Catalog No.
YHG72001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser254-Pro442
Predicted molecular weight
23.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14142
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA0129, Tripartite motif-containing protein 14, TRIM14
TRIM14 restricts tembusu virus infection through degrading viral NS1 protein and activating type I interferon signaling., PMID:40435148
Identification of TRIM21 and TRIM14 as Antiviral Factors Against Langat and Zika Viruses., PMID:40431659
TRIM14-NF-κB pathway in the anterior cingulate cortex modulates comorbid depressive symptoms in chronic pain., PMID:40200729
Cannabidiol-loaded hydrogel microneedle patches inhibit TRIM14/TRAF3/ NF-κB axis for the treatment of psoriasis., PMID:39933682
Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1-infected women is associated with lower viral loads., PMID:39902043
Targeting the TRIM14/USP14 Axis Enhances Immunotherapy Efficacy by Inducing Autophagic Degradation of PD-L1., PMID:38924473
Circ_RPPH1 facilitates progression of breast cancer via miR-1296-5p/TRIM14 axis., PMID:38816350
Trim14-IκBα Signaling Regulates Chronic Inflammatory Pain in Rats and Osteoarthritis Patients., PMID:38697463
Deciphering the similarities and disparities of molecular mechanisms behind respiratory epithelium response to HCoV-229E and SARS-CoV-2 and drug repurposing, a systems biology approach., PMID:38652363
Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans., PMID:38508400
TRIM14 suppressed the progression of NSCLC via hexosamine biosynthesis pathway., PMID:38267812
m6A-Mediated Upregulation of lncRNA CHASERR Promotes the Progression of Glioma by Modulating the miR-6893-3p/TRIM14 Axis., PMID:38193984
RNF125, transcriptionally regulated by NFATC2, alleviates osteoarthritis via inhibiting the Wnt/β-catenin signaling pathway through degrading TRIM14., PMID:37951197
Mechanotransduction in response to ECM stiffening impairs cGAS immune signaling in tumor cells., PMID:37804510
JMJD2D stabilises and cooperates with HBx protein to promote HBV transcription and replication., PMID:37701334
TRIM14 Overexpression Induces Chemoresistance and Malignant Behaviors of Hepatocellular Carcinoma Cells by Activating the STAT3/HIF-1α Pathway., PMID:37628777
An Antiviral Role for TRIM14 in Ebola Virus Infection., PMID:37562033
Tripartite motif‑containing 14 may aggravate cardiac hypertrophy via the AKT signalling pathway in neonatal rat cardiomyocytes and transgenic mice., PMID:37503784
Identification of key modules and driving genes in nonalcoholic fatty liver disease by weighted gene co-expression network analysis., PMID:37488473
Expression Profiling of the Tripartite Motif Family Genes in Chronic Hepatitis C Patients., PMID:37483213
Transcriptomic profiles of the ruminal wall in Italian Mediterranean dairy buffaloes fed green forage., PMID:36941576
Circular RNA circ_0000741/miR-379-5p/TRIM14 signaling axis promotes HDAC inhibitor (SAHA) tolerance in glioblastoma., PMID:36905560
CircIRAK1 aggravates ox-LDL-induced endothelial cell injury in atherosclerosis via TRIM14 upregulation by binding to miR-330-5p., PMID:36336926
Exosomal circ_0091741 promotes gastric cancer cell autophagy and chemoresistance via the miR-330-3p/TRIM14/Dvl2/Wnt/β-catenin axis., PMID:36323918
Piperlongumine-inhibited TRIM14 signaling sensitizes glioblastoma cells to temozolomide treatment., PMID:36202175
Extracellular Vesicle-Mediated miR-150-3p Delivery in Joint Homeostasis: A Potential Treatment for Osteoarthritis?, PMID:36078172
Circ_ROBO2/miR-186-5p/TRIM14 axis regulates oxidized low-density lipoprotein-induced cardiac microvascular endothelial cell injury., PMID:35620639
The TRIM14-USP14-BRCC3 complex epigenetically regulates inflammation through inhibiting OPTN-mediated autophagic degradation of KDM4D., PMID:35311471
TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation., PMID:35145029
Circular RNA circ_0048764 promotes the development of breast cancer by regulating microRNA-1296-5p/tripartite motif containing 14 axis., PMID:34787066
Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway., PMID:34656078
miR-671-5p repressed progression of papillary thyroid carcinoma via TRIM14., PMID:34292652
LncRNA MSC-AS1 Promotes Colorectal Cancer Progression by Regulating miR-325/TRIM14 Axis., PMID:34054957
miR-4443 targets TRIM14 to suppress metastasis and energy metabolism of papillary thyroid carcinoma (PTC) in vitro., PMID:34051007
Identification of targets of JS-K against HBV-positive human hepatocellular carcinoma HepG2.2.15 cells with iTRAQ proteomics., PMID:34001947
TRIM14 regulates melanoma malignancy via PTEN/PI3K/AKT and STAT3 pathways., PMID:33982666
Trim14 promotes osteoclastogenesis and noncanonical NF-κB activation by targeting p100/p52 in chronic periodontitis., PMID:33901321
Circ_0004104 knockdown alleviates oxidized low-density lipoprotein-induced dysfunction in vascular endothelial cells through targeting miR-328-3p/TRIM14 axis in atherosclerosis., PMID:33892646
Human TRIM14 protects transgenic mice from influenza A viral infection without activation of other innate immunity pathways., PMID:33864033
Long non-coding RNA OIP5-AS1 contributes to cisplatin resistance of oral squamous cell carcinoma through the miR-27b-3p/TRIM14 axis., PMID:33692839
Inhibition of TRIM14 protects cerebral ischemia/reperfusion injury through regulating NF-κB/NLRP3 pathway-mediated inflammation and apoptosis., PMID:33691569
Zenglv Fumai Granule protects cardiomyocytes against hypoxia/reoxygenation-induced apoptosis via inhibiting TRIM28 expression., PMID:33398366
Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis., PMID:33316781
Tripartite motif‑containing 14 regulates cell proliferation and apoptosis in cervical cancer via the Akt signaling pathway., PMID:33174608
Characterization of the Gene Expression Patterns in the Murine Liver Following Intramuscular Administration of Baculovirus., PMID:33115550
Expression profile of Tripartite motif family (TRIM) in human fibroblasts (NHDF) infected with porcine endogenous retrovirus (PERV)., PMID:33037648
Investigating genetic drivers of dermatomyositis pathogenesis using meta-analysis., PMID:33015383
TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection., PMID:32404352
Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10., PMID:32220948
Disturbed Yin-Yang balance: stress increases the susceptibility to primary and recurrent infections of herpes simplex virus type 1., PMID:32140387
For research use only. Not for human or drug use.
