Catalog No.
YHB53601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr2-Ser68
Predicted molecular weight
21.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95139
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NDUFB6, NADH-ubiquinone oxidoreductase B17 subunit, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6, Complex I-B17, CI-B17
Exploring the Mechanism of Kai-Xin-San to Improve Cognitive Deficits in AD Rats Induced by D-Gal and Aβ25-35 Based on Multi-Omics and Network Analysis., PMID:40033867
Identification and validation of cuproptosis-related genes in acetaminophen-induced liver injury using bioinformatics analysis and machine learning., PMID:38994365
Dysregulated immune and metabolic pathways are associated with poor survival in adult acute myeloid leukemia with CEBPA bZIP in-frame mutations., PMID:38253683
Multi-level profiling unravels mitochondrial dysfunction in myotonic dystrophy type 2., PMID:38240888
Identification of m7G regulator-mediated RNA methylation modification patterns and related immune microenvironment regulation characteristics in heart failure., PMID:36782329
Comparative transcriptomic analysis reveals region-specific expression patterns in different beef cuts., PMID:35596128
VDAC1 oligomerization may enhance DDP-induced hepatocyte apoptosis by exacerbating oxidative stress and mitochondrial DNA damage., PMID:34967508
Integrative Bioinformatics Analysis Revealed Mitochondrial Defects Underlying Hypoplastic Left Heart Syndrome., PMID:34934349
NDUFB6 Polymorphism Is Associated With Physical Activity-Mediated Metabolic Changes in Type 2 Diabetes., PMID:34659107
Steroid receptor RNA activator gene footprint in the progression and drug resistance of colorectal cancer through oxidative phosphorylation pathway., PMID:34520769
A study of Titanium and Magnesium particle-induced oxidative stress and toxicity to human osteoblasts., PMID:32919646
Hepatic HuR modulates lipid homeostasis in response to high-fat diet., PMID:32546794
Pathogenic variants in NUBPL result in failure to assemble the matrix arm of complex I and cause a complex leukoencephalopathy with thalamic involvement., PMID:31917109
Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice., PMID:31461471
Exome-Wide Rare Variant Analysis From the DiscovEHR Study Identifies Novel Candidate Predisposition Genes for Endometrial Cancer., PMID:31338326
Mutations in KARS cause a severe neurological and neurosensory disease with optic neuropathy., PMID:31116475
Preovulatory exposure to a protein-restricted diet disrupts amino acid kinetics and alters mitochondrial structure and function in the rat oocyte and is partially rescued by folic acid., PMID:30654812
Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons., PMID:30056117
Identification and functional annotation of metabolism-associated lncRNAs and their related protein-coding genes in gastric cancer., PMID:29992774
Subunit composition of respiratory chain complex 1 and its responses to oxygen in mitochondria from human donor livers., PMID:29096719
Gene Expression Profiling of H9c2 Cells Subjected to H2O2-Induced Apoptosis with/without AF-HF001., PMID:26607605
Downregulation of NDUFB6 due to 9p24.1-p13.3 loss is implicated in metastatic clear cell renal cell carcinoma., PMID:25315157
Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chain., PMID:23915000
Muscle inflammatory signaling in response to 9 days of physical inactivity in young men with low compared with normal birth weight., PMID:22968485
Exercise in type 2 diabetes: to resist or to endure?, PMID:22391950
YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation., PMID:22262461
A single nucleotide polymorphism associates with the response of muscle ATP synthesis to long-term exercise training in relatives of type 2 diabetic humans., PMID:22190678
Defective mitochondrial translation differently affects the live cell dynamics of complex I subunits., PMID:21978538
The NDUFB6 subunit of the mitochondrial respiratory chain complex I is required for electron transfer activity: a proof of principle study on stable and controlled RNA interference in human cell lines., PMID:21964293
Weight gain induced by an isocaloric pair-fed high fat diet: a nutriepigenetic study on FASN and NDUFB6 gene promoters., PMID:20729114
A high-sucrose isocaloric pair-fed model induces obesity and impairs NDUFB6 gene function in rat adipose tissue., PMID:20559011
Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes., PMID:19265027
Subunits of mitochondrial complex I exist as part of matrix- and membrane-associated subcomplexes in living cells., PMID:18826940
Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle., PMID:17948130
Clinical and genetic heterogeneity in chromosome 9p associated hereditary inclusion body myopathy: exclusion of GNE and three other candidate genes., PMID:12921793
Large-scale deletion and point mutations of the nuclear NDUFV1 and NDUFS1 genes in mitochondrial complex I deficiency., PMID:11349233
For research use only. Not for human or drug use.
