Catalog No.
YHA25601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser1127-Thr1285
Predicted molecular weight
20.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14646
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-dependent helicase CHD1, CHD1, Chromodomain-helicase-DNA-binding protein 1, CHD-1
Regulation of DNA translocation of chromatin remodeler enzyme Chd1 by exit DNA unwrapping., PMID:40453884
The WAC-downWAC domain in the yeast ISW2 nucleosome remodeling complex forms a structural module essential for ISW2 function but not cell viability., PMID:40399979
CHD1 loss reprograms SREBP2-driven cholesterol synthesis to fuel androgen-responsive growth and castration resistance in SPOP-mutated prostate tumors., PMID:40360905
Structural basis of human CHD1 nucleosome recruitment and pausing., PMID:40334658
Full-length Chd1 of Coprinopsis cinerea is expressed after the dark period required for fruiting body maturation and impacts meiotic progression., PMID:40306610
CHD1 dysregulation in cancer: bridging chromatin instability, therapy resistance, and immune evasion., PMID:40278910
Environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin induces non-obstructive azoospermia: New insights from network toxicology, integrated machine learning, and biomolecular modeling., PMID:40215689
BINDER achieves accurate identification of hierarchical TADs by comprehensively characterizing consensus TAD boundaries., PMID:40097199
Semisynthesis of Isomerized Histone H4 Reveals Robustness and Vulnerability of Chromatin toward Molecular Aging., PMID:39894946
A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes., PMID:39677735
Discovery of CHD1 Antagonists for PTEN-Deficient Prostate Cancer., PMID:39508435
Identification and functional characteristics of CHD1L gene variants implicated in human Müllerian duct anomalies., PMID:39342328
Finish the unfinished: Chd1 resolving hexasome-nucleosome complex with FACT., PMID:39303676
Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression., PMID:39294262
Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT., PMID:39270644
How does CHD4 slide nucleosomes?, PMID:39221830
Prognosis and metabolism with a Golgi apparatus-related genes-based formula in breast cancer., PMID:39151519
Human Genetics of Ventricular Septal Defect., PMID:38884729
SOSTDC1 Nuclear Translocation Facilitates BTIC Maintenance and CHD1-Mediated HR Repair to Promote Tumor Progression and Olaparib Resistance in TNBC., PMID:38864559
Genome wide nucleosome landscape shapes 3D chromatin organization., PMID:38848364
Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C., PMID:38809771
Comprehensive Analysis of the Expression, Prognosis, and Immune Infiltrates for Chromodomain-Helicase-DNA-Binding Proteins in Breast Tumor., PMID:38809626
Increased frequency of CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression without inducing homologous recombination deficiency., PMID:38645014
A genome-wide comprehensive analysis of nucleosome positioning in yeast., PMID:38266035
A Saudi Girl With Co-occurring CHD1 (Pilarowski-Bjornsson Syndrome) and ASH1L Gene Variants., PMID:38174187
Chromatin gatekeeper and modifier CHD proteins in development, and in autism and other neurological disorders., PMID:37851134
Bi-directional nucleosome sliding by the Chd1 chromatin remodeler integrates intrinsic sequence-dependent and ATP-dependent nucleosome positioning., PMID:37738162
Acute Kidney Injury (AKI) in COVID-19: In silico Identification of LncRNA-MiRNA-Gene Networks and Key Transcription Factors., PMID:37584353
ESS2 controls prostate cancer progression through recruitment of chromodomain helicase DNA binding protein 1., PMID:37524814
Coregulators Reside within Drosophila Ecdysone-Inducible Loci before and after Ecdysone Treatment., PMID:37511602
Nucleosome retention by histone chaperones and remodelers occludes pervasive DNA-protein binding., PMID:37493599
Somatic and Germline Variants Affect Prognosis and Susceptibility in Prostate Cancer., PMID:37351993
Discovery of novel serum biomarkers for diagnosing and predicting postmenopausal osteoporosis patients by 4D-label free protein omics., PMID:37203779
Whole-genome sequencing identifies novel predictors for hematopoietic cell transplant outcomes for patients with myelodysplastic syndrome: a CIBMTR study., PMID:37041565
Transcriptional regulation of autophagy by chromatin remodeling complex and histone variant., PMID:37039545
Intertwined Dysregulation of Ribosomal Proteins and Immune Response Delineates SARS-CoV-2 Vaccination Breakthroughs., PMID:37022180
Establishment and function of chromatin organization at replication origins., PMID:37020028
High-Performance PCR for Alleles Discrimination of Chromo-Helicase-DNA Binding Protein (CHD1) Gene in Bird Sexing., PMID:36829577
CHD1, a multifaceted epigenetic remodeler in prostate cancer., PMID:36776288
Gene therapy targeting miR‑212‑3p exerts therapeutic effects on MAFLD similar to those of exercise., PMID:36633140
CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer., PMID:36629160
Identification of novel Mendelian disorders of the epigenetic machinery (MDEMs)-associated functional mutations and neurodevelopmental disorders., PMID:36625521
LncRNA LINC02535 Induces Colorectal Adenocarcinoma Progression via Modulating miR-30d-5p/CHD1., PMID:36577835
Frontotemporal degeneration genetic risk loci and transcription regulation as a possible mechanistic link to disease risk., PMID:36253972
To bind or not to bind: Cistromic reprogramming in prostate cancer., PMID:36212399
MiR-30a-5p/CHD1 axis enhances cisplatin sensitivity of ovarian cancer cells via inactivating the Wnt/β-catenin pathway., PMID:36206129
Role of mitochondrial translation in remodeling of energy metabolism in ER/PR(+) breast cancer., PMID:36119536
Regulation of sensory perception and motor abilities by brain-specific action of chromatin remodeling factor CHD1., PMID:35983070
Suppressor mutations that make the essential transcription factor Spn1/Iws1 dispensable in Saccharomyces cerevisiae., PMID:35977387
Role of ATP-dependent chromatin remodelers in hematopoietic stem and progenitor cell maintenance., PMID:35787545
For research use only. Not for human or drug use.
