Catalog No.
YHK70201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp31-Met315
Predicted molecular weight
33.61 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92597
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Differentiation-related gene 1 protein, CAP43, Reducing agents and tunicamycin-responsive protein, N-myc downstream-regulated gene 1 protein, Rit42, RTP, NDRG1, Protein NDRG1, DRG-1, Nickel-specific induction protein Cap43, DRG1
Unveiling the role of Ndrg1 gene on the oxidative stress induction behind the anticancer potential of styrylquinazoline derivatives., PMID:40341822
Insight into the Regulation of NDRG1 Expression., PMID:40332138
Mapping the Interactome of OSCC Prognostic-Associated Proteins NDRG1 and PGK1 Through Proximity Labeling Using TurboID., PMID:40304068
NDRG1/2 as a prognostic predictive biomarker of cervical cancer and its correlation with immune infiltration., PMID:40190258
Dicyclohexyl phthalate derails trophoblast function and lipid metabolism through NDRG1 by targeting PPARα:RXRα., PMID:40157530
Transforming Growth Factor Beta2 Promotes Migration and Inhibits the Proliferation of Gastric Cancer Cells by Regulating the pSmad2/3-NDRG1 Signaling Pathway., PMID:40151835
Hypoxia-induced NDRG1 C-terminal poly-phosphorylation impairs its tumor suppressor function in renal cell carcinoma., PMID:40139342
NDRG1 alleviates Erastin-induced ferroptosis of hepatocellular carcinoma., PMID:40119318
Lactate drives senescence-resistant lineages in hepatocellular carcinoma via histone H2B lactylation of NDRG1., PMID:39978571
SGK1 drives hippocampal demyelination and diabetes-associated cognitive dysfunction in mice., PMID:39962079
Identification and Functional Analysis of PANoptosis-Associated Genes in the Progression From Sepsis to ARDS., PMID:39854144
[NDRG1 protein expression in breast cancer samples, relationship with lymph nodes metastasis]., PMID:39686895
NDRG1 upregulation by ubiquitin proteasome system dysfunction aggravates neurodegeneration., PMID:39444004
NDRG1 Regulates Iron Metabolism and Inhibits Pathologic Cardiac Hypertrophy., PMID:39427843
Exploring epigenetic dynamics unveils a super-enhancer-mediated NDRG1-β-catenin axis in modulating gemcitabine resistance in pancreatic cancer., PMID:39366545
Circ_0015382 Regulates the miR-942-5p/NDRG1 Axis to Suppress Trophoblast Cell Functions., PMID:39354288
Mitochondrial ferritin upregulation by deferiprone reduced neuronal ferroptosis and improved neurological deficits via NDRG1/Yap pathway in a neonatal rat model of germinal matrix hemorrhage., PMID:39318194
Identification and Characterization of Novel Founder Mutations in NDRG1: Refining the Genetic Landscape of Charcot-Marie-Tooth Disease Type 4D in Bulgaria., PMID:39201732
NDRG1 enhances the sensitivity to Cetuximab by promoting Stat1 ubiquitylation in colorectal cancer., PMID:39128702
Elevated expression of N-myc downstream regulated gene 1 protein in glioblastomas reflects tumor angiogenesis and poor patient prognosis., PMID:39105501
NSUN6-mediated 5-methylcytosine modification of NDRG1 mRNA promotes radioresistance in cervical cancer., PMID:38970106
Merkel Cell Polyomavirus targets SET/PP2A complex to promote cellular proliferation and migration., PMID:38917692
SIRT6 Inhibits Anoikis of Colorectal Cancer Cells by Down-Regulating NDRG1., PMID:38891773
Multi-modal mechanisms of the metastasis suppressor, NDRG1: Inhibition of WNT/β-catenin signaling by stabilization of protein kinase Cα., PMID:38815861
CircSSBP2 acts as a MiR-2400 sponge to promote intramuscular preadipocyte proliferation by regulating NDRG1., PMID:38700639
Prostate cancer invasion is promoted by the miR-96-5p-induced NDRG1 deficiency through NF-κB regulation., PMID:38697817
N-myc downstream-regulated gene 1 can promote vasculogenic mimicry and angiogenesis in urothelial carcinoma., PMID:38561462
Overexpression of NDRG1 leads to poor prognosis in hepatocellular carcinoma through mediating immune infiltration and EMT., PMID:38290958
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer., PMID:38271137
NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1., PMID:38228036
LINC02561 promotes metastasis in HCC via HIF1-α/NDRG1/UPF1 axis., PMID:38013127
Association between NDRG1 protein expression and aggressive features of breast cancer: a systematic review and meta-analysis., PMID:37858101
Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation., PMID:37854018
Role of KLF4/NDRG1/DRP1 axis in hypoxia-induced pulmonary hypertension., PMID:37356737
mTOR Regulation of N-Myc Downstream Regulated 1 (NDRG1) Phosphorylation in Clear Cell Renal Cell Carcinoma., PMID:37298315
The Myc Family and the Metastasis Suppressor NDRG1: Targeting Key Molecular Interactions with Innovative Therapeutics., PMID:37280098
MAOA suppresses the growth of gastric cancer by interacting with NDRG1 and regulating the Warburg effect through the PI3K/AKT/mTOR pathway., PMID:37249744
NDRG1 facilitates self-renewal of liver cancer stem cells by preventing EpCAM ubiquitination., PMID:37165202
Diet-induced induction of hepatic serine/threonine kinase STK38 triggers proinflammation and hepatic lipid accumulation., PMID:37028764
ETS1 regulates NDRG1 to promote the proliferation, migration, and invasion of OSCC., PMID:36718855
TGFβ Governs the Pleiotropic Activity of NDRG1 in Triple-Negative Breast Cancer Progression., PMID:36594086
Neurodegenerative Disorder Risk in Krabbe Disease Carriers., PMID:36362324
Proteomic and Phosphoproteomic Analyses Reveal the Oncogenic Role of PTK7-NDRG1 Axis in Non-small-cell Lung Cancer Cell Resistance to AZD9291., PMID:36205702
MiR-96-5p induced NDRG1 deficiency promotes prostate cancer migration and invasion through regulating the NF-κB signaling pathway., PMID:35912726
Expression and clinicopathological significance of glucocorticoid receptor, SGK1, and NDRG1 in hormone-naïve prostate carcinoma., PMID:35861941
N-myc Downstream-Regulated Gene 1 (NDRG1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM)., PMID:35813230
HJURP regulates cell proliferation and chemo-resistance via YAP1/NDRG1 transcriptional axis in triple-negative breast cancer., PMID:35459269
NDRG1 is expressed in human granulosa cells: An implicative role of NDRG1 in the ovary., PMID:35386369
A splice altering variant in NDRG1 gene causes Charcot-Marie-Tooth disease, type 4D., PMID:35149926
N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling., PMID:35120575
For research use only. Not for human or drug use.
