Catalog No.
YHK72701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu22-Glu97
Predicted molecular weight
22.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q93062
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hermes, Heart and RRM expressed sequence, RNA-binding protein with multiple splicing, HERMES, RBP-MS, RBPMS
Rag1-/- mice with T and B lymphocyte deficiency exhibit milder retinal inflammatory response and retinal ganglion cell injury after optic nerve crush., PMID:40312002
Targeted Neuroprotection of Retinal Ganglion Cells Via AAV2-hSyn-NGF Gene Therapy in Glaucoma Models., PMID:40244606
Correction for Du et al., The RNA-binding protein RBPMS inhibits smooth muscle cell-driven vascular remodeling in atherosclerosis and vascular injury., PMID:40203047
C/EBP Homologous Protein Expression in Retinal Ganglion Cells Induces Neurodegeneration in Mice., PMID:40076484
Loss of monocyte chemoattractant protein-1 reduced monocyte recruitment and preserved retinal ganglion cells in a mouse model of hypertensive glaucoma., PMID:40058724
RBPMS inhibits bladder cancer metastasis by downregulating MYC pathway through alternative splicing of ANKRD10., PMID:40044952
The RNA-binding protein RBPMS inhibits smooth muscle cell-driven vascular remodeling in atherosclerosis and vascular injury., PMID:39999164
Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease., PMID:39955563
HMGB2 knockdown ameliorates retinal ganglion cell injury by inhibiting NLRP3 inflammasome activation after retinal ischemia., PMID:39829613
Multiparametric grading of glaucoma severity by histopathology can enable post-mortem substratification of disease state., PMID:39762948
Precision medicine: an intrahepatic cholangiocarcinoma with a novel RBPMS-MET fusion sensitive to crizotinib., PMID:39658086
RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing., PMID:39574760
The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy., PMID:39565302
Intravitreal AAV2 gene delivery to feline retinal ganglion cells., PMID:39549467
Identification, expression, and function analysis of Rbpms2 splicing variants in Japanese flounder gonad., PMID:39414089
Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease., PMID:39345568
Crystallin β-b2 promotes retinal ganglion cell protection in experimental autoimmune uveoretinitis., PMID:39318470
RBPMS-AS1 sponges miR-19a-3p to restrain cervical cancer cells via enhancing PLCL1-mediated pyroptosis., PMID:39300709
FK962 protects retinal ganglion cell under hypoxia/reoxygenation: Possible involvement of glial cell line-derived neurotrophic factor signaling pathway., PMID:39284507
RNA binding protein with multiple splicing (RBPMS) promotes contractile phenotype splicing in human embryonic stem cell-derived vascular smooth muscle cells., PMID:39248180
Lycium barbarum glycopeptide promotes neuroprotection in ET-1 mediated retinal ganglion cell degeneration., PMID:39103918
Neuritin 1 Drives Therapeutic Preservation of Retinal Ganglion Cells in an Ex Vivo Human Glaucoma Model., PMID:38995841
Retinal Ganglion Cell Content Underlying Standard Automated Perimetry Size I to V Visual Sensitivities in the Non-Human Primate Experimental Glaucoma Model., PMID:38995114
The ketogenic diet and hypoxia promote mitophagy in the context of glaucoma., PMID:38841201
lncRNA Biomarkers of Glioblastoma Multiforme., PMID:38790894
POU6F2, a risk factor for glaucoma, myopia and dyslexia, labels specific populations of retinal ganglion cells., PMID:38698014
Interleukin-4 protects retinal ganglion cells and promotes axon regeneration., PMID:38650003
Comparison of Brn3a and RBPMS Labeling to Assess Retinal Ganglion Cell Loss During Aging and in a Model of Optic Neuropathy., PMID:38587440
Optimizing retinal ganglion cell nuclear staining for automated cell counting., PMID:38554800
RNA-Binding Proteins in Cardiomyopathies., PMID:38535111
Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland., PMID:38329731
Transsynaptic Degeneration of Retinal Ganglion Cells Following Lesions to Primary Visual Cortex in Marmosets., PMID:38306108
Induced Attenuation of Scleral TGF-β Signaling in Mutant Mice Increases Susceptibility to IOP-Induced Optic Nerve Damage., PMID:38294803
SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation., PMID:38195842
Protective effect of the natural flavonoid naringenin in mouse models of retinal injury., PMID:38052414
Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis., PMID:37943661
RBPMS regulates cardiomyocyte contraction and cardiac function through RNA alternative splicing., PMID:37890031
The RBPMSCreERT2-tdTomato mouse line for studying retinal and vascular relevant diseases., PMID:37867934
Identification of dual STRN-NTRK2 rearrangements in a high grade sarcoma, with good clinical response to first-line larotrectinib therapy., PMID:37865792
Tafluprost promotes axon regeneration after optic nerve crush via Zn2+-mTOR pathway., PMID:37832634
Myeloid/lymphoid neoplasm with a novel cryptic RBPMS::FGFR1 rearrangement presenting as de novo acute leukemias., PMID:37791611
HSP27 induced glaucomatous damage in mice of young and advanced age., PMID:37744880
Inducible Rbpms-CreERT2 Mouse Line for Studying Gene Function in Retinal Ganglion Cell Physiology and Disease., PMID:37566030
Cell-type specific regulator RBPMS switches alternative splicing via higher-order oligomerization and heterotypic interactions with other splicing regulators., PMID:37548402
Distribution and synaptic organization of substance P-like immunoreactive neurons in the mouse retina., PMID:37481742
Transcriptomic profiling of retinal cells reveals a subpopulation of microglia/macrophages expressing Rbpms marker of retinal ganglion cells (RGCs) that confound identification of RGCs., PMID:37121423
Assessment of the uniform field electroretinogram for mouse retinal ganglion cell functional analysis., PMID:37106219
Splicing factors in the heart: Uncovering shared and unique targets., PMID:37059416
In silico analysis of differentially expressed-aberrantly methylated genes in breast cancer for prognostic and therapeutic targets., PMID:37029310
mRNA translational specialization by RBPMS presets the competence for cardiac commitment in hESCs., PMID:36989351
For research use only. Not for human or drug use.
