Catalog No.
YHF05801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly15-Ile239
Predicted molecular weight
27.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P54819
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AK2, ADK2, Adenylate kinase 2, mitochondrial, Adenylate monophosphate kinase, ATP-AMP transphosphorylase 2, AK 2, ATP:AMP phosphotransferase
A fluorescent sensor for real-time monitoring of DPP8/9 reveals crucial roles in immunity and cancer., PMID:40355159
DPP8/9 processing of human AK2 unmasks an IAP binding motif., PMID:40312560
Quantitative tissue analysis reveals AK2, COL1A1, and PLG protein signatures: targeted therapeutics for meningioma: Erratum., PMID:40085767
Andrographolide ameliorates sepsis-induced acute liver injury by attenuating endoplasmic reticulum stress through the FKBP1A-mediated NOTCH1/AK2 pathway., PMID:40053226
Ancestral retrovirus envelope protein ERVWE1 upregulates circ_0001810, a potential biomarker for schizophrenia, and induces neuronal mitochondrial dysfunction via activating AK2., PMID:39543767
Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis., PMID:39378586
Quantitative tissue analysis reveals AK2, COL1A1, and PLG protein signatures: targeted therapeutics for meningioma., PMID:39288025
Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer's disease treatment., PMID:38701714
Immunolabeling for filaggrin and acidic keratins in the granular layer of mammalian epidermis indicates that an acidic-basic interaction is involved in cornification., PMID:38677234
NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome., PMID:38598835
A novel metabolism-related gene signature in patients with hepatocellular carcinoma., PMID:38025761
Identification of biomarkers associated with pediatric asthma using machine learning algorithms: A review., PMID:38013370
UK-5099, a mitochondrial pyruvate carrier inhibitor, recovers impaired neutrophil maturation caused by AK2 deficiency in human pluripotent stem cell models., PMID:37949028
Lysyl oxidase-like 3 restrains mitochondrial ferroptosis to promote liver cancer chemoresistance by stabilizing dihydroorotate dehydrogenase., PMID:37253718
The amino-dipeptidyl peptidases DPP8 and DPP9: Purification and enzymatic assays., PMID:37230592
Metagenomic analysis and antibacterial activity of kefir microorganisms., PMID:37222548
The palmitoyltransferase ZDHHC21 regulates oxidative phosphorylation to induce differentiation block and stemness in AML., PMID:37216691
The association of ODF4 with AK1 and AK2 in mice is essential for fertility through its contribution to flagellar shape., PMID:36804949
A circular network of purine metabolism as coregulators of dilated cardiomyopathy., PMID:36401332
Non-Histone Lysine Crotonylation Is Involved in the Regulation of White Fat Browning., PMID:36361522
Whole-exome sequencing in 415,422 individuals identifies rare variants associated with mitochondrial DNA copy number., PMID:36311265
Combined Hybridization and Evaluation of High-Lysine Rice: Nutritional and Physicochemical Qualities and Field Performance., PMID:36293019
Biosynthesis of Silver Chloride Nanoparticles (AgCl-NPs) from Extreme Halophiles and Evaluation of Their Biological Applications., PMID:35881211
Influence of Brevibacillus borestelensis strains on phytoremediation potential and biomolecules contents of Jatropha curcas on diluted chromium sludge soil., PMID:35738403
AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis., PMID:35585049
Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody., PMID:34930213
AK2 Promotes the Migration and Invasion of Lung Adenocarcinoma by Activating TGF-β/Smad Pathway In vitro and In vivo., PMID:34630090
Mutational patterns and their correlation to CHIP-related mutations and age in hematological malignancies., PMID:34570179
An Integrated Bioinformatics Analysis of the Potential Regulatory Effects of miR-21 on T-cell Related Target Genes in Multiple Sclerosis., PMID:34484645
Multiple Sclerosis: circRNA Profile Defined Reveals Links to B-Cell Function., PMID:34385287
Identification, characterization, and cloning of a novel aminoacylase, L-pipecolic acid acylase from Pseudomonas species., PMID:34176819
Reclamation competence of Crotalaria juncea with the amalgamation and influence of indigenous bacteria on a waste dump of bauxite mine., PMID:34134423
Genome-wide association study and inbreeding depression on body size traits in Qira black sheep (Ovis aries)., PMID:34096079
Rab5b-Associated Arf1 GTPase Regulates Export of N-Myristoylated Adenylate Kinase 2 From the Endoplasmic Reticulum in Plasmodium falciparum., PMID:33604307
Adenylate kinase AK2 isoform integral in embryo and adult heart homeostasis., PMID:33571905
Circ-AK2 is associated with preeclampsia and regulates biological behaviors of trophoblast cells through miR-454-3p/THBS2., PMID:33129036
Lysine biofortification in rice by modulating feedback inhibition of aspartate kinase and dihydrodipicolinate synthase., PMID:32945115
Proteasomal degradation induced by DPP9-mediated processing competes with mitochondrial protein import., PMID:32815200
Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency., PMID:32796067
TREC and KREC profiling as a representative of thymus and bone marrow output in patients with various inborn errors of immunity., PMID:32691468
Reticular dysgenesis caused by an intronic pathogenic variant in AK2., PMID:32532877
Role of arginine kinase in Paramecium tetraurelia (Ciliophora, Peniculida): Subcellular localization of AK3 and phosphoarginine shuttle system in cilia., PMID:32464434
Retrospective cohort study of trifluridine/tipiracil (TAS-102) plus bevacizumab versus trifluridine/tipiracil monotherapy for metastatic colorectal cancer., PMID:31881856
Hypomorphic variants in AK2 reveal the contribution of mitochondrial function to B-cell activation., PMID:31862378
A model for reticular dysgenesis shows impaired sensory organ development and hair cell regeneration linked to cellular stress., PMID:31727854
Reticular Dysgenesis and Mitochondriopathy Induced by Adenylate Kinase 2 Deficiency with Atypical Presentation., PMID:31673062
Quantitative proteomic analysis reveals AK2 as potential biomarker for late normal tissue radiotoxicity., PMID:31399108
Genome-Wide Analysis of DNA Methylation and Antituberculosis Drug-Induced Liver Injury in the Han Chinese Population., PMID:31247120
Regulators of cell movement during development and regeneration in Drosophila., PMID:31039676
Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer's disease., PMID:31019427
For research use only. Not for human or drug use.
