Catalog No.
YHK70501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr157-Gly378
Predicted molecular weight
27.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H074
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PAIP1, PAIP-1, Polyadenylate-binding protein-interacting protein 1, PABP-interacting protein 1, Poly(A)-binding protein-interacting protein 1
PAIP1 binds to pre-mRNA and regulates alternative splicing of cancer pathway genes including VEGFA., PMID:39363305
Knockdown of PAIP1 Inhibits Breast Cancer Cell Proliferation by Regulating Cyclin E2 mRNA Stability., PMID:39259041
Qigui-Yishen decoction delays renal fibrosis in mice with chronic kidney disease by regulating TM and PAI-1., PMID:39006289
Prioritizing cervical cancer candidate genes using chaos game and fractal-based time series approach., PMID:38807013
YAP1-activated ZNF131 promotes hepatocellular carcinoma cell proliferation through transcriptional regulation of PAIP1., PMID:38341068
Pain/Stress, Mitochondrial Dysfunction, and Neurodevelopment in Preterm Infants., PMID:38286121
Intronless Pabpc6 encodes a testis-specific, cytoplasmic poly(A)-binding protein but is dispensable for spermatogenesis in the mouse†., PMID:38281153
Loss of Paip1 causes translation reduction and induces apoptotic cell death through ISR activation and Xrp1., PMID:37543696
Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence., PMID:37487098
PAIP1 regulates expression of immune and inflammatory response associated genes at transcript level in liver cancer cell., PMID:37101794
Human Proteome Microarray identifies autoantibodies to tumor-associated antigens as serological biomarkers for the diagnosis of hepatocellular carcinoma., PMID:36587394
PAIP1 is a novel oncogene in human hepatocellular carcinoma., PMID:36436074
Circ_0005576 Exerts an Oncogenic Role in Cervical Cancer via miR-1305-Dependent Regulation of PAIP1., PMID:35378711
Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome., PMID:35292784
Effect of PAIP1 on the metastatic potential and prognostic significance in oral squamous cell carcinoma., PMID:35153296
Upregulation of PAIP1 promotes the gallbladder tumorigenesis through regulating PLK1 level., PMID:34277791
The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation., PMID:33876849
High Paip1 Expression as a Potential Prognostic Marker in Hepatocellular Carcinoma., PMID:32871777
Effects of inducing apoptosis and inhibiting proliferation of siRNA on polyadenylate-binding protein-interacting protein 1 in tongue cell carcinoma., PMID:32827170
Paip1 overexpression is involved in the progression of gastric cancer and predicts shorter survival of diagnosed patients., PMID:31496746
Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis., PMID:31010277
Polyadenylate-binding protein-interacting proteins PAIP1 and PAIP2 affect translation termination., PMID:30992367
Role of Paip1 on angiogenesis and invasion in pancreatic cancer., PMID:30731074
Paip1 predicts poor prognosis and promotes tumor progression through AKT/GSK-3β pathway in lung adenocarcinoma., PMID:30496797
Murine PAIP1 stimulates translation of spermiogenic mRNAs stored by YBX2 via its interaction with YBX2†., PMID:30295753
Maternal whole blood cell miRNA-340 is elevated in gestational diabetes and inversely regulated by glucose and insulin., PMID:29358694
Paip1 affects breast cancer cell growth and represents a novel prognostic biomarker., PMID:29258905
Single-cell transcriptome sequencing reveals that cell division cycle 5-like protein is essential for porcine oocyte maturation., PMID:29222335
Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells., PMID:27454520
Biological insights into the expression of translation initiation factors from recombinant CHOK1SV cell lines and their relationship to enhanced productivity., PMID:26420881
The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding., PMID:26224628
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate., PMID:25721894
Paip1, an effective stimulator of translation initiation, is targeted by WWP2 for ubiquitination and degradation., PMID:25266661
Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase., PMID:24396066
Crystal structure of the middle domain of human poly(A)-binding protein-interacting protein 1., PMID:21539810
The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice., PMID:20739757
Herpes simplex virus proteins ICP27 and UL47 associate with polyadenylate-binding protein and control its subcellular distribution., PMID:19864386
Crystallization and preliminary X-ray diffraction analysis of the middle domain of Paip1., PMID:19851022
Analysis of mRNA associated factors during bovine oocyte maturation and early embryonic development., PMID:19697362
Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells., PMID:19020299
Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation., PMID:18725400
Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha., PMID:18559093
Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1., PMID:18397876
Rubella virus capsid protein interacts with poly(a)-binding protein and inhibits translation., PMID:18305028
Poly(A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly(A)-binding protein., PMID:17595167
Gene expression analysis of the murine model of amyotrophic lateral sclerosis: studies of the Leu126delTT mutation in SOD1., PMID:17583678
Regulation of poly(A)-binding protein through PABP-interacting proteins., PMID:17381337
Solution structure of the PABC domain from wheat poly (A)-binding protein: an insight into RNA metabolic and translational control in plants., PMID:17358048
[Translational control by the poly(A) binding protein: a check for mRNA integrity]., PMID:16913227
The stem-loop binding protein stimulates histone translation at an early step in the initiation pathway., PMID:15987814
For research use only. Not for human or drug use.
