Catalog No.
YHK76201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg121
Predicted molecular weight
16.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q5TA89
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BHLHB38, Transcription factor HES-5, Class B basic helix-loop-helix protein 38, bHLHb38, Hairy and enhancer of split 5, HES5
NINJ1 exerts a role in the development of preeclampsia through potential regulation by the Notch1 signaling pathway., PMID:40289260
Hes5+ astrocytes potentiate primary afferent Aδ and C fiber-mediated excitatory synaptic transmission to spinal lamina I neurons., PMID:40289116
Buyang Huanwu decoction improves motor function by enhancing internal capsule reorganization through inhibiting Notch signaling after ischemic stroke., PMID:40245964
The combinatorial binding syntax of transcription factors in forebrain-specific enhancers., PMID:39976127
Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis., PMID:39835478
Limited Adipogenic Differentiation Potential of Human Dental Pulp Stem Cells Compared to Human Bone Marrow Stem Cells., PMID:39456888
Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control., PMID:39358374
Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors., PMID:39133301
[The Role of Notch Signaling Pathway in Adult Patients with Epstein-Barr Virus-induced Infectious Mononucleosis]., PMID:38926989
Cerebellar granular neuron progenitors exit their germinative niche via BarH-like1 activity mediated partly by inhibition of T-cell factor., PMID:38860486
System biology approach to identify the novel biomarkers in glioblastoma multiforme tumors by using computational analysis., PMID:38841373
Notch1 regulates hepatic thrombopoietin production., PMID:38603632
ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis through H3K4me3 Modification., PMID:38582368
Laminar-selective spinal astrocyte population capable of converting tactile information into nociceptive in rats., PMID:38485349
Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model., PMID:38417575
Transplantation of Wnt3a-modified neural stem cells promotes neural regeneration and functional recovery after spinal cord injury via Wnt-Gli2 pathway., PMID:37983663
[High homocysteine level promotes autophagy and apoptosis of mouse hippocampal HT22 cells through the Notch1/Hes1 signaling pathway]., PMID:37933657
Epigenetically dysregulated NOTCH-Delta-HES signaling cascade can serve as a subtype classifier for acute lymphoblastic leukemia., PMID:37922005
Conditional Deletion of Foxg1 Delayed Myelination during Early Postnatal Brain Development., PMID:37762220
Notch Signaling Plays a Dual Role in Regulating the Neuron-to-Oligodendrocyte Switch in the Developing Dorsal Forebrain., PMID:37640551
Notch3/Hes5 Induces Vascular Dysfunction in Hypoxia-Induced Pulmonary Hypertension Through ER Stress and Redox-Sensitive Pathways., PMID:37254738
Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5., PMID:36764520
A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain., PMID:36550333
Fluoxetine shows neuroprotective effects against LPS-induced neuroinflammation via the Notch signaling pathway., PMID:36461606
SOX8 Knockdown Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer by Inhibiting the Notch Signaling Pathway., PMID:36246971
Human Parvovirus B19 Nonstructural Protein 1 Regulates GATA1 Expression via the Notch Signaling Pathway in K562 Cell Line., PMID:36224006
Inferring and perturbing cell fate regulomes in human brain organoids., PMID:36198796
Dynamic switching of lateral inhibition spatial patterns., PMID:36000231
Effects of hyperbaric oxygen on Notch signaling pathway after severe carbon monoxide poisoning in mice., PMID:35946219
Magnesium Ions Promote In Vitro Rat Bone Marrow Stromal Cell Angiogenesis Through Notch Signaling., PMID:35870071
GRWD1 affects the proliferation, apoptosis, invasion and migration of triple negative breast cancer through the Notch signaling pathway., PMID:35761807
Pancreatic-Like Cells Derived From Mouse Embryonic Stem Cells Are Regulated by Pdx1 Involving the Notch Pathway., PMID:35695761
γ-secretase inhibitor disturbs the morphological development of differentiating neurons through affecting Notch/miR-342-5p., PMID:35364125
A "notch" in the cellular communication network in response to anoxia by wood frog (Rana sylvatica)., PMID:35283291
Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation., PMID:35246225
Zuogui pills maintain the stemness of oogonial stem cells and alleviate cyclophosphamide-induced ovarian aging through Notch signaling pathway., PMID:35217439
Upregulated NOTCH Signaling in the Lens of Patients With Pseudoexfoliation Syndrome Compared With Pseudoexfoliation Glaucoma Suggests Protective Role., PMID:35210385
RYBP modulates embryonic neurogenesis involving the Notch signaling pathway in a PRC1-independent pattern., PMID:34798064
Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module., PMID:34772946
YTHDF2 Suppresses Notch Signaling through Post-transcriptional Regulation on Notch1., PMID:34671198
Electroacupuncture in promoting neural repair after spinal cord injury: Inhibiting the Notch signaling pathway and regulating downstream proteins expression., PMID:34636492
African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling., PMID:34517008
Maternal high-fat diet increases anhedonic behavior and modulates hippocampal Mash1 and BDNF expression in adult offspring., PMID:34509569
Using the lineage determinants Olig2 and Sox10 to explore transcriptional regulation of oligodendrocyte development., PMID:34480425
Immune cells and Notch1 signaling appear to drive the epithelial to mesenchymal transition in the development of adenomyosis in mice., PMID:34463756
Vortioxetine mitigates neuronal damage by restricting PERK/eIF2α/ATF4/CHOP signaling pathway in rats subjected to focal cerebral ischemia-reperfusion., PMID:34358549
Genome-wide DNA methylation and gene expression analyses in monozygotic twins identify potential biomarkers of depression., PMID:34341332
Evolution of hes gene family in vertebrates: the hes5 cluster genes have specifically increased in frogs., PMID:34325655
Revealing NOTCH-dependencies in synaptic targets associated with Alzheimer's disease., PMID:34314836
Identification of novel candidate genes implicated in odontogenic potential in the developing mouse tooth germ using transcriptome analysis., PMID:34302633
For research use only. Not for human or drug use.
