Catalog No.
YHA77601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met86-Tyr309
Predicted molecular weight
26.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43766
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LS, LAS, Lipoic acid synthase, Lipoyl synthase, mitochondrial, Lipoate synthase, Lip-syn, LIAS
Cuproptosis-related gene signatures define the immune microenvironment in diabetic nephropathy., PMID:40460381
Clinically Relevant Cutoffs for Anti-Extractable Nuclear Antigen Line Immunoassays., PMID:40460086
[Effect and mechanism of Shenmai Injection in regulating copper death in myocardial fibrosis in rats]., PMID:40350947
Discovery of Cu(II)-Dipyridophenazine Complex for Synergistic Cuproptosis/Chemodynamic Therapy via Disrupting the Tricarboxylic Acid (TCA) Cycle in Metastatic TNBC., PMID:40348584
α-Synuclein targeted therapy with multiple pathological improvement for Parkinson's disease by macrocyclic amphiphile nanomedicine., PMID:40319681
Nanocatalytic system releases overloaded zinc ions and ROS to induce Znproptosis and interrupt cell cycle through inhibiting Akt/mTOR pathway., PMID:40225560
A novel anti-C6 based approach for IgG avidity testing in Lyme borreliosis: A proof-of-concept study., PMID:40188988
Identification of a Novel Antagonist of BRS-3 from Natural Products and Its Protective Effects Against H2O2-Induced Cardiomyocyte Injury., PMID:40141387
Knocking Down Ferredoxin 1 Inhibits the Progression of Colorectal Cancer and Regulates Cuproptosis via Mediating the Hippo Signaling Pathway., PMID:39987563
Evolocumab attenuates myocardial ischemia/reperfusion injury by blocking PCSK9/LIAS-mediated cuproptosis of cardiomyocytes., PMID:39930254
Peripheral mitochondrial transplantation alleviates diabetes-associated cognitive dysfunction by suppressing cuproptosis., PMID:39924054
Cuproptosis gene characterizes the immune microenvironment of diabetic nephropathy., PMID:39892769
Characterization of tumor prognosis and sensitive chemotherapy drugs based on cuproptosis-related gene signature in ovarian cancer., PMID:39849417
A comparative study evaluating three line immunoassays available for serodiagnosis of equine Lyme borreliosis: Detection of Borrelia burgdorferi sensu lato-specific antibodies in serum samples of vaccinated and non-vaccinated horses., PMID:39715214
Identification of cuproptosis-related genes in septic shock based on bioinformatic analysis., PMID:39652607
Immunogenicity Assessment of a 14-Valent Human Papillomavirus Vaccine Candidate in Mice., PMID:39591165
[The role of peritumoral electroacupuncture in regulating cuproptosis for sensitization of chemotherapy efficacy in mice with triple-negative breast cancer]., PMID:39557431
Engineered bacterial lipoate protein ligase A (lplA) restores lipoylation in cell models of lipoylation deficiency., PMID:39547509
LiaR-dependent gene expression contributes to antimicrobial responses in group A Streptococcus., PMID:39535201
Rhomboid-like 2 correlated with TME infiltration inhibits cuproptosis-related genes and drives malignant phenotype in clear cell renal cell carcinoma., PMID:39511359
Germline genetic variants in a case of familial cancer: RAD51D and four other co-segregated variants., PMID:39445568
Comprehensive analysis of the expression level, prognostic value, and immune infiltration of cuproptosis-related genes in human breast cancer., PMID:39432636
Identification of potential biomarkers of cuproptosis in cerebral ischemia., PMID:39360273
Bovine serum albumin-bound homologous targeted nanoparticles for breast cancer combinatorial therapy., PMID:39343270
Case report: Unveiling genetic and phenotypic variability in Nonketotic hyperglycinemia: an atypical early onset case associated with a novel GLRX5 variant., PMID:39323869
Acute inhibition of iron-sulfur cluster biosynthesis disrupts metabolic flexibility in mice., PMID:39229169
Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5., PMID:39223355
Triptolide-induced cuproptosis is a novel antitumor strategy for the treatment of cervical cancer., PMID:39198750
Risk factor prediction and immune correlation analysis of cuproptosis-related gene in osteoarthritis., PMID:39087591
Cuproptosis, the novel type of oxidation-induced cell death in thoracic cancers: can it enhance the success of immunotherapy?, PMID:39068453
Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype., PMID:39059380
Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies., PMID:39019011
FDX1 as a novel biomarker and treatment target for stomach adenocarcinoma., PMID:38983344
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex., PMID:38849365
Identification of 10 differentially expressed and cuproptosis-related genes in immune infiltration and prognosis of thyroid carcinoma., PMID:38650151
LiaR-dependent gene expression contributes to antimicrobial responses in group A Streptococcus., PMID:38617309
Bioinformatics-based dynamics of cuproptosis -related indicators in experimental silicosis., PMID:38564864
[Correlation of serum ferredoxin 1 and lipoic acid levels with severity of coronary artery disease]., PMID:38501416
Identification and validation of a novel cuproptosis signature for stratifying different prognostic, immune, metabolic, and therapeutic landscapes in pancreatic adenocarcinoma., PMID:38497885
CRYL1 is a Potential Prognostic Biomarker of Clear Cell Renal Cell Carcinoma Correlated with Immune Infiltration and Cuproptosis., PMID:38497139
Assessing the sensitivity and specificity of myositis-specific and associated autoantibodies: a sub-study from the MyoCite cohort., PMID:38479813
Association of Systemic Markers of Inflammation with Signs and Symptoms of Dry Eye Disease and Sjogren's Syndrome in the Dry Eye Assessment and Management (DREAM©) Study., PMID:38345056
Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens., PMID:38299155
Two-component system LiaSR negatively regulated the acid resistance and pathogenicity of Listeria monocytogenes 10403S., PMID:38225058
A novel cuproptosis-related prognostic gene signature in adrenocortical carcinoma., PMID:37997497
Identification of 6 cuproptosis-related genes for active ulcerative colitis with both diagnostic and therapeutic values., PMID:37904461
Exploring the role of LIAS-related cuproptosis in systemic lupus erythematosus., PMID:37903189
Comprehensive analysis of cuproptosis genes and cuproptosis-related genes as prognosis factors in esophageal squamous cell carcinoma., PMID:37866660
Bioinformatics analysis of copper death gene in diabetic immune infiltration., PMID:37773841
For research use only. Not for human or drug use.
