Catalog No.
YHF85501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys90-Asn228
Predicted molecular weight
18.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01105
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein SET, Phosphatase 2A inhibitor I2PP2A, SET, HLA-DR-associated protein II, PHAPII, TAF-I, I-2PP2A, Inhibitor of granzyme A-activated DNase, IGAAD, Template-activating factor I
TTC36 promotes proliferation and drug resistance in hepatocellular carcinoma cells by inhibiting c-Myc degradation., PMID:40274799
Phosphorylation of cytochrome c at tyrosine 48 finely regulates its binding to the histone chaperone SET/TAF-Iβ in the nucleus., PMID:39548742
Chidamide maintenance therapy after allo-HSCT in SET-NUP214 fusion positive T-ALL patients: A report of two cases., PMID:39233093
Paradoxical action of PP2A inhibition and its potential for therapeutic sensitization., PMID:39150149
Merkel Cell Polyomavirus targets SET/PP2A complex to promote cellular proliferation and migration., PMID:38917692
Effects of Combination of Ethanol With Ritonavir, Lopinavir or Darunavir on Expression and Localization of the ER-Associated Set Protein and Infection of HIV-1 Pseudovirus in Primary Human Cells., PMID:38771756
USP7 interacts with and destabilizes oncoprotein SET., PMID:38555840
Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis., PMID:38355937
Structural analysis of polysaccharide from Inonotus obliquus and investigate combined impact on the sex hormones, intestinal microbiota and metabolism in SPF male mice., PMID:38331071
PP2A complex disruptor SET prompts widespread hypertranscription of growth-essential genes in the pancreatic cancer cells., PMID:38277454
PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells., PMID:38141761
SET protein as an epigenetics target., PMID:38131159
SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML., PMID:37891368
Set Protein Is Involved in FLT3 Membrane Trafficking., PMID:37190162
Circular MTHFD2L RNA-encoded CM-248aa inhibits gastric cancer progression by targeting the SET-PP2A interaction., PMID:37101395
Blast phase of chronic myeloid leukemia with concurrent BCR::ABL1 and SET::NUP214: A report of two cases., PMID:36321418
Spirulina platensis protein isolate nanoparticle stabilized O/W Pickering emulsions: Interfacial adsorption and bulk aggregation., PMID:36192888
CBX8 Together with SET Facilitates Ovarian Carcinoma Growth and Metastasis by Suppressing the Transcription of SUSD2., PMID:35894945
Structural Mechanism of TAF-Iβ Chaperone Function on Linker Histone H1.10., PMID:35870650
The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer., PMID:35843886
Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration., PMID:35713529
Improved Cell-Potent and Selective Peptidomimetic Inhibitors of Protein N-Terminal Methyltransferase 1., PMID:35209173
[Induction of hepatocellular carcinoma in B6C3 (F1) mice chronicly exposed to trichloroethylene with enhanced acetylation of histone H2AK9ac and SET expression in the liver tissue]., PMID:35164419
Role of SET oncoprotein in hepatocellular carcinoma: An immunohistochemical study., PMID:35156535
The protein level of the tumour-promoting factor SET is regulated by cell density., PMID:35076073
TRIM29 regulates the SETBP1/SET/PP2A axis via transcription factor VEZF1 to promote progression of ovarian cancer., PMID:34973391
HIF-Dependent NFATC1 Activation Upregulates ITGA5 and PLAUR in Intestinal Epithelium in Inflammatory Bowel Disease., PMID:34858489
MicroRNA-1915-3p inhibits cell migration and invasion by targeting SET in non-small-cell lung cancer., PMID:34774019
Microstructural Analysis of Whey/Soy Protein Isolate Mixed Gels Using Confocal Raman Microscopy., PMID:34574292
Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells., PMID:34489496
[Analysis of the clinical characteristics of 24 cases of hematological malignancies with SET-NUP214 fusion gene]., PMID:34384151
SET-NUP214 and MLL cooperatively regulate the promoter activity of the HoxA10 gene., PMID:34320268
1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1β/I2PP2A oncoprotein (residues 23-225)., PMID:34156643
The interaction of SET and protein phosphatase 2A as target for cancer therapy., PMID:34116173
Crosstalk between hnRNP K and SET in ATRA-induced differentiation in acute promyelocytic leukemia., PMID:34058077
Human TAF-Iα promotes oncogenic transformation via enhancement of cell proliferation and suppression of apoptosis., PMID:34021475
SET levels contribute to cohesion fatigue., PMID:33909454
SET Protein in Cancer: A Potential Therapeutic Target., PMID:33459234
Prognostic significance of SET-NUP214 fusion gene in acute leukemia after allogeneic hematopoietic stem cell transplantation., PMID:33327316
Embryonic Stem Cell Differentiation Is Regulated by SET through Interactions with p53 and β-Catenin., PMID:33296674
Higher content of microcystin-leucine-arginine promotes the survival of intrahepatic cholangiocarcinoma cells via regulating SET resulting in the poorer prognosis of patients., PMID:33241617
Protein phosphatase-1: dual activity regulation by Inhibitor-2., PMID:33125485
Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes., PMID:33043401
Cytotoxic potential of the Red Sea sponge Amphimedon sp. supported by in silico modelling and dereplication analysis., PMID:32975127
SET/TAF1 forms a distance-dependent feedback loop with Aurora B and Bub1 as a tension sensor at centromeres., PMID:32973131
New Cytotoxic Cerebrosides from the Red Sea Cucumber Holothuria spinifera Supported by In-Silico Studies., PMID:32752177
Synergic effect of OP449 and FTY720 on oral squamous cell carcinoma., PMID:32569675
Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer., PMID:32422974
New Cytotoxic Natural Products from the Red Sea Sponge Stylissa carteri., PMID:32375235
Anti-tumoral Effect of a Cell Penetrating and Interfering Peptide Targeting PP2A/SET Interaction., PMID:32337908
For research use only. Not for human or drug use.
