Catalog No.
YHH82501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr650-Glu772
Predicted molecular weight
16.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q4VCS5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Angiomotin, KIAA1071, AMOT
Atypical Hippo signaling network: uncovering novel insights into head and neck cancer biology and advancements in precision intervention., PMID:40486910
Determining the minimal amount of DMSO necessary to stabilize the Angiomotin lipid binding domain., PMID:39866826
Live-cell FRET assay on the stoichiometry and affinity of the YAP complexes in MCF-7 cells., PMID:39818347
PSAT1 promotes the progression of colorectal cancer by regulating Hippo-YAP/TAZ-ID1 axis via AMOT., PMID:39739271
Function of orexin-1 receptor signaling in the olfactory tubercle in odor-guided attraction and aversion., PMID:39725686
Synaptic plasticity and roles of orexin in distinct domains of the olfactory tubercle., PMID:39574931
The ketogenic diet modulates tumor-associated neutrophil polarization via the AMOT-YAP/TAZ axis to inhibit colorectal cancer progression., PMID:39510146
The L27 domain of MPP7 enhances TAZ-YY1 cooperation to renew muscle stem cells., PMID:39496834
Blastocoel expansion and AMOT degradation cooperatively promote YAP nuclear localization during epiblast formation., PMID:39486633
Angiomotin cleavage promotes leader formation and collective cell migration., PMID:39389053
Cell size regulates human endoderm specification through actomyosin-dependent AMOT-YAP signaling., PMID:39094563
Induced expression of AMOT reverses adriamycin resistance in breast cancer cells., PMID:39021301
Rapamycin promotes the intestinal barrier repair in ulcerative colitis via the mTOR/PBLD/AMOT signaling pathway., PMID:38862095
Regulation of YAP and Wnt signaling by the endosomal protein MAMDC4., PMID:38787854
Association of low angiomotin-p130 and high YAP1 nuclear expression with adverse prognosis in epithelial ovarian cancer., PMID:38785315
Exposure to microcystin-LR promotes astrocyte proliferation both in vitro and in vivo via Hippo signaling pathway., PMID:38772146
Role of angiomotin family members in human diseases (Review)., PMID:38766307
Angiomotin family proteins in the Hippo signaling pathway., PMID:38760875
Genome-Wide CRISPR Screen Identifies an NF2-Adherens Junction Mechanistic Dependency for Cardiac Lineage., PMID:38752370
The cellular localization and oncogenic or tumor suppressive effects of angiomiotin-like protein 2 in tumor and normal cells., PMID:38717123
SOX4 regulates proliferation and apoptosis of human ovarian granulosa-like tumor cell line KGN through the Hippo pathway., PMID:38447391
circ-Amotl1 in extracellular vesicles derived from ADSCs improves wound healing by upregulating SPARC translation., PMID:38318480
The L27 Domain of MPP7 enhances TAZ-YY1 Cooperation to Renew Muscle Stem Cells., PMID:38077061
Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in Oral Cancer Cells., PMID:38067138
Function and regulation of miR-186-5p, miR-125b-5p and miR-1260a in chordoma., PMID:38012562
The L27 Domain of MPP7 enhances TAZ-YY1 Cooperation to Renew Muscle Stem Cells., PMID:37961392
Factor-inhibiting HIF (FIH) promotes lung cancer progression., PMID:37707961
Investigating whether exosomal miR-205-5p derived from tongue squamous cell carcinoma cells stimulates the angiogenic activity of HUVECs by targeting AMOT., PMID:37545216
WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT., PMID:37528078
Proteolytic activation of angiomotin by DDI2 promotes angiogenesis., PMID:37350545
Breast Cancer Therapeutics and Hippo Signaling Pathway: Novel MicroRNA-Gene-Protein Interaction Networks., PMID:37311160
The nuclear lamina couples mechanical forces to cell fate in the preimplantation embryo via actin organization., PMID:37248263
The role of Motin family proteins in tumorigenesis-an update., PMID:36973516
Suppression of YAP safeguards human naïve pluripotency., PMID:36398796
Multiphase coalescence mediates Hippo pathway activation., PMID:36318920
Fluid shear stress promotes periodontal ligament cells proliferation via p38-AMOT-YAP., PMID:36244032
p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin., PMID:36180740
Estrogen Regulates the Expression and Localization of YAP in the Uterus of Mice., PMID:36077170
Repression of linc01555 up-regulates angiomotin-p130 via the microRNA-122-5p/clic1 axis to impact vasculogenic mimicry-mediated chemotherapy resistance in small cell lung cancer., PMID:36045598
Increased SORBS3 expression in brain ageing contributes to autophagic decline via YAP1-WWTR1/TAZ signaling., PMID:35822241
Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling., PMID:35673984
Identification of Multiple Hub Genes in Acute Kidney Injury after Kidney Transplantation by Bioinformatics Analysis., PMID:35630098
WWOX-Mediated Degradation of AMOTp130 Negatively Affects Egress of Filovirus VP40 Virus-Like Particles., PMID:35107375
RICH1 inhibits breast cancer stem cell traits through activating kinases cascade of Hippo signaling by competing with Merlin for binding to Amot-p80., PMID:35064101
Fragment-based exploration of the 14-3-3/Amot-p130 interface., PMID:35036934
Yes-Associated Protein Is Required for ZO-1-Mediated Tight-Junction Integrity and Cell Migration in E-Cadherin-Restored AGS Gastric Cancer Cells., PMID:34572450
Comparison of a New 68Ga-Radiolabelled PET Imaging Agent sCD146 and RGD Peptide for In Vivo Evaluation of Angiogenesis in Mouse Model of Myocardial Infarction., PMID:34571954
Natural Membrane Differentiates Human Adipose-Derived Mesenchymal Stem Cells to Neurospheres by Mechanotransduction Related to YAP and AMOT Proteins., PMID:34564504
The Amot/integrin protein complex transmits mechanical forces required for vascular expansion., PMID:34433061
Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release., PMID:34284061
For research use only. Not for human or drug use.
