Catalog No.
YHK69101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Phe185
Predicted molecular weight
23.59 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y248
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GINS complex subunit 2, PSF2, DNA replication complex GINS protein PSF2, GINS2
A dynamic co-expression approach reveals Gins2 as a potential upstream modulator of HNSCC metastasis., PMID:39865116
Functional Analysis and Experimental Validation of the Prognostic and Immune Effects of the Oncogenic Protein CDC45 in Breast Cancer., PMID:39811603
The replicative helicase CMG is required for the divergence of cell fates during asymmetric cell division in vivo., PMID:39477966
Construction and Validation of a Mutation-Related Model in Papillary Renal Cell Carcinoma and Associated Immune Infiltration., PMID:38714185
GINS2 promotes the progression of human HNSCC by altering RRM2 expression., PMID:38517779
GINS2 regulates temozolomide chemosensitivity via the EGR1/ECT2 axis in gliomas., PMID:38467631
The integrative multi-omics approach identifies the novel competing endogenous RNA (ceRNA) network in colorectal cancer., PMID:37945594
Identification of potential biomarkers for melanoma cancer (black tumor) using bioinformatics strategy: a study based on GEO and SRA datasets., PMID:37875608
Estimating disease-free survival of thyroid cancer based on novel cuprotosis-related gene model., PMID:37745716
RNA Sequencing and Bioinformatics Analysis Reveals the Downregulation of DNA Replication Genes by Morindone in Colorectal Cancer Cells., PMID:37642925
In Silico Characterization of RNASEH2A Pathogenic Variants and Identification of Novel Splice Site Donor Variant c.549+1G>T in Indian Population., PMID:37456470
Exploring Key Genes with Diagnostic Value for Nonalcoholic Steatohepatitis Based on Bioinformatics Analysis., PMID:37323410
Exogenous hydrogen sulfide (H2S) exerts therapeutic potential in triple-negative breast cancer by affecting cell cycle and DNA replication pathway., PMID:37002576
Constructing and Analyzing Competing Endogenous RNA Networks Reveal Potential Biomarkers in Human Colorectal Cancer., PMID:36779495
Comprehensive Pan-Cancer Analysis of GINS2 for Human Tumour Prognosis and as an Immunological Biomarker., PMID:36466552
Breast Cancer Cells Reprogram the Oncogenic lncRNAs/mRNAs Coexpression Networks in Three-Dimensional Microenvironment., PMID:36359853
Gene interaction perturbation network deciphers a high-resolution taxonomy in colorectal cancer., PMID:36345721
GINS2 Is Downregulated in Peripheral Blood of Patients with Intervertebral Disk Degeneration and Promotes Proliferation and Migration of Nucleus Pulposus Cells., PMID:36092790
Combined analysis of expression, prognosis and immune infiltration of GINS family genes in human sarcoma., PMID:35896011
Identification of Hub Genes Associated With Non-alcoholic Steatohepatitis Using Integrated Bioinformatics Analysis., PMID:35559030
Identification of a 5-Nutrient Stress-Sensitive Gene Signature to Predict Survival for Colorectal Cancer., PMID:35496037
[Screening of differentially expressed genes for colorectal cancer and prediction of potential traditional Chinese medicine: based on bioinformatics]., PMID:35347966
GINS2 regulates the proliferation and apoptosis of colon cancer cells through PTP4A1., PMID:35137928
Novel Compound Heterozygous Variants in the CDC6 Gene in a Russian Patient with Meier-Gorlin Syndrome., PMID:35023948
Bioinformatics Analysis Explores Potential Hub Genes in Nonalcoholic Fatty Liver Disease., PMID:34777484
GINS Complex Subunit 2 Facilitates Gastric Adenocarcinoma Proliferation and Indicates Poor Prognosis., PMID:34629365
Biallelic GINS2 variant p.(Arg114Leu) causes Meier-Gorlin syndrome with craniosynostosis., PMID:34353863
MicroRNA miR-502-5p inhibits ovarian cancer genesis by downregulation of GINS complex subunit 2., PMID:34288816
Expression and prognosis analysis of GINS subunits in human breast cancer., PMID:33725952
GINS2 affects cell proliferation, apoptosis, migration and invasion in thyroid cancer via regulating MAPK signaling pathway., PMID:33537829
Identification of novel biomarkers and candidate small-molecule drugs in cutaneous melanoma by comprehensive gene microarrays analysis., PMID:33531976
Identification of Hub Genes as Potential Prognostic Biomarkers in Cervical Cancer Using Comprehensive Bioinformatics Analysis and Validation Studies., PMID:33447084
GINS2 attenuates the development of lung cancer by inhibiting the STAT signaling pathway., PMID:33391406
GINS2 was regulated by lncRNA XIST/miR-23a-3p to mediate proliferation and apoptosis in A375 cells., PMID:33389496
Screening and Discovery of New Potential Biomarkers and Small Molecule Drugs for Cervical Cancer: A Bioinformatics Analysis., PMID:33302814
Oleate acid-stimulated HMMR expression by CEBPα is associated with nonalcoholic steatohepatitis and hepatocellular carcinoma., PMID:33061798
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling., PMID:32747685
Identification of biomarkers in colon cancer based on bioinformatic analysis., PMID:35117850
Mining the prognostic significance of the GINS2 gene in human breast cancer using bioinformatics analysis., PMID:32724372
LncRNA SNHG3 promotes bladder cancer proliferation and metastasis through miR-515-5p/GINS2 axis., PMID:32596993
Tissue-Specific Requirement for the GINS Complex During Zebrafish Development., PMID:32548116
Knockdown of GINS2 inhibits proliferation and promotes apoptosis through the p53/GADD45A pathway in non-small-cell lung cancer., PMID:32181475
Prognostic values and prospective pathway signaling of MicroRNA-182 in ovarian cancer: a study based on gene expression omnibus (GEO) and bioinformatics analysis., PMID:31703725
GINS2 facilitates epithelial-to-mesenchymal transition in non-small-cell lung cancer through modulating PI3K/Akt and MEK/ERK signaling., PMID:31681988
Key genes associated with diabetes mellitus and hepatocellular carcinoma., PMID:31591054
Transcriptome sequencing profiles of cervical cancer tissues and SiHa cells., PMID:31456134
Analysis of functional hub genes identifies CDC45 as an oncogene in non-small cell lung cancer - a short report., PMID:30887286
Upregulation of DNA Metabolism-Related Genes Contributes to Radioresistance of Glioblastoma., PMID:30746964
Cancer Stem Cell based molecular predictors of tumor recurrence in Oral squamous cell carcinoma., PMID:30641296
GINS complex subunit 2 (GINS2) plays a protective role in alcohol-induced brain injury., PMID:30513217
For research use only. Not for human or drug use.
