Catalog No.
YHH86601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys386-Ser568
Predicted molecular weight
22.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q53EP0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NS5ABP37, HCV NS5A-binding protein 37, FAD104, Fibronectin type III domain-containing protein 3B, Factor for adipocyte differentiation 104, FNDC3B
FNDC3B promotes gastric cancer metastasis via interacting with FAM83H and preventing its proteasomal degradation., PMID:40450207
Tumor cell-intrinsic circular RNA circFNDC3B attenuates CD8+ T cells infiltration in non-small cell lung cancer., PMID:40341878
Whole-genome sequencing identifies novel loci for keratoconus and facilitates risk stratification in a Han Chinese population., PMID:39762938
CircFNDC3B inhibits vascular smooth muscle cells proliferation in abdominal aortic aneurysms by targeting the miR-1270/PDCD10 axis., PMID:39658211
A novel protein FNDC3B-267aa encoded by circ0003692 inhibits gastric cancer metastasis via promoting proteasomal degradation of c-Myc., PMID:38802851
Regulation of Alternative Splicing of Lipid Metabolism Genes in Sepsis-Induced Liver Damage by RNA-Binding Proteins., PMID:38727856
Identification of fibronectin type III domain containing 3B as a potential prognostic and therapeutic target for pancreatic cancer: a preliminary analysis., PMID:38581008
E2F1 promotes cell migration in hepatocellular carcinoma via FNDC3B., PMID:38403291
Hypoxia increases the biogenesis of IGF2BP3-bound circular RNAs., PMID:38329630
Identification of DNA methylation biomarkers for evaluating cardiovascular disease risk from epigenome profiles altered by low-dose ionizing radiation., PMID:38303056
Identification of miRNA, lncRNA and circRNA associated with gastric cancer metabolism through sequencing and bioinformatics analysis., PMID:38290402
Circ_FNDC3B Promotes Cell Proliferation and Metastasis in Esophageal Squamous Cell Carcinoma via Regulating MAPK1 by Binding to miR-136-5p., PMID:38228844
Fibronectin Type III Domain Containing 3B as a Potential Prognostic and Therapeutic Biomarker for Glioblastoma., PMID:38137388
A RBM47 and IGF2BP1 mediated circular FNDC3B-FNDC3B mRNA imbalance is involved in the malignant processes of osteosarcoma., PMID:38129874
circFNDC3B promotes esophageal squamous cell carcinoma progression by targeting MYO5A via miR-370-3p/miR-136-5p., PMID:37667251
Clinical and genomic characterization of an ATRA-insensitive acute promyelocytic leukemia variant with a FNDC3B::RARB fusion., PMID:37283355
Lack of Association of Polymorphism Located Upstream of ABCA1 (rs2472493), in FNDC3B (rs7636836), and Near ANKRD55-MAP3K1 Genes (rs61275591) in Primary Open-Angle Glaucoma Patients of Saudi Origin., PMID:36980976
Circ-FNDC3B Functions as an Oncogenic Factor in Esophageal Squamous Cell Carcinoma via Upregulating MYO5A by Absorbing miR-136-5p and miR-370-3p., PMID:36884165
Emerging landscape of circFNDC3B and its role in human malignancies., PMID:36793611
Circ_0000285 regulates nasopharyngeal carcinoma progression through miR-1278/FNDC3B axis., PMID:36738165
Expression and prognosis analyses of the fibronectin type-III domain-containing (FNDC) protein family in human cancers: A Review., PMID:36626432
m6A-modified circFNDC3B inhibits colorectal cancer stemness and metastasis via RNF41-dependent ASB6 degradation., PMID:36446779
FNDC3B protects steatosis and ferroptosis via the AMPK pathway in alcoholic fatty liver disease., PMID:36336231
Integrated machine learning methods identify FNDC3B as a potential prognostic biomarker and correlated with immune infiltrates in glioma., PMID:36275754
Genome-wide association analysis of milk production, somatic cell score, and body conformation traits in Holstein cows., PMID:36268046
CircFNDC3B knockdown restrains the progression of oesophageal squamous cell carcinoma through miR-214-3p/CDC25A axis., PMID:36184488
Overexpression of circFNDC3B promotes the progression of oral tongue squamous cell carcinoma through the miR-1322/MED1 axis., PMID:35916453
Exosomal circRNA FNDC3B promotes the progression of esophageal squamous cell carcinoma by sponging miR-490-5p and regulating thioredoxin reductase 1 expression., PMID:35703190
Long Non-Coding RNA DUXAP8 Acts as an Oncogene in Sinonasal Squamous Cell Carcinoma Through miR-584-5p/FNDC3B Pathway., PMID:35695194
Biomarkers for primary open-angle glaucoma progression., PMID:35278478
Novel Mutations Identified in the Chinese Han Population with Keratoconus by Next-Generation Sequencing., PMID:35186329
Hsa_circRNA_0001971 contributes to oral squamous cell carcinoma progression via miR-186-5p/Fibronectin type III domain containing 3B axis., PMID:35060189
Identification of Circ-FNDC3B, an Overexpressed circRNA in Abdominal Aortic Aneurysm, as a Regulator of Vascular Smooth Muscle Cells., PMID:34789642
lncRNA LINC00355 Acts as a Novel Biomarker and Promotes Glioma Biological Activities via the Regulation of miR-1225/FNDC3B., PMID:34603558
Isoflurane upregulates microRNA-9-3p to protect rats from hepatic ischemia-reperfusion injury through inhibiting fibronectin type III domain containing 3B., PMID:34308776
Genetic predictors of sick sinus syndrome., PMID:34195885
Circular RNA circ_0006948 Promotes Esophageal Squamous Cell Carcinoma Progression by Regulating microRNA-3612/LASP1 Axis., PMID:34024023
CircSOS2 promotes cervical squamous cell carcinoma by regulation of proliferation, cell cycle, apoptosis, migration, invasion, and glycolysis by targeting miR-543/FNDC3B axis., PMID:34023283
Curcumin suppresses renal carcinoma tumorigenesis by regulating circ-FNDC3B/miR-138-5p/IGF2 axis., PMID:34001703
MicroRNA-363-3p promote the development of acute myeloid leukemia with RUNX1 mutation by targeting SPRYD4 and FNDC3B., PMID:33950983
Circ_0006948 Contributes to Cell Growth, Migration, Invasion and Epithelial-Mesenchymal Transition in Esophageal Carcinoma., PMID:33630215
Novel prognostic genes and subclasses of acute myeloid leukemia revealed by survival analysis of gene expression data., PMID:33536020
Expression of NR5A2, NUP153, HNF4A, USP15 and FNDC3B is consistent with their use as novel biomarkers for bovine mammary stem/progenitor cells., PMID:33400051
Novel lncRNA XLOC_032768 protects against renal tubular epithelial cells apoptosis in renal ischemia-reperfusion injury by regulating FNDC3B/TGF-β1., PMID:32972270
The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis., PMID:32966780
Natural display of nuclear-encoded RNA on the cell surface and its impact on cell interaction., PMID:32907628
CircFNDC3B sequestrates miR-937-5p to derepress TIMP3 and inhibit colorectal cancer progression., PMID:32896063
Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants., PMID:32473106
FNDC3B, Targeted by miR-125a-5p and miR-217, Promotes the Proliferation and Invasion of Colorectal Cancer Cells via PI3K/mTOR Signaling., PMID:32431508
Integrated Analysis of RNA-Binding Proteins in Glioma., PMID:32272554
For research use only. Not for human or drug use.
