Catalog No.
YHK76301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser207-Glu325
Predicted molecular weight
15.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96CX2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Predominantly fetal expressed T1 domain, KIAA1778, Pfetin, KCTD12, BTB/POZ domain-containing protein KCTD12, PFET1, C13orf2
Proteomic signatures of retinal pigment epithelium-derived exosomes in myopic and non-myopic tree shrew eyes., PMID:40330779
Male-specific lethal 1 (MSL1) promotes Erastin-induced ferroptosis in colon cancer cells by regulating the KCTD12-SLC7A11 axis., PMID:40221412
RNA-binding protein expression based machine learning model predicts metastasis and treatment outcome of testicular cancer., PMID:40138122
Integration of osimertinib-targeted EGFR gene-associated differential gene expression in constructing a prognostic model for lung adenocarcinoma., PMID:39661202
Smooth operator(s): dialing up and down neurotransmitter responses by G-protein regulators., PMID:39054106
Profiling the proximal proteome of the activated μ-opioid receptor., PMID:38528119
KCTD5 Forms Hetero-Oligomeric Complexes with Various Members of the KCTD Protein Family., PMID:37762619
A pan-cancer analysis of potassium channel tetramerization domain containing 12 in human cancer., PMID:37626178
IL-6-Mediated Upregulated miRNAs in Extracellular Vesicles Derived from Lund Human Mesencephalic (LUHMES) Cells: Effects on Astrocytes and Microglia., PMID:37238588
Protein Networks Associated with Native Metabotropic Glutamate 1 Receptors (mGlu1) in the Mouse Cerebellum., PMID:37174725
The Oncosuppressive Properties of KCTD1: Its Role in Cell Growth and Mobility., PMID:36979172
Integrative analyses of radiation-related genes and biomarkers associated with breast cancer., PMID:36647876
A nomogram for predicting prognosis of multiple myeloma patients based on a ubiquitin-proteasome gene signature., PMID:36534449
Comprehensive analysis of KCTD family genes associated with hypoxic microenvironment and immune infiltration in lung adenocarcinoma., PMID:35705627
LINC00365 inhibited lung adenocarcinoma progression and glycolysis via sponging miR-429/KCTD12 axis., PMID:35426242
KCTD12 is a prognostic marker of breast cancer and correlates with tumor immune cell infiltration., PMID:35116258
KCTD8 and KCTD12 Facilitate Axonal Expression of GABAB Receptors in Habenula Cholinergic Neurons., PMID:35017224
Preliminary study of genome-wide association identified novel susceptibility genes for thyroid-related hormones in Chinese population., PMID:34533693
Astrocyte-derived extracellular vesicles enhance the survival and electrophysiological function of human cortical neurons in vitro., PMID:33631652
The effects of Kctd12, an auxiliary subunit of GABAB receptor in dentate gyrus on behavioral response to chronic social defeat stress in mice., PMID:33285230
Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics., PMID:32961112
Reduction of SCUBE3 by a new marine-derived asterosaponin leads to arrest of glioma cells in G1/S., PMID:32764572
Proteomics Profiling of KAIMRC1 in Comparison to MDA-MB231 and MCF-7., PMID:32570693
KCTD12 promotes G1/S transition of breast cancer cell through activating the AKT/FOXO1 signaling., PMID:32207860
Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation., PMID:32003940
Downregulation of KCTD12 contributes to melanoma stemness by modulating CD271., PMID:31565480
Lithium and GADL1 regulate glycogen synthase kinase-3 activity to modulate KCTD12 expression., PMID:31311980
KCTD: A new gene family involved in neurodevelopmental and neuropsychiatric disorders., PMID:31197948
Genome-wide association analysis reveals KCTD12 and miR-383-binding genes in the background of rumination., PMID:30886212
Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction., PMID:30872078
Structural basis for KCTD-mediated rapid desensitization of GABAB signalling., PMID:30814734
Contribution of KCTD12 to esophageal squamous cell carcinoma., PMID:30157793
KCTD12 is negatively regulated by Kit in gastrointestinal stromal tumors., PMID:29930747
Insights into the Proteome of Gastrointestinal Stromal Tumors-Derived Exosomes Reveals New Potential Diagnostic Biomarkers., PMID:29242380
GABAB receptor subtypes differentially regulate thalamic spindle oscillations., PMID:29106983
KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition., PMID:28869606
KCTD12 modulation of GABA(B) receptor function., PMID:28713569
Evolutionary history of Tibetans inferred from whole-genome sequencing., PMID:28448578
Targeted Proteomics for Multiplexed Verification of Markers of Colorectal Tumorigenesis., PMID:28062797
KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABAB Receptor-Induced K+ Currents., PMID:28003345
Lentiviral-mediated overexpression of KCTD12 inhibits the proliferation of human uveal melanoma OCM-1 cells., PMID:28000887
Behavioural endophenotypes in mice lacking the auxiliary GABAB receptor subunit KCTD16., PMID:27717812
KCTD12 Auxiliary Proteins Modulate Kinetics of GABAB Receptor-Mediated Inhibition in Cholecystokinin-Containing Interneurons., PMID:27073217
KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway., PMID:26847701
Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins., PMID:25974686
Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABAB receptors associated with mood disorders., PMID:25689571
Mechanisms of fast desensitization of GABA(B) receptor-gated currents., PMID:25637440
Kctd12 and Ulk2 partner to regulate dendritogenesis and behavior in the habenular nuclei., PMID:25329151
GABAB receptor phosphorylation regulates KCTD12-induced K⁺ current desensitization., PMID:25065880
Pfetin as a risk factor of recurrence in gastrointestinal stromal tumors., PMID:24977158
For research use only. Not for human or drug use.
