Catalog No.
YHF51001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser175
Predicted molecular weight
22.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P62330
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ARF6, ADP-ribosylation factor 6
Methuosis key gene ARF6 as a diagnostic, prognostic and immunotherapeutic marker for prostate cancer: based on a comprehensive pan-cancer multi-omics analysis., PMID:40410613
Protein S-glutathionylation confers cellular resistance to ferroptosis induced by glutathione depletion., PMID:40354766
EFA6A, a Guanine Nucleotide Exchange Factor for Arf6, Regulates Developmental Stage-Dependent Spine Morphogenesis, Synaptic Plasticity, and Long-Term Memory in the Hippocampus., PMID:40335791
Silencing of Rac1 and Arf6 reduces time-dependent and carbachol-induced contractions, proliferation, survival and growth in human bladder smooth muscle cells., PMID:40332567
Relationship between autoimmunity and COPD: an investigation based on proteomic profiling and antinuclear antibody screening., PMID:40329569
O-Fucosyltransferase SPINDLY attenuates auxin-induced fruit growth by inhibiting ARF6/8-coactivator mediator complex interaction in Arabidopsis., PMID:40295503
ARF6 Promotes AML Progression via Activation of PI3K/AKT/mTOR Signaling., PMID:40275490
Acute aerobic exercise alters serum protein distribution in colorectal cancer patients., PMID:40270615
Structural elucidation of how ARF small GTPases induce membrane tubulation for vesicle fission., PMID:40117306
The calcium pump PMCA4b promotes epithelial cell polarization and lumen formation., PMID:40075218
PISAD: De novo peptide design for target protein with iterative stochastic searching algorithm and docking assessment., PMID:40054153
miR-145-5p Inhibits HER2-Positive Breast Cancer Cells via Targeting ARF6., PMID:40046454
The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles., PMID:39977325
GULP1 as a Novel Diagnostic and Predictive Biomarker in Hepatocellular Carcinoma., PMID:39914372
Spatiotemporal distribution of PKCα, PIP3, Moesin, Cdc42, MARCKS, Scriblle, and Arf6 before directed cell migration in monolayers., PMID:39892054
Global identification and regulatory network analysis reveal the significant roles of lncRNAs during anther and pollen development in Arabidopsis., PMID:39883185
ArfGAP with the SH3 Domain, Ankyrin Repeat and PH Domain 1 Inversely Regulates Programmed Death-Ligand 1 Through Negative Feedback of Phosphorylated Epithelial Growth Factor Receptor and Activation of Nuclear Factor-Kappa B in Non-Small Cell Lung Cancer., PMID:39866192
Dietary limonin alleviates Salmonella Typhimurium-induced colitis via dual targeting virulence SopB and SopE2 and inhibiting RAC1/CDC42/Arp2/3 pathway and regulating gut microbiota., PMID:39820212
miR-28-3p suppresses gastric cancer growth and EMT-driven metastasis by targeting the ARF6/Hedgehog axis., PMID:39788390
Kupffer Cell-derived IL6 Promotes Hepatocellular Carcinoma Metastasis Via the JAK1-ACAP4 Pathway., PMID:39744421
Ginsenoside Ro improves Salmonella Typhimurium-induced colitis through inhibition of the virulence factors SopB and SopE2 via the RAC1/CDC42/ARP2/3 pathway., PMID:39734277
Plasticity and Tumor Microenvironment in Pancreatic Cancer: Genetic, Metabolic, and Immune Perspectives., PMID:39682280
β-elemene Ameliorates Cisplatin Resistance of Gastric Cancer via Regulating Exosomal METTL3-m6A-ARF6 Axis., PMID:39602058
Endothelial Dysfunction in Pulmonary Hypertension: Does ADP Ribosylation Factor 6-mediated HIF-2α Stabilization Matter?, PMID:39565185
ARF6 as a Novel Activator of HIF-2α in Pulmonary Arterial Hypertension., PMID:39556110
Bcl2l12, a novel protein interacting with Arf6, triggers Schwann cell differentiation programme., PMID:39510036
Reconstitution of Rab11-FIP4 Expression Rescues Cellular Homeostasis in Cystinosis., PMID:39434668
Conformational analysis of the IQSEC2 protein by statistical thermodynamics., PMID:39431217
Semaphorin 3D promotes pancreatic ductal adenocarcinoma progression and metastasis through macrophage reprogramming., PMID:39413197
The p. S178L mutation in Tbc1d24 disrupts endosome-mediated synaptic vesicle trafficking of cochlear hair cells and leads to hearing impairment in mice., PMID:39400345
Proximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion., PMID:39232006
Localization of EFA6A, an exchange factor for Arf6, in Z-lines and sarcoplasmic reticulum membranes in addition to myofilaments in I-domains of skeletal myofibers of peri-natal mice., PMID:39126836
Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy., PMID:39098861
[HRV16 inhibits bacterial clearance in a ARL5b-dependent manner]., PMID:38986089
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics., PMID:38902252
Arf6 GTPase deficiency leads to porcine oocyte quality decline during aging., PMID:38884157
dAsap regulates cellular protrusions via an Arf6-dependent actin regulatory pathway in S2R+ cells., PMID:38862211
Preliminary Study on Clinical Characteristics and Pathogenesis of IQSEC2 Mutations Patients., PMID:38827181
CD24 promotes metastasis and chemoresistance by directly targeting Arf6-ERK pathway in esophageal squamous cell carcinoma., PMID:38801885
Small GTPases control macropinocytosis of amyloid precursor protein and cleavage to amyloid-β., PMID:38799759
EFA6A, an Exchange Factor for Arf6, Regulates NGF-Dependent TrkA Recycling From Early Endosomes and Neurite Outgrowth in PC12 Cells., PMID:38725127
Association of ADP‑ribosylation factor family genes with prognosis and immune infiltration of breast cancer., PMID:38699662
Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5., PMID:38679330
ARF6 promotes Streptococcus suis suilysin induced apoptosis in HBMECs., PMID:38663699
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis., PMID:38648480
Pan-cancer analysis of ARFs family and ARF5 promoted the progression of hepatocellular carcinoma., PMID:38617932
Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice., PMID:38545783
Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging., PMID:38519806
A neurodevelopmental disorder associated with a loss-of-function missense mutation in RAB35., PMID:38432637
Novel oncogenic transcriptional targets of mutant p53 in esophageal squamous cell carcinoma., PMID:38358025
For research use only. Not for human or drug use.
