Catalog No.
YHD01601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn26-Arg272
Predicted molecular weight
30.09 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13807
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Glycogen [starch] synthase, muscle, GYS1, GYS
Expanding the clinical phenotype and understanding the biochemical consequences of Muscle Glycogen Synthase Deficiency (GSD0B)., PMID:40398079
Identification of a Biomarker Panel in Extracellular Vesicles Derived From Non-Small Cell Lung Cancer (NSCLC) Through Proteomic Analysis and Machine Learning., PMID:40366616
FMO2+ cancer-associated fibroblasts sensitize anti-PD-1 therapy in patients with hepatocellular carcinoma., PMID:40316306
The metabolic enzyme GYS1 condenses with NONO/p54nrb in the nucleus and spatiotemporally regulates glycogenesis and myogenic differentiation., PMID:40200092
LC-HRMS profiling of Dendrobium huoshanense aqueous extract and its therapeutic effects on nonalcoholic fatty liver disease in mice through the TLR2-NF-κB and AMPK-SREBP1-SIRT1 signaling pathways., PMID:40107184
The inhibition of placental mTOR signaling leads to fetal growth restriction with abnormal glucose metabolism in different anatomical regions of placentas., PMID:40090159
Unveiling the crucial role of glycosylation modification in lung adenocarcinoma metastasis through artificial neural network-based spatial multi-omics single-cell analysis and Mendelian randomization., PMID:39948531
Glycogen synthase GYS1 overactivation contributes to glycogen insolubility and malto-oligoglucan-associated neurodegenerative disease., PMID:39806098
Identifying disulfidptosis-related biomarkers in epilepsy based on integrated bioinformatics and experimental analyses., PMID:39805370
The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome., PMID:39790063
A novel CD71 Centyrin:Gys1 siRNA conjugate reduces glycogen synthesis and glycogen levels in a mouse model of Pompe disease., PMID:39604266
Metformin Improves the Function of Abdominal Aortic Aneurysm Patient-Derived Aortic Smooth Muscle Cells., PMID:39321955
Overexpression of SLC2A1, ALDOC, and PFKFB4 in the glycolysis pathway drives strong drug resistance in 3D HeLa tumor cell spheroids., PMID:39295558
Insight in the (Phospho)proteome of Vascular Smooth Muscle Cells Derived From Patients With Abdominal Aortic Aneurysm Reveals Novel Disease Mechanisms., PMID:39206541
Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease., PMID:39171753
Unraveling pathogenesis, biomarkers and potential therapeutic agents for endometriosis associated with disulfidptosis based on bioinformatics analysis, machine learning and experiment validation., PMID:39061076
Disulfidptosis: A Novel Prognostic Criterion and Potential Treatment Strategy for Diffuse Large B-Cell Lymphoma (DLBCL)., PMID:39000261
PCK1-mediated glycogenolysis facilitates ROS clearance and chemotherapy resistance in cervical cancer stem cells., PMID:38871968
NMT2 alleviates depression-like behavior in a rat model of chronic unpredictable stress: An integrated proteomic and phosphoproteomic analysis., PMID:38852542
Glycogen synthesis is required for adaptive thermogenesis in beige adipose tissue and affects diet-induced obesity., PMID:38568151
Novel 4th-generation phytase improves broiler growth performance and reduces woody breast severity through modulation of muscle glucose uptake and metabolism., PMID:38559573
[Preliminary study on the effect of Echinococcus multilocaris on phenotypic transformations of glucose metabolism and polarization types in macrophages]., PMID:38413020
Downregulation of SLC3A2 mediates immune evasion and accelerates metastasis in oral squamous cell carcinoma., PMID:37927242
Inhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer., PMID:37816729
Gys1 Antisense Therapy Prevents Disease-Driving Aggregates and Epileptiform Discharges in a Lafora Disease Mouse Model., PMID:37700152
Molecular insights into the lipid-carbohydrates metabolism switch under the endurance effort in Arabian horses., PMID:37565649
MK8617 inhibits M1 macrophage polarization and inflammation via the HIF-1α/GYS1/UDPG/P2Y14 pathway., PMID:37404479
Glycogen-fuelled metabolism supports rapid mucosal-associated invariant T cell responses., PMID:37307453
Metabolic Cardiomyopathies and Cardiac Defects in Inherited Disorders of Carbohydrate Metabolism: A Systematic Review., PMID:37239976
Distribution of Exonic Variants in Glycogen Synthesis and Catabolism Genes in Late Onset Pompe Disease (LOPD)., PMID:37185710
Integrative metabolomic and transcriptomic analysis reveals difference in glucose and lipid metabolism in the longissimus muscle of Luchuan and Duroc pigs., PMID:37091786
Identification of novel immune subtypes and potential hub genes of patients with psoriasis., PMID:36890558
Lysosomal glycogen accumulation in Pompe disease results in disturbed cytoplasmic glycogen metabolism., PMID:36111639
Increased glucose influx and glycogenesis in lung cancer cells surviving after irradiation., PMID:35976051
Plasma Exosomal miRNAs Associated With Metabolism as Early Predictor of Gestational Diabetes Mellitus., PMID:35926094
The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex., PMID:35793618
Comparison of porcine milk microRNA expression in milk exosomes versus whole swine milk and prediction of target genes., PMID:35136833
DNA demethylase ALKBH1 promotes adipogenic differentiation via regulation of HIF-1 signaling., PMID:34922943
p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1., PMID:34758018
miR-140-5p Aggravates Insulin Resistance via Directly Targeting GYS1 and PPP1CC in Insulin-Resistant HepG2 Cells., PMID:34113143
Targeting Gys1 with AAV-SaCas9 Decreases Pathogenic Polyglucosan Bodies and Neuroinflammation in Adult Polyglucosan Body and Lafora Disease Mouse Models., PMID:33830476
Quantitative Proteomics Analysis for the Identification of Differential Protein Expression in Calf Muscles between Young and Old SD Rats Using Mass Spectrometry., PMID:33778255
The multi-target small-molecule inhibitor SB747651A shows in vitro and in vivo anticancer efficacy in glioblastomas., PMID:33727611
An inducible glycogen synthase-1 knockout halts but does not reverse Lafora disease progression in mice., PMID:33277363
Gut microbiota modulates expression of genes involved in the astrocyte-neuron lactate shuttle in the hippocampus., PMID:33191074
Chorionic somatomammotropin RNA interference alters fetal liver glucose utilization., PMID:33108344
Expression of Myosin Heavy Chain and Some Energy Metabolism-Related Genes in the Longissimus Dorsi Muscle of Krškopolje Pigs: Effect of the Production System., PMID:33062658
GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease., PMID:33034425
GYS1 induces glycogen accumulation and promotes tumor progression via the NF-κB pathway in Clear Cell Renal Carcinoma., PMID:32802186
For research use only. Not for human or drug use.
