Catalog No.
YHC78701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp65-Ser184
Predicted molecular weight
15.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P10109
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adrenodoxin, mitochondrial, Adrenal ferredoxin, Hepatoredoxin, FDX1, Ferredoxin-1, ADX
Electron Paramagnetic Resonance Insights into Direct Electron Transfer Between FDX1 and Elesclomol-Cu2+ complex in Cuproptosis., PMID:40484707
A molecular basis of Ferredoxin Reductase (FdxR) mutations that result in mitochondriopathies., PMID:40479788
Mycobacterium tuberculosis stimulates cuproptosis by regulating Lnc-Gm5532 to target FDX1 for bacteria intracellular survival., PMID:40449270
NUDT21 lactylation reprograms alternative polyadenylation to promote cuproptosis resistance., PMID:40425546
Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations., PMID:40360795
Copper's new role in cancer: how cuproptosis-related genes could revolutionize glioma treatment., PMID:40355831
[Effect and mechanism of Shenmai Injection in regulating copper death in myocardial fibrosis in rats]., PMID:40350947
Interplay of Ferroptosis, Cuproptosis, Autophagy and Pyroptosis in Male Infertility: Molecular Crossroads and Therapeutic Opportunities., PMID:40331931
Combining ATAC-seq and RNA-seq reveals key genes for gonadal abnormalities in one-month-old XX-DSD pigs., PMID:40329180
α-Synuclein targeted therapy with multiple pathological improvement for Parkinson's disease by macrocyclic amphiphile nanomedicine., PMID:40319681
Cu(OH)2 nanopesticide induced liver dysfunction in mice by targeting lipoylated tricarboxylic acid cycle proteins via ferredoxin 1., PMID:40311425
Hypoxia-induced autophagy attenuates ferredoxin 1-mediated cuproptosis in colorectal cancer cells., PMID:40294285
FDX1 Regulates the Phosphorylation of ATM, DNA-PKcs Akt, and EGFR and Affects Radioresistance Under Severe Hypoxia in the Glioblastoma Cell Line T98G., PMID:40244269
Copper-Doped Polydopamine Nanoparticles-Mediated GSH/GPX4-Depleted Ferroptosis and Cuproptosis Sensitizes Lung Tumor to Checkpoint Blockade Immunotherapy., PMID:40231637
A pillar[5]arene-based hyaluronic acid-decorated amorphous bimetallic metal-organic framework for multimodal synergistic cancer therapy., PMID:40210065
The Role of Cuproptosis in Hyperoxia-Induced Lung Injury and Its Potential for Treatment., PMID:40195958
Chlorophyllin exerts synergistic anti-tumor effect with gemcitabine in pancreatic cancer by inducing cuproptosis., PMID:40186145
Copper oxide nanoparticles induce pulmonary inflammation via triggering cellular cuproptosis., PMID:40180017
Induction of Cuproptosis by Dichloromethane Extract From Patrinia scabiosaefolia Fisch on K562 Cells., PMID:40177825
o8G-modified circKIAA1797 promotes lung cancer development by inhibiting cuproptosis., PMID:40176113
[Quercetin ameliorates myocardial injury in diabetic rats by regulating L-type calcium channels]., PMID:40159968
FDX1 overexpression inhibits the growth and metastasis of clear cell renal cell carcinoma by upregulating FMR1 expression., PMID:40118855
Activation of PI3K-AKT pathway prevents steroid-induced osteonecrosis of the femoral head via inhibiting Cuproptosis., PMID:40089548
Effect of spermidine on cuproptosis in follicular granulosa cells., PMID:40072410
The proteomic landscape of trophoblasts unravels calcium-dependent syncytialization processes and beta-chorionic gonadotropin (ß-hCG) production., PMID:40038668
Edaravone dextranol alleviates ferroptosis, Cuproptosis, and blood-brain barrier damage after acute cerebral infarction., PMID:40029474
Atomically dispersed copper(I) on tungstosilicic acid for catalytic protection against cisplatin-induced hearing loss., PMID:39991827
Fibroblast growth factor receptor 3 mutation promotes HSPB6-mediated cuproptosis in hypochondroplasia by impairing chondrocyte autophagy., PMID:39991457
Knocking Down Ferredoxin 1 Inhibits the Progression of Colorectal Cancer and Regulates Cuproptosis via Mediating the Hippo Signaling Pathway., PMID:39987563
CYFIP1 coordinate with RNMT to induce osteosarcoma cuproptosis via AURKAIP1 m7G modification., PMID:39984834
AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple-Negative Breast Cancer., PMID:39976173
The Potential Mechanism of Cuproptosis in Hemocytes of the Pacific Oyster Crassostrea gigas upon Elesclomol Treatment., PMID:39936990
Targeting FDX1 by trilobatin to inhibit cuproptosis in doxorubicin-induced cardiotoxicity., PMID:39933533
SRF/SLC31A1 signaling promotes cuproptosis induced by celastrol in NSCLC., PMID:39930648
Peripheral mitochondrial transplantation alleviates diabetes-associated cognitive dysfunction by suppressing cuproptosis., PMID:39924054
TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis., PMID:39920765
MT2A promotes angiogenesis in chronically ischemic brains through a copper-mitochondria regulatory mechanism., PMID:39915841
Metallothionein rescues doxorubicin cardiomyopathy via mitigation of cuproptosis., PMID:39793852
The study on cuproptosis in Alzheimer's disease based on the cuproptosis key gene FDX1., PMID:39759399
Ferredoxin 2 Is Critical for Tumor Suppression and Lipid Homeostasis but Dispensable for Embryonic Development., PMID:39732391
Assembly of a biomimetic copper-based nanocomplex for alleviating hypoxia to enhance cuproptosis against osteosarcoma and lung metastasis., PMID:39710219
Anti-FDX1 Autoantibody as a Potential Biomarker for Non-Small Cell Lung Cancer Detection., PMID:39699293
Knocking Down LncRNA-GAS5 Restores the Inhibition of Cuprotosis Protein FDX-1 by Acinetobacter baumannii., PMID:39670641
Lenvatinib-activated NDUFA4L2/IL33/PADI4 pathway induces neutrophil extracellular traps that inhibit cuproptosis in hepatocellular carcinoma., PMID:39585643
Elabela alleviates cuproptosis and vascular calcification in vitaminD3- overloaded mice via regulation of the PPAR-γ /FDX1 signaling., PMID:39567863
[The role of peritumoral electroacupuncture in regulating cuproptosis for sensitization of chemotherapy efficacy in mice with triple-negative breast cancer]., PMID:39557431
Engineered bacterial lipoate protein ligase A (lplA) restores lipoylation in cell models of lipoylation deficiency., PMID:39547509
Rhomboid-like 2 correlated with TME infiltration inhibits cuproptosis-related genes and drives malignant phenotype in clear cell renal cell carcinoma., PMID:39511359
Developmental and Molecular Effects of C-Type Natriuretic Peptide Supplementation in In Vitro Culture of Bovine Embryos., PMID:39456721
Copper-coordinated nanomedicine for the concurrent treatment of lung cancer through the induction of cuproptosis and apoptosis., PMID:39437977
For research use only. Not for human or drug use.
