Catalog No.
YHK73601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu32-Asp224
Predicted molecular weight
23.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9GZQ3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COMM domain-containing protein 5, Hypertension-related calcium-regulated gene protein, HCaRG, COMMD5
Contrasting Role of COMMD5 in Renal Cell Carcinoma: Tumor Suppression and Metastatic Enhancement., PMID:40155026
COMMD5 is involved in the mechanisms of hypotension after parathyroidectomy in patients receiving hemodialysis., PMID:36804542
COMMD5 Inhibits Malignant Behavior of Renal Cancer Cells., PMID:34083270
Does Subtelomeric Position of COMMD5 Influence Cancer Progression?, PMID:33768002
COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking., PMID:30021164
COMMD9 promotes TFDP1/E2F1 transcriptional activity via interaction with TFDP1 in non-small cell lung cancer., PMID:27871936
Genome-Wide Association Study of Cell-Mediated Response in Dogs Naturally Infected by Leishmania infantum., PMID:27736777
Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling., PMID:26553930
Hypertension-related, calcium-regulated gene (HCaRG/COMMD5) and kidney diseases: HCaRG accelerates tubular repair., PMID:24515317
HCaRG accelerates tubular repair after ischemic kidney injury., PMID:21921141
Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression., PMID:18949406
HCaRG increases renal cell migration by a TGF-alpha autocrine loop mechanism., PMID:16033922
HCaRG is a novel regulator of renal epithelial cell growth and differentiation causing G2M arrest., PMID:12620924
Chromosomal mapping of HCaRG, a novel hypertension-related, calcium-regulated gene., PMID:11871861
HCaRG, a novel calcium-regulated gene coding for a nuclear protein, is potentially involved in the regulation of cell proliferation., PMID:10918053