Catalog No.
YHK75901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys177-Gly420
Predicted molecular weight
31.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q7Z5R6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Proline-rich protein 73, RIAM, RARP-1, APBB1-interacting protein 1, Rap1-GTP-interacting adapter molecule, PREL-1, Proline-rich EVH1 ligand 1, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, PREL1, RARP1, APBB1IP, Retinoic acid-responsive proline-rich protein 1
Multi-modal immune dynamics of pre-COVID-19 Kawasaki Disease following intravenous immunoglobulin., PMID:39186994
MET receptor serves as a promising target in melanoma brain metastases., PMID:38386085
Identification of renal ischemia reperfusion injury-characteristic genes, pathways and immunological micro-environment features through bioinformatics approaches., PMID:38329418
Epigenome-wide methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2+): a prospective cohort study in the United States., PMID:37932662
Quantitative phosphoproteomics reveals molecular pathway network alterations in human early-stage primary hepatic carcinomas: potential for 3P medical approach., PMID:37605650
Bioinformatics analysis of the key genes in osteosarcoma metastasis and immune invasion., PMID:36345453
Expression of the phagocytic receptors αMβ2 and αXβ2 is controlled by RIAM, VASP and Vinculin in neutrophil-differentiated HL-60 cells., PMID:36238292
Transcription factor regulation of eQTL activity across individuals and tissues., PMID:35100260
Expression of immune-related genes as prognostic biomarkers for the assessment of osteosarcoma clinical outcomes., PMID:34916564
Structural, biochemical, and functional properties of the Rap1-Interacting Adaptor Molecule (RIAM)., PMID:34601137
Talin rod domain-containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation., PMID:34264272
Immunological Role and Prognostic Value of APBB1IP in Pan-Cancer Analysis., PMID:33391455
Phosphorylation of RIAM by src promotes integrin activation by unmasking the PH domain of RIAM., PMID:33275877
Distinct integrin activation pathways for effector and regulatory T cell trafficking and function., PMID:33104169
Talin dissociates from RIAM and associates to vinculin sequentially in response to the actomyosin force., PMID:32561773
Circ-APBB1IP as a Prognostic Biomarker Promotes Clear Cell Renal Cell Carcinoma Progression Through The ERK1/2 Signaling Pathway., PMID:32547313
Phagocytic Integrins: Activation and Signaling., PMID:32425937
RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment., PMID:32397169
Rap1 and membrane lipids cooperatively recruit talin to trigger integrin activation., PMID:31578239
A targeted proteomics approach reveals a serum protein signature as diagnostic biomarker for resectable gastric cancer., PMID:31151932
Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation., PMID:30733287
Comparative analysis of histologically classified oligodendrogliomas reveals characteristic molecular differences between subgroups., PMID:29631562
The adaptor molecule RIAM integrates signaling events critical for integrin-mediated control of immune function and cancer progression., PMID:28831022
A putative molecular network associated with colon cancer metastasis constructed from microarray data., PMID:28629469
The Rap1-RIAM-talin axis of integrin activation and blood cell function., PMID:27207789
Structural comparison of yeast and human intra-mitochondrial lipid transport systems., PMID:27068958
A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration., PMID:26419705
Effects of PRELI in Oxidative-Stressed HepG2 Cells., PMID:26275693
Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes., PMID:26071602
Method development for quantification of five tear proteins using selected reaction monitoring (SRM) mass spectrometry., PMID:24408985
Two modes of integrin activation form a binary molecular switch in adhesion maturation., PMID:23468527
RIAM (Rap1-interacting adaptor molecule) regulates complement-dependent phagocytosis., PMID:23420480
Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector., PMID:23045549
Focal adhesion disassembly is regulated by a RIAM to MEK-1 pathway., PMID:22946047
Binding properties and stability of the Ras-association domain of Rap1-GTP interacting adapter molecule (RIAM)., PMID:22523535
A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network., PMID:22228203
CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules., PMID:22117043
Rap1-GTP-interacting adaptor molecule (RIAM) protein controls invasion and growth of melanoma cells., PMID:21454517
Rap1 controls activation of the α(M)β(2) integrin in a talin-dependent manner., PMID:20665668
[RIAM: bridge between Rap1 and integrin]., PMID:20622482
RIAM regulates the cytoskeletal distribution and activation of PLC-gamma1 in T cells., PMID:19952372
RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences., PMID:19098287
Integrin activation., PMID:18363565
PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins., PMID:16783873
Rap1 regulation of RIAM and cell adhesion., PMID:16757337
[Inside-out integrin activation links micro- to macro-dynamics]., PMID:16719319
A novel family of mitochondrial proteins is represented by the Drosophila genes slmo, preli-like and real-time., PMID:15700158
PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins., PMID:15642358
RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion., PMID:15469846
For research use only. Not for human or drug use.
