Catalog No.
YHD96401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn106-Asn327
Predicted molecular weight
27.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P31689
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DnaJ protein homolog 2, DNAJA1, Heat shock protein J2, HDJ2, HSJ-2, HSJ2, HSPF4, Heat shock 40 kDa protein 4, HSDJ, DNAJ2, DnaJ homolog subfamily A member 1, Human DnaJ protein 2, hDj-2
Novel interaction with PSMD9 regulates DNAJA1 turnover and mitochondrial polarity., PMID:40412052
Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12., PMID:40113792
Physiological analysis and transcriptome sequencing revealed that HSPA1 was involved in response to heat stress in thick-shell mussels, Mytilus coruscus., PMID:40056693
Shared genes and relevant potential molecular linkages between COVID-19 and chronic thromboembolic pulmonary hypertension (CTEPH)., PMID:39891865
Identification and validation of a novel defined stress granule-related gene signature for predicting the prognosis of ovarian cancer via bioinformatics analysis., PMID:39809219
Polymorphism in Genes Encoding HSP40 Family Proteins is Associated with Ischemic Stroke Risk and Brain Infarct Size: A Pilot Study., PMID:39735968
Itaconate Ameliorates Experimental Autoimmune Uveitis by Modulating Teff/Treg Cell Imbalance Via the DNAJA1/CDC45 Axis., PMID:39661355
The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations., PMID:39618332
Integration of mRNA and miRNA Analysis Sheds New Light on the Muscle Response to Heat Stress in Spotted Sea Bass (Lateolabrax maculatus)., PMID:39596165
Interaction Network Characterization of Infectious Bronchitis Virus Nsp2 with Host Proteins., PMID:39591305
Enhanced homeostatic sleep response and decreased neurodegenerative proteins in cereblon knock-out mice., PMID:39349747
DNAJA1 regulates protein ubiquitination and is essential for spermatogenesis in the testes of mice and rats., PMID:39208916
Proteomics analysis for key molecules in adrenal glands of Wenchang chickens for their resistance to heat stress., PMID:39190996
Combination of transcriptomics and proteomics for analyzing potential biomarker and molecular mechanism underlying skeletal muscle atrophy., PMID:39179024
GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function., PMID:39018356
Type I Hsp40s/DnaJs aggregates exhibit features reminiscent of amyloidogenic structures., PMID:38975859
Dichotomous transactivation domains contribute to growth inhibitory and promotion functions of TAp73., PMID:38739802
Comprehensive profiling of endocrine metabolism identifies a novel signature with robust predictive value in ovarian cancer., PMID:38689382
DNAJA1‑knockout alleviates heat stroke‑induced endothelial barrier disruption via improving thermal tolerance and suppressing the MLCK‑MLC signaling pathway., PMID:38551163
Novel insights into the post-translational modifications of Ydj1/DNAJA1 co-chaperones., PMID:38309209
DNAJA1 positively regulates amino acid-stimulated milk protein and fat synthesis in bovine mammary epithelial cells., PMID:38269516
Genome-Wide Association Analysis of Heat Tolerance in F2 Progeny from the Hybridization between Two Congeneric Oyster Species., PMID:38203295
Upregulation of PD-1/PD-L1 and downregulation of immune signaling pathways lead to more severe visceral leishmaniasis in undernutrition mice., PMID:38185681
Vascular dysfunction caused by loss of Brn-3b/POU4F2 transcription factor in aortic vascular smooth muscle cells is linked to deregulation of calcium signalling pathways., PMID:38007517
DNAJA1 promotes proliferation and metastasis of breast cancer by activating mutant P53/NF-κB pathway., PMID:37977037
[Differential expression and implication of m6A methylation in mice with experimental myocardial infarction]., PMID:37963752
Human proteins curing yeast prions., PMID:37903258
Droj2 Facilitates Somatosensory Neurite Sculpting via GTP-Binding Protein Arf102F in Drosophila., PMID:37686022
DnaJA2 interacts with Japanese encephalitis virus NS3 via its C-terminal to promote viral infection., PMID:37633595
Dysregulation and oncogenic activities of ubiquitin specific peptidase 2a in the pathogenesis of hepatocellular carcinoma., PMID:37424823
A cytosolic surveillance mechanism activates the mitochondrial UPR., PMID:37286597
The stability and function of human cochaperone Hsp40/DNAJA1 are affected by zinc removal and partially restored by copper., PMID:37244380
Analysis of the Interactome of the Toxoplasma gondii Tgj1 HSP40 Chaperone., PMID:36976888
Shear Stress Markedly Alters the Proteomic Response to Hypoxia in Human Pulmonary Endothelial Cells., PMID:36730645
The roles of HSP40/DNAJ protein family in neurodegenerative diseases., PMID:36581576
A pathological role of the Hsp40 protein Ydj1/DnaJA1 in models of Alzheimer's disease., PMID:36448030
ATP7B-Deficient Hepatocytes Reveal the Importance of Protein Misfolding Induced at Low Copper Concentration., PMID:36359796
Ameliorative effect of the oil components derived from sweet potato shochu on impaired short-term memory in mice after amyloid β25-35 injection., PMID:36336574
DNAJA1- and conformational mutant p53-dependent inhibition of cancer cell migration by a novel compound identified through a virtual screen., PMID:36316326
Next Generation Sequencing of Genotype Variants and Genetic Association between Heat Shock Proteins HSPA1B Single Nucleotide Polymorphism at the g.31829044 Locus and Heat Tolerance: A Pilot Quasi-Experimental Study., PMID:36291674
Leveraging the Structure of DNAJA1 to Discover Novel Potential Pancreatic Cancer Therapies., PMID:36291603
Druggable sites/pockets of the p53-DNAJA1 protein-protein interaction: In silico modeling and in vitro/in vivo validation., PMID:36220282
Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin., PMID:36077724
Construction of the coexpression network involved in the pathogenesis of thyroid eye disease via bioinformatics analysis., PMID:36076300
Porcine Circovirus type 2 infected myocardial tissue transcriptome signature., PMID:35714796
Structural resemblance of the DNAJA-family protein, Tid1, to the DNAJB-family Hsp40., PMID:35651334
DNAJA1 Stabilizes EF1A1 to Promote Cell Proliferation and Metastasis of Liver Cancer Mediated by miR-205-5p., PMID:35586205
BAG1, MGMT, FOXO1, and DNAJA1 as potential drug targets for radiosensitizing cancer cell lines., PMID:35511481
The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity., PMID:35373908
Identification of epilepsy concomitant candidate genes recognized in Saudi epileptic patients., PMID:35363364
For research use only. Not for human or drug use.
