Catalog No.
YHK73801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu290-Ser391
Predicted molecular weight
25.12 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92785
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein requiem, BAF45D, Zinc finger protein ubi-d4, BRG1-associated factor 45D, REQ, DPF2, UBID4, Apoptosis response zinc finger protein, D4, zinc and double PHD fingers family 2
Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization., PMID:39747661
DPF2 reads histone lactylation to drive transcription and tumorigenesis., PMID:39636855
The BAF complex enhances transcription through interaction with H3K56ac in the histone globular domain., PMID:39511190
More than three years' treatment response of recombinant human growth hormone in a patient with Coffin-Siris syndrome 7., PMID:39279315
DPF2 overexpression correlates with immune infiltration and dismal prognosis in hepatocellular carcinoma., PMID:39006087
Muscle-specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation., PMID:38837439
Alternative splicing of a chromatin modifier alters the transcriptional regulatory programs of stem cell maintenance and neuronal differentiation., PMID:38701759
DPF2-related Coffin-Siris syndrome type 7 in two generations., PMID:38697389
Muscle-Specific Pyruvate Kinase Isoforms, Pkm1 and Pkm2, Regulate Mammalian SWI/SNF Proteins and Histone 3 Phosphorylation During Myoblast Differentiation., PMID:38645038
Development of Complementary Photo-arginine/lysine to Promote Discovery of Arg/Lys hPTMs Interactomes., PMID:38298064
ARID2, a milder cause of Coffin-Siris Syndrome? Broadening the phenotype with 17 additional individuals., PMID:38243407
Transcriptome Profiling Based at Different Time Points after Hatching Deepened Our Understanding on Larval Growth and Development of Amphioctopus fangsiao., PMID:37623871
The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression., PMID:37200093
Machine learning-based predictive models and drug prediction for schizophrenia in multiple programmed cell death patterns., PMID:36993785
Congenital diaphragmatic hernia in Coffin Siris syndrome: Further evidence from two cases., PMID:36416235
Deciphering the Interactome of Histone Marks in Living Cells via Genetic Code Expansion Combined with Proximity Labeling., PMID:35862615
Evidence for an association between Coffin-Siris syndrome and congenital diaphragmatic hernia., PMID:35796094
A novel intragenic DPF2 deletion identified by genome sequencing in an adult with clinical features of Coffin-Siris syndrome., PMID:35607970
BAF45b Is Required for Efficient Zika Virus Infection of HAP1 Cells., PMID:34696437
Genotype-Phenotype Correlations in 208 Individuals with Coffin-Siris Syndrome., PMID:34205270
Rehabilitation in a rare case of coffin-siris syndrome with major cognitive and behavioural disorders., PMID:34180430
The DPF Domain As a Unique Structural Unit Participating in Transcriptional Activation, Cell Differentiation, and Malignant Transformation., PMID:33456978
BAF45D knockdown decreases cell viability, inhibits colony formation, induces cell apoptosis and S-phase arrest in human pancreatic cancer cells., PMID:32024442
A new missense mutation in DPF2 gene related to Coffin Siris syndrome 7: Description of a mild phenotype expanding DPF2-related clinical spectrum and differential diagnosis among similar syndromes epigenetically determined., PMID:31706665
Association of Basophil-Expressing Genes with Effectiveness of Sublingual Immunotherapy., PMID:31564689
Expanding the phenotypic spectrum associated with DPF2: A new case report., PMID:31207137
The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation., PMID:30609396
Mutational Landscapes and Phenotypic Spectrum of SWI/SNF-Related Intellectual Disability Disorders., PMID:30123105
SWI/SNF subunit expression heterogeneity in human aplastic anemia stem/progenitors., PMID:29596882
Mutations in the BAF-Complex Subunit DPF2 Are Associated with Coffin-Siris Syndrome., PMID:29429572
The aberrant splicing of BAF45d links splicing regulation and transcription in glioblastoma., PMID:29373718
Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations., PMID:28981154
DPFF-1 transcription factor deficiency causes the aberrant activation of MPK-1 and meiotic defects in the Caenorhabditis elegans germline., PMID:28940692
Tumor suppression via inhibition of SWI/SNF complex-dependent NF-κB activation., PMID:28924147
MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300., PMID:28580166
Histone-binding of DPF2 mediates its repressive role in myeloid differentiation., PMID:28533407
Double Plant Homeodomain Fingers 2 (DPF2) Promotes the Immune Escape of Influenza Virus by Suppressing Beta Interferon Production., PMID:28404846
Structural effects of sulfated polysaccharides from Codium fragile on NK cell activation and cytotoxicity., PMID:28130139
Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2., PMID:27775714
Data in support of DPF2 regulates OCT4 protein level and nuclear distribution., PMID:26958616
SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance., PMID:26571505
DPF2 regulates OCT4 protein level and nuclear distribution., PMID:26417682
Double PHD fingers protein DPF2 recognizes acetylated histones and suppresses the function of estrogen-related receptor α through histone deacetylase 1., PMID:25713408
Staufen1-mediated mRNA decay induces Requiem mRNA decay through binding of Staufen1 to the Requiem 3'UTR., PMID:24799437
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex., PMID:24332853
[D4 family genes in vertebrates: genomic organization and expression]., PMID:23659077
SS18 together with animal-specific factors defines human BAF-type SWI/SNF complexes., PMID:22442726
Double plant homeodomain (PHD) finger proteins DPF3a and -3b are required as transcriptional co-activators in SWI/SNF complex-dependent activation of NF-κB RelA/p50 heterodimer., PMID:22334708
Crystal structure of the Cys2His2-type zinc finger domain of human DPF2., PMID:21888896
For research use only. Not for human or drug use.
