Catalog No.
YHK73501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu736-Leu1146
Predicted molecular weight
50.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9P2M7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA1319, Cingulin, CGN
Study on the mechanism of acteoside in treating purinomycin aminonucleoside-induced chronic glomerulonephritis in childhood rats based on Cxcr4-PI3K-Akt-eNOS axis., PMID:40389008
Integrating proteomics and network pharmacology to explore the relevant mechanism of Huangkui capsule in the treatment of chronic glomerulonephritis., PMID:40356949
Targeted genotyping (90K-SPET) facilitates genome-wide association studies and the prediction of yield-related traits in faba bean (Vicia faba L.)., PMID:40301715
Effect of heat stress on ileal epithelial barrier integrity in broilers divergently selected for high- and low-water efficiency., PMID:40260206
Renal expression and clinical significance of Bach1-related oxidative stress indicators in patients with chronic glomerulonephritis., PMID:40186888
Inhibition of METTL3 promotes mesangial cell mitophagy and attenuates glomerular damage by alleviating FOSL1 m6A modifications via IGF2BP2-dependent mechanisms., PMID:40081768
Effect of Food Matrix on Regulation of Intestinal Barrier and Microbiota Homeostasis by Polysaccharides Sulfated Carrageenan., PMID:40002079
Encapsulated hesperetin modulates inflammatory responses in an in vitro intestinal immune co-culture model., PMID:39986769
Plasma proteins are integral to gene-regulatory networks acting within and across blood cells, the arterial wall and major metabolic organs., PMID:39973987
Gut Microbiota-Mediated Degradation of Food-Grade Lambda-Carrageenan by Bacteroides xylanisolvens and Its Role in Inflammation., PMID:39920146
GWAS Identifies SNP Markers and Candidate Genes for Off-Flavours and Protein Content in Faba Bean (Vicia faba L.)., PMID:39861546
Behavioral Test Scores Could Be Linked to the Protein Expression Values of p62 and GLAST in the Brains of Mice with Neuropsychiatric Disorder-Related Behaviors., PMID:39765706
Rostellularia procumbens (L) Nees. extract attenuates adriamycin-induced nephropathy by maintaining mitochondrial dynamics balance via SIRT1/PGC-1α signaling pathway activation., PMID:39733803
Plasma phosphorylated tau and neuropsychiatric symptoms in dementia with Lewy bodies., PMID:39732510
Dietary Carrageenan Amplifies the Inflammatory Profile, but not Permeability, of Intestinal Epithelial Cells from Patients With Crohn's Disease., PMID:39720875
Sex and APOE ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease., PMID:39711105
Transfer of miR-100 and miR-125b increases 3D growth and invasiveness in recipient cancer cells., PMID:39697634
Synthesis and Characterization of Transferrin and Cell-Penetrating Peptide-Functionalized Liposomal Nanoparticles to Deliver Plasmid ApoE2 In Vitro and In Vivo in Mice., PMID:39665408
BTK regulates microglial function and neuroinflammation in human stem cell models and mouse models of multiple sclerosis., PMID:39578444
The role of METTL3-mediated CircStk4 modification in the treatment of chronic glomerulonephritis with Qi Teng Xiao Zhuo granule., PMID:39488875
Targeting of oxidized Macrophage Migration Inhibitory Factor (oxMIF) with antibody ON104 attenuates the severity of glomerulonephritis., PMID:39374239
Cingulin-nonmuscle myosin interaction plays a role in epithelial morphogenesis and cingulin nanoscale organization., PMID:39319625
Genome binding properties of Zic transcription factors underlie their changing functions during neuronal maturation., PMID:39218853
Genomic factors shaping codon usage across the Saccharomycotina subphylum., PMID:39213398
Mechanistic insights into a heterobifunctional degrader-induced PTPN2/N1 complex., PMID:39152201
[Anemia of chronic diseases in the early stages of chronic kidney disease as a risk factor for cardiovascular complications in patients with glomerulonephritis]., PMID:39106502
A human-specific cytotoxic neopeptide generated by the deafness gene Cingulin., PMID:39098598
Discordant Phenotypes of Nephritis in Patients with X-linked Agammaglobulinemia., PMID:39052129
Circular E3 ubiquitin-protein ligase improves renal function and alleviates inflammation and renal injury in chronic glomerulonephritis rats via the microRNA-146a-5p / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma axis., PMID:39042393
Doxorubicin as a Drug Repurposing for Disruption of α-Chymotrypsinogen-A Aggregates., PMID:39014260
Electrophysiology of Human iPSC-derived Vascular Smooth Muscle Cells and Cell-autonomous Consequences of Cantú Syndrome Mutations., PMID:38984978
Mesangial cell-derived CircRNAs in chronic glomerulonephritis: RNA sequencing and bioinformatics analysis., PMID:38946402
Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias., PMID:38905635
Macrophage-derived macrophage migration inhibitory factor mediates renal injury in anti-glomerular basement membrane glomerulonephritis., PMID:38846956
miR-100 and miR-125b Contribute to Enhanced 3D Growth and Invasiveness and can be Functionally Transferred to Silence Target Genes in Recipient Cells., PMID:38826470
The roles of tight junction protein cingulin in human endometrioid endometrial cancer., PMID:38825958
Identification of an Immunodominant B-Cell Epitope in African Swine Fever Virus p30 Protein and Evidence of p30 Antibody-Mediated Antibody Dependent Cellular Cytotoxicity., PMID:38793639
Arginines of the CGN codon family are Achilles' heels of cancer genes., PMID:38778164
Unveiling the rheological and thermal behavior of a novel Salecan and whey protein isolate composite gel., PMID:38777009
Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis., PMID:38639096
Neuroprotective Effect of Sterculia setigera Leaves Hydroethanolic Extract., PMID:38630337
Junctional Adhesion Molecule (JAM)-C recruitment of Pard3 and drebrin to cell contacts initiates neuron-glia recognition and layer-specific cell sorting in developing cerebella., PMID:38585827
Genetic associations of protein-coding variants in venous thromboembolism., PMID:38561338
Inhibition of ALKBH5 inhibits inflammation and excessive proliferation by promoting TRIM13 m6A modifications in glomerular mesangial cells., PMID:38536435
MS4A6D Promotes carrageenan-induced footpad swelling in mice through enhancing macrophages-derived inflammation., PMID:38493579
Methotrexate for Drug Repurposing as an Anti-Aggregatory Agent to Mercuric Treated α-Chymotrypsinogen-A., PMID:38431536
Tight junction protein cingulin variant is associated with cancer susceptibility by overexpressed IQGAP1 and Rac1-dependent epithelial-mesenchymal transition., PMID:38424547
The Roles and Regulatory Mechanisms of Tight Junction Protein Cingulin and Transcription Factor Forkhead Box Protein O1 in Human Lung Adenocarcinoma A549 Cells and Normal Lung Epithelial Cells., PMID:38338691
METTL3 modification of circStk4 affects mouse glomerular messangial cell autophagy, proliferation and apotosis by regulating miR-133a-3p/C1 axis., PMID:38331014
A novel scale for triage assessment of frailty in the emergency department (ED-FraS): a prospective videotaped study., PMID:38321397
For research use only. Not for human or drug use.
