Catalog No.
YHD39401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg12-Gly176
Predicted molecular weight
21.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20340
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Rab-6A, Rab-6, RAB6A, RAB6
Systemic mechanism of Panax noteginseng saponins in antiaging based on network pharmacology combined with experimental validation., PMID:39691419
Rab6a enables BICD2/dynein-mediated trafficking of human papillomavirus from the trans-Golgi network during virus entry., PMID:39431827
The GTPase RAB6 is required for stem cell maintenance and cell migration in the gut epithelium., PMID:39431301
Proteomic biomarkers of long-term lung function decline in textile workers: a 35-year longitudinal study., PMID:39358504
The Rab6 post-Golgi secretory pathway contributes to herpes simplex virus 1 (HSV-1) egress., PMID:39136459
Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation., PMID:38830762
SNARE-ing the Reason for Post-Cardiac Surgery Critical Illness-Related Corticosteroid Insufficiency., PMID:38275610
Controlled Plasma Membrane Delivery of FGFR1 and Modulation of Signaling by a Novel Regulated Anterograde RTK Transport Pathway., PMID:38136383
Microtubule-dependent apical polarization of basement membrane matrix mRNAs in mouse epithelial cells., PMID:38103869
Exome sequencing to explore the possibility of predicting genetic susceptibility to the joint occurrence of polycystic ovary syndrome and Hashimoto's thyroiditis., PMID:37545519
EMT activates exocytotic Rabs to coordinate invasion and immunosuppression in lung cancer., PMID:37406091
RAB6A functions as a critical modulator of the stem-like subsets in cholangiocarcinoma., PMID:37278569
Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation., PMID:37172719
Conserved but not critical: Trafficking and function of NaV1.7 are independent of highly conserved polybasic motifs., PMID:37008789
Predicting Key Genes and Therapeutic Molecular Modelling to Explain the Association between Porphyromonas gingivalis (P. gingivalis) and Alzheimer's Disease (AD)., PMID:36982508
Rgp1 contributes to craniofacial cartilage development and Rab8a-mediated collagen II secretion., PMID:36843607
Involvement of Nrf2 in the immune regulation of Litopenaeus vannamei against Vibrio harveyi infection., PMID:36646337
The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation., PMID:36539035
RAB6 and dynein drive post-Golgi apical transport to prevent neuronal progenitor delamination., PMID:35979738
Caveolin-initiated macropinocytosis is required for efficient silica nanoparticles' transcytosis across the alveolar epithelial barrier., PMID:35676405
Depolarizing NaV and Hyperpolarizing KV Channels Are Co-Trafficked in Sensory Neurons., PMID:35589395
2D-GolgiTrack-a semi-automated tracking system to quantify morphological changes and dynamics of the Golgi apparatus and Golgi-derived membrane tubules., PMID:34783979
Generating Rab6 Conditional Knockout Mice., PMID:34453723
Autoantibody against the Rab6A/Rab6B in primary autoimmune cerebellar ataxia associated with Sjogren's syndrome: A case report., PMID:34332492
Legionella hijacks the host Golgi-to-ER retrograde pathway for the association of Legionella-containing vacuole with the ER., PMID:33760868
Rab6A as a Pan-Astrocytic Marker in Mouse and Human Brain, and Comparison with Other Glial Markers (GFAP, GS, Aldh1L1, SOX9)., PMID:33466322
Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure., PMID:33382739
Rab6 is required for rapid, cisternal-specific, intra-Golgi cargo transport., PMID:33024151
RAB6 GTPase regulates mammary secretory function by controlling the activation of STAT5., PMID:32895290
A rice small GTPase, Rab6a, is involved in the regulation of grain yield and iron nutrition in response to CO2 enrichment., PMID:32525991
Loss of Rab6a in the small intestine causes lipid accumulation and epithelial cell death from lactation., PMID:32496646
Low RAB6C expression is a predictor of tamoxifen benefit in estrogen receptor-positive/progesterone receptor-negative breast cancer., PMID:32257197
Vibrio parahaemolyticus Infection Influenced Trace Element Homeostasis, Impaired Antioxidant Function, and Induced Inflammation Response in Litopenaeus vannamei., PMID:32198646
Post-ER Stress Biogenesis of Golgi Is Governed by Giantin., PMID:31847122
Affinity-Based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors., PMID:31742988
Building sensory axons: Delivery and distribution of NaV1.7 channels and effects of inflammatory mediators., PMID:31681845
Epistatic Analysis of the Contribution of Rabs and Kifs to CATCHR Family Dependent Golgi Organization., PMID:31428608
A GFP-tagged version of the pseudorabies virus protein UL56 localizes to the Golgi and trans-Golgi network through a predicted C-terminal leucine-rich helix in transfected cells., PMID:31221185
Genome-Wide CRISPR Screen Reveals Autophagy Disruption as the Convergence Mechanism That Regulates the NRF2 Transcription Factor., PMID:31010806
A conserved retromer-independent function for RAB-6.2 in C. elegans epidermis integrity., PMID:30665892
Integrated phenotypic screening and activity-based protein profiling to reveal potential therapy targets of pancreatic cancer., PMID:30656306
Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells., PMID:30453527
Rab6A GTPase contributes to phenotypic modulation in pulmonary artery smooth muscle cells under hypoxia., PMID:30417421
Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation., PMID:30008265
The Biological Activity of AAV Vectors for Choroideremia Gene Therapy Can Be Measured by In Vitro Prenylation of RAB6A., PMID:29707603
Disease-associated mutations in human BICD2 hyperactivate motility of dynein-dynactin., PMID:28883039
Effects of organic acids and essential oils blend on growth, gut microbiota, immune response and disease resistance of Pacific white shrimp (Litopenaeus vannamei) against Vibrio parahaemolyticus., PMID:28882791
Prediction of adjuvant chemotherapy response in triple negative breast cancer with discovery and targeted proteomics., PMID:28594844
Involvement of ARHGEF10, GEF for RhoA, in Rab6/Rab8-mediating membrane traffic., PMID:28448737
The impact of erdosteine on cisplatin-induced ototoxicity: a proteomics approach., PMID:27878588