Catalog No.
YHC93601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys31-Lys196
Predicted molecular weight
21.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12319
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FcERI, IgE Fc receptor subunit alpha, FCER1A, Fc-epsilon RI-alpha, FCE1A, High affinity immunoglobulin epsilon receptor subunit alpha
Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables., PMID:40189906
RNAseq of peripheral blood mononucleated cells exposed to platelet-rich fibrin and enamel matrix derivatives., PMID:39881164
Elevated MS4A2 and IgE interaction in nasal polyps contributing to poor postoperative prognosis in patients with eosinophilic chronic rhinosinusitis., PMID:39828458
A methodology for gene level omics-WAS integration identifies genes influencing traits associated with cardiovascular risks: the Long Life Family Study., PMID:39276247
SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma., PMID:39125709
Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response., PMID:38722600
Analysis of the potential molecular mechanisms of asthma and gastroesophageal reflux disease., PMID:38517701
Multi-omics Integration Identifies Genes Influencing Traits Associated with Cardiovascular Risks: The Long Life Family Study., PMID:38496585
Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology., PMID:38201301
Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria., PMID:37690594
Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticaria., PMID:37430141
Integrative single-cell RNA sequencing and metabolomics decipher the imbalanced lipid-metabolism in maladaptive immune responses during sepsis., PMID:37180171
A Co-Expressed Natural Antisense RNA FCER1A-AS Controls IgE-Dependent Immunity by Promoting Expression of FcεRIα., PMID:37154775
Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype., PMID:37108192
Topical emollient prevents the development of atopic dermatitis and atopic march in mice., PMID:37029953
Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response., PMID:36725846
Effects of an IgE receptor polymorphism acting on immunity, susceptibility to infection, and reproduction in a wild rodent., PMID:36645701
Signals from the TAFA4-PTEN-PU.1 axis alleviate nasal allergy by modulating the expression of FcεRI in mast cells., PMID:36368013
Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease., PMID:36153599
FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis., PMID:36087468
Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission., PMID:35304158
Revealing potential diagnostic gene biomarkers of septic shock based on machine learning analysis., PMID:35045818
FcER1: A Novel Molecule Implicated in the Progression of Human Diabetic Kidney Disease., PMID:34925339
A novel detection method for cross-linking of IgE-receptors by autoantibodies in chronic spontaneous urticaria., PMID:34465532
Involvement of Activation of Mast Cells via IgE Signaling and Epithelial Cell-Derived Cytokines in the Pathogenesis of Pollen Food Allergy Syndrome in a Murine Model., PMID:34127520
Cataloguing experimentally confirmed 80.7 kb-long ACKR1 haplotypes from the 1000 Genomes Project database., PMID:34039276
A pilot study of differential gene expressions in patients with cough variant asthma and classic bronchial asthma., PMID:33878997
Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma., PMID:33784348
The JmjC-domain protein NO66/RIOX-1 affects the balance between proliferation and maturation in acute myeloid leukemia., PMID:33745927
Haemonchus contortus infection induces a variable immune response in resistant and susceptible Pelibuey sheep., PMID:33667946
The relationship between released soluble FceRI-alpha and its cell surface density on human basophils., PMID:33481953
Vitamin D3-Induced Promotor Dissociation of PU.1 and YY1 Results in FcεRI Reduction on Dendritic Cells in Atopic Dermatitis., PMID:33443066
Identification of pathogenic genes and transcription factors in respiratory syncytial virus., PMID:33419394
Receptor dynamics regulates actin polymerization state through phosphorylation of cofilin in mast cells., PMID:33218687
Inverse association of FCER1A allergy variant in monocytes and plasmacytoid dendritic cells., PMID:33160967
Prediction of prognostic signatures in triple-negative breast cancer based on the differential expression analysis via NanoString nCounter immune panel., PMID:33138797
Interaction between functional polymorphisms in FCER1A and TLR2 and the severity of atopic dermatitis., PMID:32883546
AGK2 ameliorates mast cell-mediated allergic airway inflammation and fibrosis by inhibiting FcεRI/TGF-β signaling pathway., PMID:32565308
The Response of Tissue Mast Cells to TLR3 Ligand Poly(I:C) Treatment., PMID:32185237
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis., PMID:32035984
Imaging FCS delineates subtle heterogeneity in plasma membranes of resting mast cells., PMID:31895009
Identification of increased expression of activating Fc receptors and novel findings regarding distinct IgE and IgM receptors in Kawasaki disease., PMID:31816620
[TanshinoneⅡA attenuates carotid artery atherosclerosis by deactivating mast cells in adventitia]., PMID:31434435
Characterization of human FcεRIα chain expression and gene copy number in humanized rat basophilic leukaemia (RBL) reporter cell lines., PMID:31430311
Selection and characterization of FcεRI phospho-ITAM specific antibodies., PMID:31311408
Dendritic Cell Activating Receptor 1 (DCAR1) Associates With FcεRIγ and Is Expressed by Myeloid Cell Subsets in the Rat., PMID:31134097
Role of the IgE variable heavy chain in FcεRIα and superantigen binding in allergy and immunotherapy., PMID:30995457
Genetic variation in FCER1A predicts peginterferon alfa-2a-induced hepatitis B surface antigen clearance in East Asian patients with chronic hepatitis B., PMID:30972912
The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses., PMID:30735559
Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases., PMID:30658649
For research use only. Not for human or drug use.
