Catalog No.
YHH53101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg233-Gly341
Predicted molecular weight
25.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q2TAZ0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Autophagy-related protein 2 homolog A, ATG2A, KIAA0404
SETD5-Coordinated LC3B Methylation Inhibits Autophagy in Ovarian Cancer., PMID:40497358
[Transcriptomic analysis of suspended Vero cells and reduction of cellular autophagy by epidermal growth factor]., PMID:40328724
ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis., PMID:40196537
S-palmitoylation modulates ATG2-dependent non-vesicular lipid transport during starvation-induced autophagy., PMID:40128367
ATG2A-WDR45/WIPI4-ATG9A complex-mediated lipid transfer and equilibration during autophagosome formation., PMID:40116844
ATG2A acts as a tether to regulate autophagosome-lysosome fusion in neural cells., PMID:40083067
Polymyxin B induces pigmentation by upregulating ATG2A-ERK/CREB-MITF-PMEL17 signaling axis., PMID:40074142
Effect and mechanism of miRNA-144-5p-regulated autophagy in older adults with Sarcopenia., PMID:39953589
Determining ATG2 Localization During Autophagosome Formation in Mammalian Cells., PMID:39699732
A methodology for gene level omics-WAS integration identifies genes influencing traits associated with cardiovascular risks: the Long Life Family Study., PMID:39276247
Transcriptomic Analysis of Metformin's Effect on Bovine Viral Diarrhea Virus Infection., PMID:39195830
Structural basis for lipid transfer by the ATG2A-ATG9A complex., PMID:39174844
[Knockdown mitochondrial transcription factor A (TFAM) inhibits autophagy, proliferation, invasion and migration in human cervical cancer and osteosarcoma cells]., PMID:38710515
ANKFY1 bridges ATG2A-mediated lipid transfer from endosomes to phagophores., PMID:38622126
Multi-omics Integration Identifies Genes Influencing Traits Associated with Cardiovascular Risks: The Long Life Family Study., PMID:38496585
Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis., PMID:38454050
The Role of Rv1476 in Regulating Stress Response and Intracellular Survival of Mycobacterium tuberculosis., PMID:38392218
Exploring the ATG9A interactome uncovers interaction with VPS13A., PMID:38294121
The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy., PMID:38077022
Coiled-coil-mediated dimerization of Atg16 is required for binding to the PROPPIN Atg21., PMID:37989223
ATG9B is a tissue-specific homotrimeric lipid scramblase that can compensate for ATG9A., PMID:37938170
Distinct roles of core autophagy-related genes in zebrafish definitive hematopoiesis., PMID:37921505
ATG9A supports Chlamydia trachomatis infection via autophagy-independent mechanisms., PMID:37707289
ATG2A-mediated bridge-like lipid transport regulates lipid droplet accumulation., PMID:37645754
HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy., PMID:37463911
MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy., PMID:37460467
Tracking the transition from an ATG9A vesicle to an autophagosome., PMID:37405380
Metamorphosis by ATG13 and ATG101 in human autophagy initiation., PMID:37394799
Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation., PMID:37115157
ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation., PMID:36347259
Mesenchymal stem cells-derived HIF-1α-overexpressed extracellular vesicles ameliorate hypoxia-induced pancreatic β cell apoptosis and senescence through activating YTHDF1-mediated protective autophagy., PMID:36244321
MicroRNA-378 contributes to osteoarthritis by regulating chondrocyte autophagy and bone marrow mesenchymal stem cell chondrogenesis., PMID:35474736
Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression., PMID:35253629
Beclin-1/LC3-II dependent macroautophagy was uninfluenced in ischemia-challenged vascular endothelial cells., PMID:35224166
Loss of Profilin3 Impairs Spermiogenesis by Affecting Acrosome Biogenesis, Autophagy, Manchette Development and Mitochondrial Organization., PMID:34869336
Ischemia-Challenged human umbilical vascular endothelial cells: Proteomics data., PMID:34136594
WDR45 Mutation Impairs the Autophagic Degradation of Transferrin Receptor and Promotes Ferroptosis., PMID:34012978
Minimized combinatorial CRISPR screens identify genetic interactions in autophagy., PMID:33956155
A model for a partnership of lipid transfer proteins and scramblases in membrane expansion and organelle biogenesis., PMID:33850023
β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells., PMID:33636118
HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation., PMID:33619246
Compulsive methamphetamine taking induces autophagic and apoptotic markers in the rat dorsal striatum., PMID:32676729
Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery., PMID:32610138
Multi-site-mediated entwining of the linear WIR-motif around WIPI β-propellers for autophagy., PMID:32483132
A conserved ATG2-GABARAP family interaction is critical for phagophore formation., PMID:32009292
miR-541 potentiates the response of human hepatocellular carcinoma to sorafenib treatment by inhibiting autophagy., PMID:31727683
Human ATG2B possesses a lipid transfer activity which is accelerated by negatively charged lipids and WIPI4., PMID:31721365
ATG2 regulation of phagophore expansion at mitochondria-associated ER membranes., PMID:31512567
ATG2A transfers lipids between membranes in vitro., PMID:31441376
TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion., PMID:31412244
For research use only. Not for human or drug use.
