Catalog No.
YHF24901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser58-Gly141
Predicted molecular weight
23.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P58012
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FOXL2, Forkhead box protein L2
H3K9me3 Involved in FOXL2 Regulation of SerpinE2 Expression to Affect Steroid Hormone Synthesis in Follicular Granulosa Cells., PMID:40512073
Genome-Wide Identification and Expression Analysis of Zona Pellucida (ZP) Gene Family in Cynoglossus semilaevis., PMID:40508155
Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby., PMID:40481762
A novel variant in the MAP3K1 genomic locus reveals abnormal cell apoptosis as a potential pathogenic mechanism in 46, XY disorders of sex development., PMID:40476564
Spatiotemporal and single-cell atlases to dissect regional specific cell types of the developing ovary., PMID:40461746
An Inducible CYP19A1 Excision Model for Sexual Differentiation in Chicken (Gallus gallus) via the CRISPR/Cas9 System., PMID:40284798
Functional analysis of a novel FOXL2 mutation in blepharophimosis, ptosis, and epicanthus inversus syndrome type II and elucidation of the genotype-phenotype correlation., PMID:40251640
An inducible FOXL2-dependent mouse model of ovarian adult type granulosa cell tumor., PMID:40221170
Regulation of FOXL2 gene in ovarian granulosa cell tumor by JNK inhibitor., PMID:40204754
Effects of Huluan decotion on cyclophosphamide-induced autoimmune premature ovarian failure in murine models., PMID:40151113
FOXL2 drives the differentiation of supporting gonadal cells in early ovarian development., PMID:40102860
Epigenetic Perspectives and Their Prognostic Value in Early Recurrence After Hepatocellular Carcinoma Resection., PMID:40075616
Unveiling the role of FOXL2 in female differentiation and disease: a comprehensive review†., PMID:39976382
Dose-dependent role of AMH and AMHR2 signaling in male differentiation and regulation of sex determination in Spotted knifejaw (Oplegnathus punctatus) with X1X1X2X2/X1X2Y chromosome system., PMID:39893368
Molecular Characterization and Expression of unc-13d in the Sex Reversal of Monopterus albus., PMID:39858121
A Dynamic Shift in Estrogen Receptor Expression During Granulosa Cell Differentiation in the Ovary., PMID:39834231
Protective effect of luteinizing hormone on frozen-thawed ovarian follicles and granulosa cells., PMID:39808671
Sex determination factor, a novel male-linked gene in the sea cucumber Apostichopus japonicus: Molecular characterization, expression patterns and effects of gene knockdown., PMID:39778676
CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds., PMID:39776254
FOXL2 Knockdown Inhibits the Progression of Endometriosis., PMID:39776079
A novel CUL4B gene variant activating Wnt4/β-catenin signal pathway to karyotype 46, XY female with disorders of sex development., PMID:39773765
Complex immunohistochemical and molecular study on 5 cases of ovarian juvenile granulosa cell tumors reveals a consistent alteration in the PI3K/AKT/mTOR signaling pathway., PMID:39773640
Ovarian Adult Granulosa Cell Tumors: A Scoping Review of DNA Alterations and Their Known Significance., PMID:39740818
Foxo1 directs the transdifferentiation of mouse Sertoli cells into granulosa-like cells., PMID:39681193
Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2C134W Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors., PMID:39652611
[Small cell carcinoma of the ovary of hypercalcaemic type: a clinicopathological analysis of sixteen cases]., PMID:39648003
The Molecular Landscape of 227 Adult Granulosa Cell Tumors of the Ovary: Insights into the Progression from Primary to Recurrence., PMID:39615884
Early ovarian differentiation in the tammar wallaby and the effects of exposure to bisphenol A., PMID:39569971
Transcriptomic analysis of melatonin on the mechanism of embryonic gonadal development in female Jilin white geese., PMID:39566171
Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles., PMID:39545410
Ovarian Sex Cord-Stromal Neoplasms: An Overview of Molecular Events and How to Correlate Morphology With Molecular Findings., PMID:39492459
A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV., PMID:39484396
Long Noncoding RNAs Expressed in Mouse Pituitary Development and Mature Hormone-Producing Cells., PMID:39487735
Computational insights into irinotecan's interaction with UBE2I in ovarian and endometrial cancers., PMID:39476484
Identification, expression, and function analysis of Rbpms2 splicing variants in Japanese flounder gonad., PMID:39414089
Zebrafish Foxl2l functions in proliferating germ cells for female meiotic entry., PMID:39341446
Association of FOXL2 and ERCC6 variants with premature ovarian insufficiency and their potential use in clinical IVF guidance., PMID:39277148
foxl2l is a germ cell-intrinsic gatekeeper of oogenesis in zebrafish., PMID:39257375
pSTAT3 activation of Foxl2 initiates the female pathway underlying temperature-dependent sex determination., PMID:39226347
Discovery of a proteolysis targeting chimera (PROTAC) as a potent regulator of FOXP3., PMID:39222889
Characterization and expression patterns of the Fox gene family under heat and cold stress in Manila clam Ruditapes philippinarum based on genome-wide identification., PMID:39216278
Pathological characteristics of SRY-negative 38,XX-DSD pigs: A family case report., PMID:39190944
miR-34 negatively regulates the expression of Dmrt and related genes in the testis of mud crab Scylla paramamosain., PMID:39128537
Comparable to 17α- methyl testosterone, dietary supplements of Tribulus terrestris and Mucuna pruriens promote the development of mono-sex, all-male tilapia fry, growth, survival rate and sex-related genes (Amh, Sox9, Foxl2, Dmrt1)., PMID:39026327
Insights into the role of FoxL2 in tebuconazole-induced male- biased sex differentiation of zebrafish., PMID:38977095
FOXO1 induced fatty acid oxidation in hepatic cells by targeting ALDH1L2., PMID:38923573
Role of ERβ in the ovary and ovary related diseases., PMID:38906392
Landscape of potential germline pathogenic variants in select cancer susceptibility genes in patients with adult-type ovarian granulosa cell tumors., PMID:38898688
Human Genetics of Ventricular Septal Defect., PMID:38884729
A computational analysis of the molecular mechanisms underlying the effects of ibuprofen and dibutyl phthalate on gene expression in fish., PMID:38845962
For research use only. Not for human or drug use.
