Catalog No.
YHA42801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys372
Predicted molecular weight
43.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15143
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Actin-related protein 2/3 complex subunit 1B, p41-ARC, Arp2/3 complex 41 kDa subunit, ARC41, ARPC1B
Targeting ARPC1B Overcomes Immune Checkpoint Inhibitor Resistance in Glioblastoma by Reversing Protumorigenic Macrophage Polarization., PMID:39841088
High expression of ARPC1B promotes the proliferation and apoptosis of clear cell renal cell carcinoma cells, leading to a poor prognosis., PMID:39818256
Development and validation of a prognostic prediction model for endometrial cancer based on CD8+ T cell infiltration-related genes., PMID:39654198
CircZMYM2 plays a pivotal role in osteosarcoma by regulating the translation of NACA and ARPC1B., PMID:39624324
Molecular basis of platelet granule defects., PMID:39617187
Recurrent eosinophilia with a novel homozygous ARPC1B mutation., PMID:39609360
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Actin-related protein 2/3 complex subunit 1B promotes ovarian cancer progression by regulating the AKT/PI3K/mTOR signaling pathway., PMID:39360160
Aspartyl proteases target host actin nucleator complex protein to limit epithelial innate immunity., PMID:39349750
CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes., PMID:39009834
Exploring the mechanism of Huanglian ointment in alleviating wound healing after anal fistula surgery through metabolomics and proteomics., PMID:38699024
Pan-cancer identified ARPC1B as a promising target for tumor immunotherapy and prognostic biomarker, particularly in READ., PMID:38689995
Description of a Novel Pathogenic Variant in the ARPC1B and a Severe Allergy in Two Infants., PMID:38485907
Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells., PMID:38421875
Neutrophil motility is regulated by both cell intrinsic and endothelial cell ARPC1B., PMID:38224139
High expression of ARPC1B correlates with immune infiltration and poor outcomes in glioblastoma., PMID:38188361
ARPC1B is a novel prognostic biomarker for kidney renal clear cell carcinoma and correlates with immune infiltration., PMID:37795220
The overexpression of actin related protein 2/3 complex subunit 1B(ARPC1B) promotes the ovarian cancer progression via activation of the Wnt/β-catenin signaling pathway., PMID:37304283
Is Your Kid Actin Out? A Series of Six Patients With Inherited Actin-Related Protein 2/3 Complex Subunit 1B Deficiency and Review of the Literature., PMID:36708766
Deciphering actin remodelling in immune cells through the prism of actin-related inborn errors of immunity., PMID:36525824
Actin related protein 2/3 complex subunit 1 up-regulation in the hypothalamus prevents high-fat diet induced obesity., PMID:36382618
ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells., PMID:36380368
Radiosensitivity in patients affected by ARPC1B deficiency: a new disease trait?, PMID:35967303
Hematopoietic Stem Cell Transplantation in ARPC1B Deficiency., PMID:35767111
Differential expression and analysis of extrachromosomal circular DNAs as serum biomarkers in lung adenocarcinoma., PMID:35441736
Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin., PMID:35317169
Comparative proteomics analysis of human stem cells from dental gingival and periodontal ligament., PMID:35297194
Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis., PMID:35222279
Identification of Tumor Antigens and Immune Subtypes of Glioblastoma for mRNA Vaccine Development., PMID:35185876
ARPC1B Is Associated with Lethal Prostate Cancer and Its Inhibition Decreases Cell Invasion and Migration In Vitro., PMID:35163398
Dual role of ARPC1B in regulating the network between tumor-associated macrophages and tumor cells in glioblastoma., PMID:35111386
Bioinformatics analysis of an animal model of diet-induced nonalcoholic fatty liver disease with rapid progression., PMID:34775841
ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells., PMID:34673575
[Study on the effect and mechanism of recombinant human intestinal trefoil factor on intestinal mucosal injury and repair in burned mice]., PMID:34645146
Identification of Tumor Antigens and Immune Landscape in Glioblastoma for mRNA Vaccine Development., PMID:34527020
Morphological profiling of human T and NK lymphocytes by high-content cell imaging., PMID:34233185
Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions., PMID:34135903
Molecular Mechanisms of Leukocyte Migration and Its Potential Targeting-Lessons Learned From MKL1/SRF-Related Primary Immunodeficiency Diseases., PMID:33692789
Case Report: A Novel Synonymous ARPC1B Gene Mutation Causes a Syndrome of Combined Immunodeficiency, Asthma, and Allergy With Significant Intrafamilial Clinical Heterogeneity., PMID:33679784
DHX36, BAX, and ARPC1B May Be Critical for the Diagnosis and Treatment of Tuberculosis., PMID:32774561
A male infant with COVID-19 in the context of ARPC1B deficiency., PMID:32683750
Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms., PMID:32661131
Whole-genome sequencing of patients with rare diseases in a national health system., PMID:32581362
Whole-genome sequencing of a sporadic primary immunodeficiency cohort., PMID:32499645
Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b., PMID:31977009
Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity., PMID:31710310
Flow Cytometric Determination of Actin Polymerization in Peripheral Blood Leukocytes Effectively Discriminate Patients With Homozygous Mutation in ARPC1B From Asymptomatic Carriers and Normal Controls., PMID:31379835
Cortical branched actin determines cell cycle progression., PMID:30971746
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency., PMID:30771411
An expanding network of cytoskeletal defects., PMID:30498066
For research use only. Not for human or drug use.
