Catalog No.
YHK76001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp314-Leu476
Predicted molecular weight
21.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96QF0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Rabin-3, Rab3A-interacting protein, Rab-3A-interacting protein, SSX2-interacting protein, RAB3IP, RABIN8
Rabin8 phosphorylated by NDR2, the canine early retinal degeneration gene product, directs rhodopsin Golgi-to-cilia trafficking., PMID:39774853
Experimental and proteomics evidence revealed the protective mechanisms of Shemazhichuan Liquid in attenuating neutrophilic asthma., PMID:39515107
Mechanisms underlying morphological and functional changes of cilia in fibroblasts derived from patients bearing ARL3T31A and ARL3T31A/C118F mutations., PMID:38457249
MicroRNA‑126 protects SH‑SY5Y cells from ischemia/reperfusion injury‑induced apoptosis by inhibiting RAB3IP., PMID:34935056
LINC00943 knockdown attenuates MPP+-induced neuronal damage via miR-15b-5p/RAB3IP axis in SK-N-SH cells., PMID:33208053
Long noncoding RNA NEAT1 knockdown inhibits MPP+-induced apoptosis, inflammation and cytotoxicity in SK-N-SH cells by regulating miR-212-5p/RAB3IP axis., PMID:32442477
Whole-transcriptome analysis reveals a potential hsa_circ_0001955/hsa_circ_0000977-mediated miRNA-mRNA regulatory sub-network in colorectal cancer., PMID:32221048
Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing., PMID:31831727
The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis., PMID:31467083
Guanine nucleotide exchange factors activate Rab8a for Toll-like receptor signalling., PMID:30843452
LncRNA HOTAIR targets miR-126-5p to promote the progression of Parkinson's disease through RAB3IP., PMID:30738012
Promotion of Cell Proliferation through Inhibition of Cell Autophagy Signalling Pathway by Rab3IP is Restrained by MicroRNA-532-3p in Gastric Cancer., PMID:30519341
An interaction network between the SNARE VAMP7 and Rab GTPases within a ciliary membrane-targeting complex., PMID:30404838
Rab3IP interacts with SSX2 and enhances the invasiveness of gastric cancer cells., PMID:30005870
Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1)., PMID:29073233
Proteomics insights into infantile neuronal ceroid lipofuscinosis (CLN1) point to the involvement of cilia pathology in the disease., PMID:28334871
Rab3 interacting molecule 3 mutations associated with autism alter regulation of voltage-dependent Ca²⁺ channels., PMID:26142343
The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting., PMID:25673879
Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance., PMID:24976218
GRAB is a binding partner for the Rab11a and Rab11b GTPases., PMID:24140058
Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis., PMID:23704319
Novel genes that mediate nuclear respiratory factor 1-regualted neurite outgrowth in neuroblastoma IMR-32 cells., PMID:23219993
Purification and functional properties of a Rab8-specific GEF (Rabin3) in action remodeling and polarized transport., PMID:16473595
The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP., PMID:12007189
RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channels., PMID:11988172
The death domain of Rab3 guanine nucleotide exchange protein in GDP/GTP exchange activity in living cells., PMID:11853534
A post-docking role for active zone protein Rim., PMID:11559854
GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase., PMID:11516400
Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A., PMID:7532276
For research use only. Not for human or drug use.
