Catalog No.
YHB69401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys581-Lys720
Predicted molecular weight
18.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95573
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LACS 3, LACS3, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 3, ACS3, Long-chain-fatty-acid--CoA ligase 3, FACL3, ACSL3
Exosomal miR-196a-5p Secreted by Bone Marrow Mesenchymal Stem Cells Inhibits Ferroptosis and Promotes Drug Resistance of Acute Myeloid Leukemia., PMID:40388337
Proteome of granulosa cells lipid droplets reveals mechanisms regulating lipid metabolism at hierarchical and pre-hierarchical follicle in goose., PMID:40230795
The Expression of Ferroptosis-Related Genes in Hepatocellular Carcinoma and Their Relationships With Prognosis., PMID:40130081
Hypercholesterolemia-induced LXR signaling in smooth muscle cells contributes to vascular lesion remodeling and visceral function., PMID:40035761
Bioinformatics insights into ACSL1 and ACSL5: prognostic and immune roles in low-grade glioma., PMID:39924494
Lipid Metabolism Related Gene ACSL3 as a Biomarker for Predicting Immunotherapy Outcomes in Lung Adenocarcinoma., PMID:39842163
TNFAIP3 affects ferroptosis after traumatic brain injury by affecting the deubiquitination and ubiquitination pathways of the HMOX1 protein and ACSL3., PMID:39743027
Core promoter identification and transcriptional regulation of porcine ACSL3 gene., PMID:39584470
Effects of Essential Oil Blends Supplementation on Growth Performance, Meat Physiochemical Parameters, Intestinal Health and Lipid Metabolism of Weaned Bamei Piglets., PMID:39567854
ACSL3 is a promising therapeutic target for alleviating anxiety and depression in Alzheimer's disease., PMID:39532829
Clog P-Guided Development of Multi-Colored Buffering Fluorescent Probes for Super-Resolution Imaging of Lipid Droplet Dynamics., PMID:39475001
Identification and Functional Characterization of the FATP1 Gene from Mud Crab, Scylla paramamosain., PMID:39457899
Rice Protein Peptides Alleviate Alcoholic Liver Disease via the PPARγ Signaling Pathway: Through Liver Metabolomics and Gut Microbiota Analysis., PMID:39406388
IL15RA-STAT3-GPX4/ACSL3 signaling leads to ferroptosis resistance in pancreatic cancer., PMID:39396119
ANKRD1 aggravates renal ischaemia‒reperfusion injury via promoting TRIM25-mediated ubiquitination of ACSL3., PMID:39285846
Acyl-CoA Synthetase Long-Chain Isoenzymes in Kidney Diseases: Mechanistic Insights and Therapeutic Implications., PMID:39210707
Discovering the lipid metabolism-related hub genes of HCC-treated samples with PPARα agonist through weighted correlation network analysis., PMID:39179766
METTL3 in cancer-associated fibroblasts-derived exosomes promotes the proliferation and metastasis and suppresses ferroptosis in colorectal cancer by eliciting ACSL3 m6A modification., PMID:39160584
Vitamin B5 is a context-dependent dietary regulator of nociception., PMID:39073591
ACSL3 regulates breast cancer progression via lipid metabolism reprogramming and the YES1/YAP axis., PMID:38953696
G6PD and ACSL3 are synthetic lethal partners of NF2 in Schwann cells., PMID:38879607
Exploring the ATG9A interactome uncovers interaction with VPS13A., PMID:38294121
The translational potential of miR-26 in atherosclerosis and development of agents for its target genes ACC1/2, COL1A1, CPT1A, FBP1, DGAT2, and SMAD7., PMID:38195542
Ferrostatin-1 attenuates hypoxic-ischemic brain damage in neonatal rats by inhibiting ferroptosis., PMID:38130589
Identification of postnatal development dependent genes and proteins in porcine epididymis., PMID:38049726
FTO Sensitizes Oral Squamous Cell Carcinoma to Ferroptosis via Suppressing ACSL3 and GPX4., PMID:38003537
The BRD4-SRPK2-SRSF2 signal modulates the splicing efficiency of ACSL3 pre-mRNA and influences erastin-induced ferroptosis in osteosarcoma cells., PMID:37993451
Identification of Diagnosis and Typological Characteristics Associated with Ferroptosis for Ulcerative Colitis via Bioinformatics and Machine Learning., PMID:37957905
HSP70 via HIF-1 α SUMOylation inhibits ferroptosis inducing lung cancer recurrence after insufficient radiofrequency ablation., PMID:37948404
Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma., PMID:37920878
Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis., PMID:37903763
Maturation of lipid metabolism in the fetal and newborn sheep heart., PMID:37867472
Integrated analysis of transcriptomic and proteomic alterations in mouse models of ALS/FTD identify early metabolic adaptions with similarities to mitochondrial dysfunction disorders., PMID:37779364
Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress., PMID:37736299
Acyl-CoA synthetase expression in human skeletal muscle is reduced in obesity and insulin resistance., PMID:37726199
Construction and validation of a novel ferroptosis-related prognostic signature for lung adenocarcinoma., PMID:37691861
[Research advances on the role of ACSL3 in the atherosclerosis]., PMID:37583046
Identification of the novel markers of PPAR signalling affecting immune microenvironment and immunotherapy response of lung adenocarcinoma patients., PMID:37556076
Development of tryptophan metabolism patterns to predict prognosis and immunotherapeutic responses in hepatocellular carcinoma., PMID:37540213
Pan-cancer analysis identifies LPCATs family as a prognostic biomarker and validation of LPCAT4/WNT/β-catenin/c-JUN/ACSL3 in hepatocellular carcinoma., PMID:37294538
Mechanisms of ferroptosis with immune infiltration and inflammatory response in rotator cuff injury., PMID:37230182
Proteogenomic characterization of ferroptosis regulators reveals therapeutic potential in glioblastoma., PMID:37158834
Identification and validation of ferroptosis-related genes in lipopolysaccharide-induced acute lung injury., PMID:37149072
Identification of a m6A-related ferroptosis signature as a potential predictive biomarker for lung adenocarcinoma., PMID:37072786
Hepatic gene expression profiles during fed-fasted-refed state in mice., PMID:36936413
Ferroptosis-related ACSL3 and ACTC1 predict metastasis-free survival for prostate cancer patients undergoing radical radiotherapy., PMID:36577584
Effects of dehydroabietic acid on nontarget lipidomics and proteomics of HepG2., PMID:36532744
Prognostic Role of Long-Chain Acyl-Coenzyme A Synthetase Family Genes in Patients with Clear Cell Renal Cell Carcinoma: A Comprehensive Bioinformatics Analysis Confirmed with External Validation Cohorts., PMID:36529627
IGF2BP3 is an essential N6-methyladenosine biotarget for suppressing ferroptosis in lung adenocarcinoma cells., PMID:36457846
An autophagy-related gene prognostic index predicting biochemical recurrence, metastasis, and drug resistance for prostate cancer., PMID:36412461
For research use only. Not for human or drug use.
