Catalog No.
YHA79801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp126-Pro346
Predicted molecular weight
28.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43827
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Angiopoietin-related protein 7, Angiopoietin-like protein 7, Cornea-derived transcript 6 protein, ANGPTL7, Angiopoietin-like factor, CDT6
Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork., PMID:39847376
Predicting gene signature in breast cancer patients with multiple machine learning models., PMID:39352418
Ferroptosis-related genes DUOX1 and HSD17B11 affect tumor microenvironment and predict overall survival of lung adenocarcinoma patients., PMID:39259123
Olink Profiling of Aqueous Humor Identifies Novel Biomarkers for Wet Age-Related Macular Degeneration., PMID:38902972
ANGPTL7 and Its Role in IOP and Glaucoma., PMID:38497513
Genes as drugs for glaucoma: latest advances., PMID:38117663
Cord blood stem cell‑derived Angptl7 ameliorates the severity of bronchopulmonary dysplasia via anti‑inflammatory and proangiogenic effects., PMID:37997800
Integrated Analysis of Transcriptome and Proteome of the Human Cornea and Aqueous Humor Reveal Novel Biomarkers for Corneal Endothelial Cell Dysfunction., PMID:37895034
Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases., PMID:37550624
Screening of key genes related to ferroptosis and a molecular interaction network analysis in colorectal cancer using machine learning and bioinformatics., PMID:37435214
Identification of potential prognostic markers for lung adenocarcinoma using comprehensive analysis., PMID:37350390
The non-cell-autonomous function of ID1 promotes AML progression via ANGPTL7 from the microenvironment., PMID:37319434
Rare protective variants and glaucoma-relevant cell stressors modulate Angiopoietin-like 7 expression., PMID:37220876
Metastasis from the tumor interior and necrotic core formation are regulated by breast cancer-derived angiopoietin-like 7., PMID:36853945
Expression and Regulation of a Novel Decidual Cells-Derived Estrogen Target during Decidualization., PMID:36613747
Development and validation of a novel model for predicting the survival of bladder cancer based on ferroptosis-related genes., PMID:36399105
Brain molecular mechanisms in Rasmussen encephalitis., PMID:36336987
ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma., PMID:36192519
A Single-Cell Survey of Cellular Heterogeneity in Human Great Saphenous Veins., PMID:36078120
Increased plasma ANGPTL7 levels with increased obstructive sleep apnea severity., PMID:36017324
ANGPTL7 is transcriptionally regulated by SP1 and modulates glucocorticoid-induced cross-linked actin networks in trabecular meshwork cells via the RhoA/ROCK pathway., PMID:35136015
Distinct Clinical Impact and Biological Function of Angiopoietin and Angiopoietin-like Proteins in Human Breast Cancer., PMID:34685578
Gene expression signature as a surrogate marker of microvascular invasion on routine hepatocellular carcinoma biopsies., PMID:34624411
Effects of mechanical stress and deficiency of dihydrotestosterone or 17β-estradiol on Temporomandibular Joint Osteoarthritis in mice., PMID:34500105
MicroRNA Profiles of Maternal and Neonatal Endothelial Progenitor Cells in Preeclampsia., PMID:34070163
Single-cell RNA sequencing redefines the mesenchymal cell landscape of mouse endometrium., PMID:33710643
Antiglaucoma Potential of β-Glucogallin Is Mediated by Modulating Mitochondrial Responses in Experimentally Induced Glaucoma., PMID:33571990
Cord Blood Levels of Angiopoietin-Like 7 (ANGPTL7) in Preterm Infants., PMID:33313310
Single-cell RNA-seq identifies unique transcriptional landscapes of human nucleus pulposus and annulus fibrosus cells., PMID:32943704
Angptl7 promotes insulin resistance and type 2 diabetes mellitus by multiple mechanisms including SOCS3-mediated IRS1 degradation., PMID:32786125
Angiopoietin-like protein 7 mediates TNF-α-induced adhesion and oxidative stress in human umbilical vein epithelial cell., PMID:32525822
Mining the role of angiopoietin-like protein family in gastric cancer and seeking potential therapeutic targets by integrative bioinformatics analysis., PMID:32410376
Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma., PMID:32369491
Angiopoietin-Like Protein 7 and Short-Term Mortality in Acute Heart Failure., PMID:31962333
Lycium Barbarum Exerts Protection against Glaucoma-Like Injury Via Inhibition of MMP-9 Signaling In Vitro., PMID:31860907
Effect of ANGPTL7 on Proliferation and Differentiation of MC3T3-E1 Cells., PMID:31835268
Stem Cells from Human Trabecular Meshwork Hold the Potential to Develop into Ocular and Non-Ocular Lineages After Long-Term Storage., PMID:31680626
Stem cell-driven lymphatic remodeling coordinates tissue regeneration., PMID:31672914
Angiopoietin-Like 7 Contributes to Angiotensin II-Induced Proliferation, Inflammation and Apoptosis in Vascular Smooth Muscle Cells., PMID:31302653
Genetic programming of macrophages generates an in vitro model for the human erythroid island niche., PMID:30787325
Identification of differentially expressed genes and their upstream regulators in colorectal cancer., PMID:28409560
Plasma and adipose tissue level of angiopoietin-like 7 (ANGPTL7) are increased in obesity and reduced after physical exercise., PMID:28264047
Evolution of the angiopoietin-like gene family in teleosts and their role in skin regeneration., PMID:28086749
Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq., PMID:27855634
PAX6 regulates human corneal epithelium cell identity., PMID:27818314
Protein-coding genes combined with long non-coding RNAs predict prognosis in esophageal squamous cell carcinoma patients as a novel clinical multi-dimensional signature., PMID:27714034
[To Protect Corneal Transparency against Diseases]., PMID:27164760
Angiopoietin-Like Protein 7 Promotes an Inflammatory Phenotype in RAW264.7 Macrophages Through the P38 MAPK Signaling Pathway., PMID:26973239
Cd11b(+) myeloid cells support hepatic metastasis through down-regulation of angiopoietin-like 7 in cancer cells., PMID:25854806
Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells., PMID:25652910