Catalog No.
YHC37101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala40-Glu425
Predicted molecular weight
46.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P08910
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Monoacylglycerol lipase ABHD2, ABHD2, LABH2, Protein PHPS1-2, 2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 2, Acetylesterase, Lung alpha/beta hydrolase 2, Progesterone-sensitive lipase
MSI1 Accelerates Prostate Cancer Cell Proliferation, Migration and Glycolysis by Promoting ABHD2 Transcription., PMID:40067652
Progesterone induces meiosis through two obligate co-receptors with PLA2 activity., PMID:39873665
Unveiling therapeutic biomarkers and druggable targets in ALS: An integrative microarray analysis, molecular docking, and structural dynamic studies., PMID:39299050
Novel circular RNA hsa_circ_0036683 suppresses proliferation and migration by mediating the miR-4664-3p/CDK2AP2 axis in non-small cell lung cancer., PMID:39113208
Caspase-9 Is a Positive Regulator of Osteoblastic Cell Migration Identified by diaPASEF Proteomics., PMID:38498986
Abhd2, a Candidate Gene Regulating Airway Remodeling in COPD via TGF-β., PMID:38197032
ABHD2 deficiency aggravates ovalbumin-induced airway remodeling through the PI3K/Akt pathway in an animal model of chronic asthma., PMID:38088307
Progesterone induces meiosis through two obligate co-receptors with PLA2 activity., PMID:37905030
Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin., PMID:37523383
Membrane Cholesterol Inhibits Progesterone-Mediated Sperm Function through the Possible Involvement of ABHD2., PMID:37298205
A comparative mRNA- and miRNA transcriptomics reveals novel molecular signatures associated with metastatic prostate cancers., PMID:36468011
Many or too many progesterone membrane receptors? Clinical implications., PMID:36384863
Radiometric Assay of ABHD2 Activity., PMID:36152197
Vaspin accelerates the proliferation, invasion and metastasis of Triple-Negative breast cancer through MiR-33a-5p/ABHD2., PMID:36125462
TDP-43 upregulates lipid metabolism modulator ABHD2 to suppress apoptosis in hepatocellular carcinoma., PMID:35963893
Gain of GAS5 reveals worse prognosis in kidney renal clear cell carcinoma and liver hepatocellular carcinoma from the Cancer Genome Atlas dataset., PMID:35116254
Alpha/Beta Hydrolase Domain-Containing Protein 2 Regulates the Rhythm of Follicular Maturation and Estrous Stages of the Female Reproductive Cycle., PMID:34568325
Progesterone activates the cyclic AMP-protein kinase A signalling pathway by upregulating ABHD2 in fertile men., PMID:33752482
Circular RNA circ_0079593 enhances malignant melanoma progression by the regulation of the miR-573/ABHD2 axis., PMID:33648800
Affecting Lipid Metabolism Salivary MicroRNAs Expressions in Arabian Racehorses Before and After the Race., PMID:32972679
Novel insights into wound age estimation: combined with "up, no change, or down" system and cosine similarity in python environment., PMID:32909067
miR-4454 up-regulated by HPV16 E6/E7 promotes invasion and migration by targeting ABHD2/NUDT21 in cervical cancer., PMID:32816024
Semen Modulates the Expression of NGF, ABHD2, VCAN, and CTEN in the Reproductive Tract of Female Rabbits., PMID:32645906
CARMAL Is a Long Non-coding RNA Locus That Regulates MFGE8 Expression., PMID:32625236
ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction., PMID:31697462
Characterisation and localisation of the endocannabinoid system components in the adult human testis., PMID:31537814
ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction., PMID:31525885
Retinoic Acid Induces Differentiation of Mouse F9 Embryonic Carcinoma Cell by Modulating the miR-485 Targeting of Abhd2., PMID:31035455
Regulation of MFGE8 by the intergenic coronary artery disease locus on 15q26.1., PMID:30861420
Asymmetrically Positioned Flagellar Control Units Regulate Human Sperm Rotation., PMID:30184496
Weighted Gene Co-Expression Network Analysis Identifies Specific Modules and Hub Genes Related to Hyperlipidemia., PMID:30045016
Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1., PMID:28813576
Regulation of calcium release from the endoplasmic reticulum by the serine hydrolase ABHD2., PMID:28684316
Regulation of the sperm calcium channel CatSper by endogenous steroids and plant triterpenoids., PMID:28507119
Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer., PMID:27323405
Identification of PSD-95 Depalmitoylating Enzymes., PMID:27307232
Molecular characterization of human ABHD2 as TAG lipase and ester hydrolase., PMID:27247428
Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone., PMID:26989199
Abhydrolase domain containing 2, an androgen target gene, promotes prostate cancer cell proliferation and migration., PMID:26854828
Associations of ABHD2 genetic variations with risks for chronic obstructive pulmonary disease in a Chinese Han population., PMID:25880496
Finding genes discriminating smokers from non-smokers by applying a growing self-organizing clustering method to large airway epithelium cell microarray data., PMID:23534707
Antisense oligonucleotides targeting abhydrolase domain containing 2 block human hepatitis B virus propagation., PMID:21466387
Age-related pulmonary emphysema in mice lacking alpha/beta hydrolase domain containing 2 gene., PMID:19250629
Elevated mature macrophage expression of human ABHD2 gene in vulnerable plaque., PMID:17980156
Whole genome expression profiling of hepatitis B virus-transfected cell line reveals the potential targets of anti-HBV drugs., PMID:17505500
Homozygous deletion related to Alu repeats in RLBP1 causes retinitis punctata albescens., PMID:17065479
Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers., PMID:16380080
Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice., PMID:15750623
Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha/beta hydrolase domain containing 2 gene., PMID:15721306
Cloning and tissue distribution of three murine alpha/beta hydrolase fold protein cDNAs., PMID:11922611
For research use only. Not for human or drug use.
