Catalog No.
YHC86301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser226-Val480
Predicted molecular weight
30.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11172
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
OMPdecase, OPRT, OPRTase, UMP synthase, ODC, Uridine 5'-monophosphate synthase, UMPS
Identifying prognostic targets in metastatic prostate cancer beyond AR., PMID:40405591
In vitro VS in vivo transcriptional approach provides new insight on temporal cold response which works without root system in tea plant (Camellia sinensis (L.) Kuntze)., PMID:40393231
De novo NAD+ synthesis is ineffective for NAD+ supply in axenically cultured Caenorhabditis elegans., PMID:40175694
Identification of target genes co-regulated by four key histone modifications of five key regions in hepatocellular carcinoma., PMID:39349287
Resistance to 5-fluorouracil: The molecular mechanisms of development in colon cancer cells., PMID:39241942
Bioinformatics analysis and experimental verification of the cancer-promoting effect of DHODH in clear cell renal cell carcinoma., PMID:38796629
p53 activation enhances the sensitivity of non-small cell lung cancer to the combination of SH003 and docetaxel by inhibiting de novo pyrimidine synthesis., PMID:38704578
Does maropitant provide more effective perioperative pain management than meloxicam in bitches undergoing ovariohysterectomy? The first report on the comparison of visceral algesia-analgesia for ovariohysterectomy., PMID:38335894
GPX3-Mediated Oxidative Stress Affects Pyrimidine Metabolism Levels in Stomach Adenocarcinoma via the AMPK/mTOR Pathway., PMID:38322113
Structural and functional properties of uridine 5'-monophosphate synthase from Coffea arabica., PMID:38184030
Instrument shank-assisted ovariohysterectomy: a randomized clinical trial of surgical and pain alleviation efficiency of a single-person modified technique., PMID:37915948
De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence., PMID:37291265
N-carbamoyl aspartate reduced body weight by stimulating the thermogenesis of iBAT., PMID:37163935
Frequent EGFR exon 20 insertion in the so-called peripheral-type squamous cell neoplasm of uncertain malignant potential: a variant of bronchiolar adenoma or under-recognised entity?, PMID:36864007
Differential haplotype expression in class I MHC genes during SARS-CoV-2 infection of human lung cell lines., PMID:36818472
Human uridine 5'-monophosphate synthase stores metabolic potential in inactive biomolecular condensates., PMID:36708921
Unconventional microbial proteases as promising tools for the production of bioactive protein hydrolysates., PMID:36377687
Genome-wide CRISPR Screening Reveals Pyrimidine Metabolic Reprogramming in 5-FU Chronochemotherapy of Colorectal Cancer., PMID:35903686
Prognostic Utility of the Ki-67 Labeling Index in Follicular Thyroid Tumors: a 20-Year Experience from a Tertiary Thyroid Center., PMID:35305239
A multiauxotrophic CHO cell line for the rapid isolation of producers of diverse or high levels of recombinant proteins., PMID:35249214
UBE2T-mediated Akt ubiquitination and Akt/β-catenin activation promotes hepatocellular carcinoma development by increasing pyrimidine metabolism., PMID:35169125
A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict clinically relevant toxicity associated with fluoropyrimidine and platinum-based chemotherapy in gastric cancer., PMID:34525956
Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?, PMID:34011619
Carboxylesterase 1 polymorphisms are associated with clinical outcomes in gastroenteric cancer patients treated with capecitabine., PMID:33586000
Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells., PMID:33201894
Spatial Distribution Patterns of Clinically Relevant TERT Promoter Mutations in Follicular Thyroid Tumors of Uncertain Malignant Potential: Advantages of the Digital Droplet PCR Technique., PMID:33197629
UPEFinder: A Bioinformatic Tool for the Study of Uncharacterized Proteins Based on Gene Expression Correlation and the PageRank Algorithm., PMID:33155801
Identification of a Twelve-Gene Signature and Establishment of a Prognostic Nomogram Predicting Overall Survival for Medulloblastoma., PMID:33101383
Downregulation of miR-125b-5p and Its Prospective Molecular Mechanism in Lung Squamous Cell Carcinoma., PMID:32614608
The transcription factors aryl hydrocarbon receptor and MYC cooperate in the regulation of cellular metabolism., PMID:32611766
LncRNA SNORD3A specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression., PMID:32382150
BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals., PMID:31311867
Clear Cell Variant of a Follicular Thyroid Tumor With Uncertain Malignant Potential: A Case Report., PMID:30370813
Launching the C-HPP neXt-CP50 Pilot Project for Functional Characterization of Identified Proteins with No Known Function., PMID:30269496
One-step generation of multiple gene knock-outs in the diatom Phaeodactylum tricornutum by DNA-free genome editing., PMID:30254261
Metabolic engineering using iterative self-cloning to improve lipid productivity in Coccomyxa., PMID:30082815
RNA sequencing reveals significant miRNAs in Atypical endometrial hyperplasia., PMID:29709726
Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC., PMID:28847964
Comparison of postoperative pain and inflammation reaction in dogs undergoing preventive laparoscopic-assisted and incisional gastropexy., PMID:28717065
Uridine monophosphate synthetase enables eukaryotic de novo NAD+ biosynthesis from quinolinic acid., PMID:28559281
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase., PMID:28388410
A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis., PMID:28347333
Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences., PMID:28205048
Combined clinical and ultrasound follow-up assists in malignancy detection in Galectin-3 negative Thy-3 thyroid nodules., PMID:26475496
Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma., PMID:27733154
ABCC2-24C > T polymorphism is associated with the response to platinum/5-Fu-based neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients., PMID:27487151
Core Proteomic Analysis of Unique Metabolic Pathways of Salmonella enterica for the Identification of Potential Drug Targets., PMID:26799565
Investigation of Potentially Deleterious Alleles for Response to Cancer Treatment with 5-Fluorouracil., PMID:26637924
Role of cd56 and e-cadherin expression in the differential diagnosis of papillary thyroid carcinoma and suspected follicular-patterned lesions of the thyroid: the prognostic importance of e-cadherin., PMID:26097548
Identification of B cells participated in the mechanism of postmenopausal women osteoporosis using microarray analysis., PMID:25785089
For research use only. Not for human or drug use.
