
Tryptophan-Mediated Interactions between Tristetraprolin and the CNOT9 Subunit Are Required for CCR4-NOT Deadenylase Complex Recruitment., PMID:29291391
Whole exome sequencing identifies a recurrent RQCD1 P131L mutation in cutaneous melanoma., PMID:25544760
A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing., PMID:24768540
Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression., PMID:24768538
Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans., PMID:24352423
Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis., PMID:20878056
Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells., PMID:19724902
Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1., PMID:18180299
Atomic model of human Rcd-1 reveals an armadillo-like-repeat protein with in vitro nucleic acid binding properties., PMID:17189474
Molecular cloning and characterization of an Rcd1-like protein in excretory-secretory products of Trichinella pseudospiralis., PMID:16899141
Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex., PMID:14707134
Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation., PMID:12356739
For research use only. Not for human or drug use.
