Catalog No.
YHK69501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys177-Ser410
Predicted molecular weight
29.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96GM5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
60 kDa BRG-1/Brm-associated factor subunit A, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, SWI/SNF complex 60 kDa subunit, BAF60A, SMARCD1, BRG1-associated factor 60A
SMARCD1 is a dual regulator of PD-L1 expression and cell proliferation facilitating tumor evasion., PMID:40228401
Identification of assembly mode of non-canonical BAF (ncBAF) chromatin remodeling complex core module., PMID:39732119
ARID1A is a coactivator of STAT5 that contributes to CD8+ T cell dysfunction and anti-PD-1 resistance in gastric cancer., PMID:39549895
iTreg cells-secreted IL10 alleviates lupus nephritis through inactivating lncRNA HAR1A transcription to suppress SMARCD1-mediated iNOS activation., PMID:39501640
Low SMARCD3 expression is associated with poor prognosis in patients with prostate cancer., PMID:39442954
SMARCD1 is an essential expression-restricted metastasis modifier., PMID:39390150
Smarcd1 subunit of SWI/SNF chromatin-remodeling complexes collaborates with E2a to promote murine lymphoid specification., PMID:39232562
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer., PMID:39029464
SMARCD1 is a "Goldilocks" metastasis modifier., PMID:38410477
Pan-cancer analyses of bromodomain containing 9 as a novel therapeutic target reveals its diagnostic, prognostic potential and biological mechanism in human tumours., PMID:38303608
De novo variants underlying monogenic syndromes with intellectual disability in a neurodevelopmental cohort from India., PMID:38114583
Tumor suppressive miR-99b-5p as an epigenomic regulator mediating mTOR/AR/SMARCD1 signaling axis in aggressive prostate cancer., PMID:38023145
Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis., PMID:37768825
Integrated analysis reveals SMARCD1 is a potential biomarker and therapeutic target in skin cutaneous melanoma., PMID:37401939
Genetic and genomic analyses of Drosophila melanogaster models of chromatin modification disorders., PMID:37036413
Zinc deficiency is associated with the development of ovarian endometrial cysts., PMID:37034203
The SMARCD Family of SWI/SNF Accessory Proteins Is Involved in the Transcriptional Regulation of Androgen Receptor-Driven Genes and Plays a Role in Various Essential Processes of Prostate Cancer., PMID:36611918
Transcription factor SS18L1 regulates the proliferation, migration and differentiation of Schwann cells in peripheral nerve injury., PMID:36046506
Long Noncoding RNA SBF2-AS1 Promotes Abdominal Aortic Aneurysm Formation through the miRNA-520f-3p/SMARCD1 Axis., PMID:35968497
BAF60a Deficiency in Macrophage Promotes Diet-Induced Obesity and Metabolic Inflammation., PMID:35822944
Assembly and interaction of core subunits of BAF complexes and crystal study of the SMARCC1/SMARCE1 binary complex., PMID:35158202
microRNA-99a-5p induces cellular senescence in gemcitabine-resistant bladder cancer by targeting SMARCD1., PMID:35148461
Smarcd1 antagonizes the apoptosis of injured MES23.5 DA cells by enhancing the effect of Six2 on GDNF expression., PMID:34233203
MUC1-C Activates the BAF (mSWI/SNF) Complex in Prostate Cancer Stem Cells., PMID:33323379
Smarcd1 Inhibits the Malignant Phenotypes of Human Glioblastoma Cells via Crosstalk with Notch1., PMID:33190170
The SWI/SNF subunit SMARCD3 regulates cell cycle progression and predicts survival outcome in ER+ breast cancer., PMID:33180234
NMR spectroscopy uncovers direct interaction between BAF60A and p53., PMID:33168186
BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation., PMID:32787523
Enhanced SMARCD1, a subunit of the SWI/SNF complex, promotes liver cancer growth through the mTOR pathway., PMID:32514535
BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning., PMID:32404872
hsa-miR-100-5p, an overexpressed miRNA in human ovarian endometriotic stromal cells, promotes invasion through attenuation of SMARCD1 expression., PMID:32299427
Dissecting the novel partners of nuclear c-Raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation., PMID:32283065
SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α., PMID:32029232
Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy., PMID:31992292
SMARCD1 is a transcriptional target of specific non-hotspot mutant p53 forms., PMID:31637714
High throughput circRNA sequencing analysis reveals novel insights into the mechanism of nitidine chloride against hepatocellular carcinoma., PMID:31506425
The ATPase BRG1/SMARCA4 is a protein interaction platform that recruits BAF subunits and the transcriptional repressor REST/NRSF in neural progenitor cells., PMID:31428904
Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues., PMID:31097748
A Syndromic Neurodevelopmental Disorder Caused by Mutations in SMARCD1, a Core SWI/SNF Subunit Needed for Context-Dependent Neuronal Gene Regulation in Flies., PMID:30879640
Epigenetic regulation of carnitine palmitoyltransferase 1 (Cpt1a) by high fat diet., PMID:30605728
BAF60A mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation., PMID:30515787
Immune Characteristics of Chinese Diffuse Large B-Cell Lymphoma Patients: Implications for Cancer Immunotherapies., PMID:29936139
SWI/SNF subunit expression heterogeneity in human aplastic anemia stem/progenitors., PMID:29596882
Ibuprofen reduces cell proliferation through inhibiting Wnt/β catenin signaling pathway in gastric cancer stem cells., PMID:29512256
Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle., PMID:29092888
miR-223 potentially targets SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinoma., PMID:29079174
Denervation-related alterations and biological activity of miRNAs contained in exosomes released by skeletal muscle fibers., PMID:29038428
Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations., PMID:28981154
Cellular senescence regulated by SWI/SNF complex subunits through p53/p21 and p16/pRB pathway., PMID:28716547
For research use only. Not for human or drug use.
