Catalog No.
YHK73701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Thr102
Predicted molecular weight
25.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BW61
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Placenta cross-immune reaction antigen 1, PCIA1, PCIA-1, C19orf58, DDA1, DET1- and DDB1-associated protein 1
DET1 dynamics underlie cooperative ubiquitination by CRL4DET1-COP1 complexes., PMID:40009677
Impairment of DET1 causes neurological defects and lethality in mice and humans., PMID:39937864
Hormone-mediated disassembly and inactivation of a plant E3 ubiquitin ligase complex., PMID:39365702
The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics., PMID:39075067
Social setting interacts with hyper dopamine to boost the stimulant effect of ethanol., PMID:38898729
Native mass spectrometry of complexes formed by molecular glues reveals stoichiometric rearrangement of E3 ligases., PMID:38639441
DDA1, a novel factor in transcription-coupled repair, modulates CRL4CSA dynamics at DNA damage-stalled RNA polymerase II., PMID:37886519
Integrative exploration of the mutual gene signatures and immune microenvironment between benign prostate hyperplasia and castration-resistant prostate cancer., PMID:36974949
Dihydroartemisinin Affects STAT3/DDA1 Signaling Pathway and Reverses Breast Cancer Resistance to Cisplatin., PMID:36891981
Innate and learned odor-guided behaviors utilize distinct molecular signaling pathways in a shared dopaminergic circuit., PMID:36701232
Discovery of novel DNA-damaging agents through phenotypic screening for DNA double-strand break., PMID:36385507
Integrated Omics analysis of pig muscle metabolism under the effects of dietary Chlorella vulgaris and exogenous enzymes., PMID:36216870
Genetic and compound screens uncover factors modulating cancer cell response to indisulam., PMID:35534224
Prediction of breast cancer proteins involved in immunotherapy, metastasis, and RNA-binding using molecular descriptors and artificial neural networks., PMID:32444848
A mutation in the essential and widely conserved DAMAGED DNA BINDING1-Cullin4 ASSOCIATED FACTOR gene OZS3 causes hypersensitivity to zinc excess, cold and UV stress in Arabidopsis thaliana., PMID:32314481
Concerted Actions of Octopamine and Dopamine Receptors Drive Olfactory Learning., PMID:32277043
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex., PMID:31819272
Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820., PMID:31693911
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15., PMID:31686031
LncRNA HOTTIP promotes proliferation and cell cycle progression of acute myeloid leukemia cells., PMID:31002141
DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis., PMID:30192741
Dopamine Receptor DAMB Signals via Gq to Mediate Forgetting in Drosophila., PMID:29166600
The mushroom body D1 dopamine receptor controls innate courtship drive., PMID:28902472
Involvement of DPP9 in gene fusions in serous ovarian carcinoma., PMID:28893231
Behavioral Sensitization to the Disinhibition Effect of Ethanol Requires the Dopamine/Ecdysone Receptor in Drosophila., PMID:28824387
Genome-scale transcriptional analysis reveals key genes associated with the development of type II diabetes in mice., PMID:28450939
DDA1 is induced by NR2F6 in ovarian cancer and predicts poor survival outcome., PMID:28387912
DDA1, a novel oncogene, promotes lung cancer progression through regulation of cell cycle., PMID:28211159
Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase., PMID:28087699
DDA1 promotes stage IIB-IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling., PMID:26942699
Targeted degradation of abscisic acid receptors is mediated by the ubiquitin ligase substrate adaptor DDA1 in Arabidopsis., PMID:24563205
Breaking "bad" proteins to modulate abscisic acid signaling., PMID:24563200
Dopamine is required for learning and forgetting in Drosophila., PMID:22578504
Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response., PMID:22072767
Sleep deprivation during early-adult development results in long-lasting learning deficits in adult Drosophila., PMID:21286249
Misregulation of the LOB domain gene DDA1 suggests possible functions in auxin signalling and photomorphogenesis., PMID:20797997
Differential treatment regimen-related effects of cannabinoids on D1 and D2 receptors in adolescent and adult rat brain., PMID:20673846
Genetic characterization of HIV type 1 among patients with suspected immune reconstitution inflammatory syndrome after initiation of antiretroviral therapy in Kenya., PMID:20624074
Persistent short-term memory defects following sleep deprivation in a drosophila model of Parkinson disease., PMID:19725249
An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases., PMID:19295130
The GABAA receptor RDL suppresses the conditioned stimulus pathway for olfactory learning., PMID:19193904
Drosophila D1 dopamine receptor mediates caffeine-induced arousal., PMID:19074291
D1 receptor activation in the mushroom bodies rescues sleep-loss-induced learning impairments in Drosophila., PMID:18674913
Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development., PMID:18606781
Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection., PMID:18464893
D1 dopamine receptor dDA1 is required in the mushroom body neurons for aversive and appetitive learning in Drosophila., PMID:17634358
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymes., PMID:17452440
Ap-let neurons--a peptidergic circuit potentially controlling ecdysial behavior in Drosophila., PMID:15081360
Expression of a D1 dopamine receptor dDA1/DmDOP1 in the central nervous system of Drosophila melanogaster., PMID:12711555
The selector gene cut represses a neural cell fate that is specified independently of the Achaete-Scute-Complex and atonal., PMID:11429282
For research use only. Not for human or drug use.
