Catalog No.
YHG50102
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu41-Asp366
Predicted molecular weight
38.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13363
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CTBP, C-terminal-binding protein 1, CTBP1, CtBP1
C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation., PMID:40490364
Transcriptome-Wide Analysis and Experimental Validation from FFPE Tissue Identifies Stage-Specific Gene Expression Profiles Differentiating Adenoma, Carcinoma In-Situ and Adenocarcinoma in Colorectal Cancer Progression., PMID:40362431
Profiling of Circulating Cell-free DNA Methylation Patterns Identifies Aberrant Methylated CTBP1 Promotor Sites for Prediction of Alzheimer's Disease., PMID:40302267
Unveiling the multifaceted roles of long non-coding RNA CTBP1-DT in human diseases: Special attention to its microprotein-encoding potential., PMID:40020329
CXXC5 function blockade promotes diabetic wound healing through stimulating fibroblast and vascular endothelial cell activation., PMID:40001144
Evaluating the healing effects of docosahexaenoic acid in neonates with bilirubin-induced brain injury., PMID:39988369
The specificity of CTBP dehydrogenase inhibitors MTOB and 4-Cl-HIPP., PMID:39967797
Endothelial monocarboxylate transporter 1 drives atherosclerosis via a lactate/NADH/CtBP-mediated transrepression pathway., PMID:39949978
Proteomic analysis of the nonstructural protein 2-host protein interactome reveals a novel regulatory role of SH3 domain-containing kinase-binding protein 1 in porcine reproductive and respiratory syndrome virus replication and apoptosis., PMID:39755310
Clinical significance and biological roles of lncRNA CTBP1-AS in polycystic ovary syndrome., PMID:39702404
CtBP1 is essential for epigenetic silencing of μ-opioid receptor genes in the dorsal root ganglion in spinal nerve ligation-induced neuropathic pain., PMID:39580324
TOP2A Promotes Proliferation, Migration, and Inflammatory Response in M5-Treated Keratinocytes by Binding CTBP1 to Activate Wnt/β-Catenin Signaling., PMID:39565516
Loss of paired immunoglobin-like type 2 receptor B gene associated with age-related macular degeneration impairs photoreceptor function in mouse retina., PMID:39532089
Clinical significance of peripheral blood DDR1 and CtBP gene methylation detection in patients with acute pancreatitis., PMID:39485950
CTBP1 links metabolic syndrome to polycystic ovary syndrome through interruption of aromatase and SREBP1., PMID:39294274
Ling-gui-zhu-gan promotes adipocytes browning via targeting the miR-27b/PRDM16 pathway in 3T3-L1 cells., PMID:39206264
ZNF623 contributes to breast carcinoma progress by recruiting CtBP1 to regulate NF-κB pathway., PMID:38959528
C-Terminal Binding Protein: Regulator between Viral Infection and Tumorigenesis., PMID:38932279
Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2., PMID:38748792
Identification and characterization of a new potent inhibitor targeting CtBP1/BARS in melanoma cells., PMID:38711119
Large-scale cross-ancestry genome-wide meta-analysis of serum urate., PMID:38658550
Endothelial nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome regulation in atherosclerosis., PMID:38626254
CCL2 regulated by the CTBP1-AS2/miR-335-5p axis promotes hemangioma progression and angiogenesis., PMID:38622049
Identify CTBP1-DT as an immunological biomarker that promotes lipid synthesis and apoptosis resistance in KIRC., PMID:38521112
Phytochemical Screening, In Silico Molecular Docking, ADME Properties, and In Vitro Antioxidant, Anticancer, and Antidiabetic Activity of Marine Halophyte Suaeda maritima (L.) Dumort., PMID:38496978
LncRNA CTBP1-AS inhibits TP63-mediated activation of S100A14 during prostate cancer progression., PMID:38476086
Transcriptional corepressor activity of CtBP1 is regulated by ISG15 modification., PMID:38405356
Er:YAG Laser Alleviates Inflammaging in Diabetes-Associated Periodontitis via Activation CTBP1-AS2/miR-155/SIRT1 Axis., PMID:38396793
A novel CTBP1 variant in a Chinese pediatric patient with a phenotype distinct from hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome., PMID:38348454
Dysregulated lncRNAs regulate human umbilical cord mesenchymal stem cell differentiation into insulin-producing cells by forming a regulatory network with mRNAs., PMID:38273351
LINC MIR503HG Controls SC-β Cell Differentiation and Insulin Production by Targeting CDH1 and HES1., PMID:38243869
Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway., PMID:38183983
Suppression of DNMT2/3 by proinflammatory cytokines inhibits CtBP1/2-dependent genes to promote the occurrence of atrophic nonunion., PMID:37979214
Expression Analyses of C-Terminal-Binding Protein 1 (CtBP1) during Mouse Brain Development., PMID:37906993
The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression., PMID:37809459
Glycolysis Promotes Angiotensin II-Induced Aortic Remodeling Through Regulating Endothelial-to-Mesenchymal Transition via the Corepressor C-Terminal Binding Protein 1., PMID:37795602
CRISPR/Cas9-Mediated CtBP1 Gene Editing Enhances Chemosensitivity and Inhibits Metastatic Potential in Esophageal Squamous Cell Carcinoma Cells., PMID:37762332
Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer., PMID:37707363
Accumulation of advanced glycation end products promotes atrophic nonunion incidence in mice through a CtBP1/2-dependent mechanism., PMID:37696386
H19 in Serum Extracellular Vesicles Reflects Resistance to AR Axis-targeted Therapy Among CRPC Patients., PMID:37643783
The DDUP protein encoded by the DNA damage-induced CTBP1-DT lncRNA confers cisplatin resistance in ovarian cancer., PMID:37633920
Identification of small-molecule inhibitors against the interaction of RNA-binding protein PSF and its target RNA for cancer treatment., PMID:37388923
JAC4 Inhibits EGFR-Driven Lung Adenocarcinoma Growth and Metastasis through CTBP1-Mediated JWA/AMPK/NEDD4L/EGFR Axis., PMID:37240137
MAT1A Suppression by the CTBP1/HDAC1/HDAC2 Transcriptional Complex Induces Immune Escape and Reduces Ferroptosis in Hepatocellular Carcinoma., PMID:37230466
Toosendanin Restrains Idiopathic Pulmonary Fibrosis by Inhibiting ZEB1/CTBP1 Interaction., PMID:37138491
CtBP Neuroprotective Role in Toxin-Based Parkinson's Disease Models: From Expression Pattern to Dopaminergic Survival., PMID:37060501
A pathogenic CTBP1 variant featuring HADDTS with dystrophic myopathology., PMID:37037050
Proteomic Analysis of Skeletal Muscle and White Adipose Tissue after Aerobic Exercise Training in High Fat Diet Induced Obese Mice., PMID:36982812
Succinylation of CTBP1 mediated by KAT2A suppresses its inhibitory activity on the transcription of CDH1 to promote the progression of prostate cancer., PMID:36764210
The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration., PMID:36688959
For research use only. Not for human or drug use.
