Catalog No.
YHG62301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gln165
Predicted molecular weight
20.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13636
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ras-related protein Rab-22B, Ras-related protein Rab-31, RAB22B, RAB31
RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners., PMID:40442479
EGFR/STAT3 signaling mediates the upregulation of CD47 in HPV-positive cervical cancer by activating p65 and exosome transporter RAB31., PMID:40353624
Construction and Validation of a T Cell Exhaustion-Related Prognostic Signature in Cholangiocarcinoma., PMID:40226355
Non-coding RNA RMRP governs RAB31-dependent MMP secretion, enhancing ovarian cancer invasion., PMID:40057205
Utilizing sc-linker to integrate single-cell RNA sequencing and human genetics to identify cell types and driver genes associated with non-small cell lung cancer., PMID:39849454
Deciphering the toxicity of polyhexamethylene guanidine phosphate in lung carcinogenesis: Mutational profiles and molecular mechanisms., PMID:39577803
XIAOPI formula inhibits chemoresistance and metastasis of triple-negative breast cancer by suppressing extracellular vesicle/CXCL1-induced TAM/PD-L1 signaling., PMID:39303510
RUNX1 isoforms regulate RUNX1 and target genes differentially in platelets-megakaryocytes: association with clinical cardiovascular events., PMID:39181539
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells., PMID:39051750
Lack of cellular prion protein causes Amyloid β accumulation, increased extracellular vesicle abundance, and changes to exosome biogenesis proteins., PMID:38970706
Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis., PMID:38941469
RAB31 drives extracellular vesicle fusion and cancer-associated fibroblast formation leading to oxaliplatin resistance in colorectal cancer., PMID:38939899
Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas., PMID:38347462
Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis., PMID:38289873
The m5 C methyltransferase NSUN2 promotes codon-dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer., PMID:37983928
RAB31 in glioma-derived endothelial cells promotes glioma cell invasion via extracellular vesicle-mediated enrichment of MYO1C., PMID:37953466
Bacillus anthracis spores are internalized in human lung epithelial cells by Rab GTPase-supported macropinocytosis., PMID:37586464
Overexpression of RAB31 in gastric cancer is associated with released exosomes and increased tumor cell invasion and metastasis., PMID:37222416
Umbilical cord DNA methylation is associated with body mass index trajectories from birth to adolescence., PMID:37088033
lncRNA MAGI2-AS3 suppresses castration-resistant prostate cancer proliferation and migration via the miR-106a-5p/RAB31 axis., PMID:36889366
Rab31 promotes metastasis and cisplatin resistance in stomach adenocarcinoma through Twist1-mediated EMT., PMID:36781842
Lysosome-related exosome secretion mediated by miR-26b / Rab31 pathway was associated with the proliferation and migration of MCF-7 cells treated with BPA., PMID:36701876
Association between Rab31/rs9965664 polymorphism and immunoglobulin therapy resistance in patients with Kawasaki disease., PMID:36329997
MiR-378a-3p acts as a tumor suppressor in gastric cancer via directly targeting RAB31 and inhibiting the Hedgehog pathway proteins GLI1/2., PMID:36245214
Transcriptome Changes in Glioma Cells Cultivated under Conditions of Neurosphere Formation., PMID:36231068
From Bowen disease to cutaneous squamous cell carcinoma: eight markers were verified from transcriptomic and proteomic analyses., PMID:36085041
A novel membrane targeting domain mediates the endosomal or Golgi localization specificity of small GTPases Rab22 and Rab31., PMID:35863437
Defective RAB31-mediated megakaryocytic early endosomal trafficking of VWF, EGFR, and M6PR in RUNX1 deficiency., PMID:35839075
Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation., PMID:35537882
LAMP2A regulates the loading of proteins into exosomes., PMID:35333565
LRG-1 promotes fat graft survival through the RAB31-mediated inhibition of hypoxia-induced apoptosis., PMID:35322540
Rab31, a receptor of advanced glycation end products (RAGE) interacting protein, inhibits AGE induced pancreatic β-cell apoptosis through the pAKT/BCL2 pathway., PMID:35314532
The Role of RAB GTPases and Its Potential in Predicting Immunotherapy Response and Prognosis in Colorectal Cancer., PMID:35154286
Rab31 promotes activation of hepatic stellate cells by accelerating TGF-β receptor II complex endocytosis., PMID:35091093
LncRNA HOXA10-AS Activated by E2F1 Facilitates Proliferation and Migration of Nasopharyngeal Carcinoma Cells Through Sponging miR-582-3p to Upregulate RAB31., PMID:35072529
Rab31 promotes the invasion and metastasis of cervical cancer cells by inhibiting MAPK6 degradation., PMID:34975321
Rab31-dependent regulation of transforming growth factor ß expression in breast cancer cells., PMID:34906074
Use of Immunohistochemistry to Determine Expression of Rab5 Subfamily of GTPases in Mature and Developmental Brains., PMID:34453724
Shigella escapes lysosomal degradation through inactivation of Rab31 by IpaH4.5., PMID:34296983
Analysis of mRNA‑lncRNA and mRNA‑lncRNA-pathway co‑expression networks based on WGCNA in developing pediatric sepsis., PMID:33949285
Transcriptional coregualtor NUPR1 maintains tamoxifen resistance in breast cancer cells., PMID:33542201
High expression of Rab31 confers a poor prognosis and enhances cell proliferation and invasion in oral squamous cell carcinoma., PMID:33469675
Identification of prognostic genes in uveal melanoma microenvironment., PMID:33196683
FGF2 Affects Parkinson's Disease-Associated Molecular Networks Through Exosomal Rab8b/Rab31., PMID:33101391
Increased RAB31 Expression in Cancer-Associated Fibroblasts Promotes Colon Cancer Progression Through HGF-MET Signaling., PMID:33072555
RAB31 is targeted by miR-26b and serves a role in the promotion of osteosarcoma., PMID:32973957
RAB31 marks and controls an ESCRT-independent exosome pathway., PMID:32958903
GANT61 plays antitumor effects by inducing oxidative stress through the miRNA-1286/RAB31 axis in osteosarcoma., PMID:32936498
Upregulation of Rab31 is associated with poor prognosis and promotes colorectal carcinoma proliferation via the mTOR/p70S6K/Cyclin D1 signalling pathway., PMID:32707053
Inverse control of Rab proteins by Yersinia ADP-ribosyltransferase and glycosyltransferase related to clostridial glucosylating toxins., PMID:32195351
For research use only. Not for human or drug use.
