Catalog No.
YHF17901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser13-Arg192
Predicted molecular weight
22.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P56559
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADP-ribosylation factor-like protein LAK, ARL7, ADP-ribosylation factor-like protein 4C, ADP-ribosylation factor-like protein 7, ARL4C
The potential of ARL4C and its-mediated genes in atherosclerosis and agent development., PMID:40176913
Small GTPase ARL4C Associated with Various Cancers Affects Microtubule Nucleation., PMID:39767779
Identification of biomarkers and potential drug targets in osteoarthritis based on bioinformatics analysis and mendelian randomization., PMID:39268462
Single-Cell Multi-Dimensional data analysis reveals the role of ARL4C in driving rheumatoid arthritis progression and Macrophage polarization dynamics., PMID:39182267
Wnt/β-catenin-YAP axis in the pathogenesis of primary intraosseous carcinoma NOS, deriving from odontogenic keratocyst., PMID:38908335
Prognostic stratification of sepsis through DNA damage response based RiskScore system: insights from single-cell RNA-sequencing and transcriptomic profiling., PMID:38404591
The translational potential of miR-26 in atherosclerosis and development of agents for its target genes ACC1/2, COL1A1, CPT1A, FBP1, DGAT2, and SMAD7., PMID:38195542
The role of ARL4C in predicting prognosis and immunotherapy drug susceptibility in pan-cancer analysis., PMID:38178862
Ursolic acid inhibits the metastasis of colon cancer by downregulating ARL4C expression., PMID:38131251
Effect of Hyperbaric Oxygen and Inflammation on Human Gingival Mesenchymal Stem/Progenitor Cells., PMID:37887323
ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer., PMID:37237373
Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation., PMID:37141698
The role of Wnt, ARL4C, and Sema3A in developmental process and disease pathogenesis., PMID:37098842
Construction and validation of chemoresistance-associated tumor- infiltrating exhausted-like CD8+ T cell signature in breast cancer: cr-TILCD8TSig., PMID:36949939
ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy via notch-RBP-Jκ-H3K4Me3-OSBPL5., PMID:36366750
Cross-Tissue Analysis Using Machine Learning to Identify Novel Biomarkers for Knee Osteoarthritis., PMID:35785145
ARL4C Regulates the Progression of Clear Cell Renal Cell Carcinoma by Affecting the Wnt/β-Catenin Signaling Pathway., PMID:35774359
Identification of Neural Progenitor Cell-associated Chemoradiotherapy Resistance Gene Set (ARL4C, MSN, TNFAIP6) for Prognosis of Glioma., PMID:35718975
Clear cell squamous cell carcinoma of the tongue exhibits characteristics as an undifferentiated squamous cell carcinoma., PMID:35552085
Molecular Patterns Based on Immunogenomic Signatures Stratify the Prognosis of Colon Cancer., PMID:35237578
Identifying a novel IRF3/circUHRF1/miR-1306-5p/ARL4C axis in pancreatic ductal adenocarcinoma progression., PMID:34983293
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer., PMID:34635154
RAF1-MEK/ERK pathway-dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation., PMID:34622442
Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion., PMID:34590580
MicroRNA-302s Might Regulate ARL4C-Mediated Gastric Cancer Progression via p53 Signaling: Bioinformatics Analysis and Experiments Validation., PMID:33880033
ARL4C might serve as a prognostic factor and a novel therapeutic target for gastric cancer: bioinformatics analyses and biological experiments., PMID:33724652
The Role of ARL4C in Erlotinib Resistance: Activation of the Jak2/Stat 5/β-Catenin Signaling Pathway., PMID:33194732
A risk stratification model based on four novel biomarkers predicts prognosis for patients with renal cell carcinoma., PMID:33092599
CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis., PMID:32873638
Macrophage Lxrα reduces atherosclerosis in Ldlr-/- mice independent of Arl7 transactivation., PMID:32736671
ATF3 Demethylation Promotes the Transcription of ARL4C, Which Acts as a Tumor Suppressor in Human Breast Cancer., PMID:32425548
Clinical relevance of ARF/ARL family genes and oncogenic function of ARL4C in endometrial cancer., PMID:32070877
Decreasing Arl4c expression by inhibition of AKT signal in human lung adenocarcinoma cells., PMID:32057901
ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target., PMID:31925985
Analysis of the characteristics of chemotherapy-resistant renal cell carcinomas based on global transcriptional analysis of their tissues and cell lines., PMID:31774870
Chemically Modified Antisense Oligonucleotide Against ARL4C Inhibits Primary and Metastatic Liver Tumor Growth., PMID:30647122
Perinatal polychlorinated biphenyls and polychlorinated dibenzofurans exposure are associated with DNA methylation changes lasting to early adulthood: Findings from Yucheng second generation., PMID:30640082
ADP-ribosylation factor-like 4C predicts worse prognosis in endometriosis-associated ovarian cancers., PMID:30594917
ASO Author Reflections: ARL4C and Peritoneal Dissemination in Gastric Cancer., PMID:30556117
ARL4C stabilized by AKT/mTOR pathway promotes the invasion of PTEN-deficient primary human glioblastoma., PMID:30357833
Interferon tau-dependent and independent effects of the bovine conceptus on the endometrial transcriptome†., PMID:30203055
The formation of giant plasma membrane vesicles enable new insights into the regulation of cholesterol efflux., PMID:29522754
Knockdown of ARL4C inhibits osteogenic differentiation of human adipose-derived stem cells through disruption of the Wnt signaling pathway., PMID:29432742
Identification of ARL4C as a Peritoneal Dissemination-Associated Gene and Its Clinical Significance in Gastric Cancer., PMID:29270876
ADP-ribosylation factor-like 4C binding to filamin-A modulates filopodium formation and cell migration., PMID:28855378
Arl4c is a key regulator of tubulogenesis and tumourigenesis as a target gene of Wnt-β-catenin and growth factor-Ras signalling., PMID:28053143
Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma., PMID:27835592
Induction of expression of aryl hydrocarbon receptor-dependent genes in human HepaRG cell line modified by shRNA and treated with β-naphthoflavone., PMID:27796684
Clinical and prognostic significance of Arl4c expression in colorectal cancer., PMID:26756615
Clinically Relevant Molecular Subtypes in Leiomyosarcoma., PMID:25896974
For research use only. Not for human or drug use.
