Catalog No.
YHF10801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg72-Glu356
Predicted molecular weight
35.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55209
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NAP-1-related protein, NRP, hNRP, Nucleosome assembly protein 1-like 1, NAP1L1
NAP1L1 degradation by FBXW7 reduces the deubiquitination of HDGF-p62 signaling to stimulate autophagy and induce primary cisplatin chemosensitivity in nasopharyngeal carcinoma., PMID:40414865
Somatic NAP1L1 p.D349E promotes cardiac hypertrophy through cGAS-STING-IFN signaling., PMID:40169585
The Altered Proteomic Landscape in Renal Tubular Epithelial Cells under High Oxalate Stimulation., PMID:39452123
NAP1L1 Promotes Endometrial Cancer Progression via EP300-Mediated DDX5 Promoter Acetylation., PMID:38953887
A novel IRF6 gene mutation impacting the regulation of TGFβ2-AS1 in the TGFβ pathway: A mechanism in the development of Van der Woude syndrome., PMID:38903762
CircDCAF8 promotes the progression of hepatocellular carcinoma through miR-217/NAP1L1 Axis, and induces angiogenesis and regorafenib resistance via exosome-mediated transfer., PMID:38816735
NAP1L1 regulates BIRC2 ubiquitination modification via E3 ubiquitin ligase UBR4 and hence determines hepatocellular carcinoma progression., PMID:38538582
Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia., PMID:38306602
Nucleosome assembly protein 1-like 1 (NAP1L1) in gastric cancer patients: a potential biomarker with diagnostic and prognostic utility., PMID:38258494
Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA charge mimicry to enhance chaperone efficiency., PMID:37790377
Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation., PMID:37593048
SP2-induced circPUM1 modulates chemoresistance and nature killer cell toxicity in oral squamous cell carcinoma., PMID:37556099
NAP1L1 is a novel microtubule-associated protein., PMID:37098731
Whole exome sequencing in unexplained recurrent miscarriage families identified novel pathogenic genetic causes of euploid miscarriage., PMID:36864708
Dynamic changes of 3'UTR length during oocyte-to-zygote transition of in vitro pig embryos., PMID:36755113
A New Role of NAP1L1 in Megakaryocytes and Human Platelets., PMID:36499021
Direct in situ protein tagging in Chlamydomonas reinhardtii utilizing TIM, a method for CRISPR/Cas9-based targeted insertional mutagenesis., PMID:36490276
NAP1L1 promotes the growth of colon cancer by activating HDGF/DDX5., PMID:36148951
Mechanism of client selection by the protein quality-control factor UBE2O., PMID:35915257
NAP1L1 Functions as a Novel Prognostic Biomarker Associated With Macrophages and Promotes Tumor Progression by Influencing the Wnt/β-Catenin Pathway in Hepatocellular Carcinoma., PMID:35664324
NAP1L1 promotes tumor proliferation through HDGF/C-JUN signaling in ovarian cancer., PMID:35351053
Alternative polyadenylation mechanism links secreted phosphoprotein 1 gene to glioblastoma., PMID:35275520
NAP1L1 promotes proliferation and chemoresistance in glioma by inducing CCND1/CDK4/CDK6 expression through its interaction with HDGF and activation of c-Jun., PMID:34959221
Trametes robiniophila represses angiogenesis and tumor growth of lung cancer via strengthening let-7d-5p and targeting NAP1L1., PMID:34898380
NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth., PMID:34774047
Disorder Genes Regulate the Progression of Ischemic Stroke through the NF-κB Signaling Pathway., PMID:34746300
Cytoplasmic NEAT1 Suppresses AML Stem Cell Self-Renewal and Leukemogenesis through Inactivation of Wnt Signaling., PMID:34609794
NAP1L1 targeting suppresses the proliferation of nasopharyngeal carcinoma., PMID:34563951
NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma., PMID:34368121
NAP1L1 and NAP1L4 Binding to Hypervariable Domain of Chikungunya Virus nsP3 Protein Is Bivalent and Requires Phosphorylation., PMID:34076483
Nucleosome assembly protein 1-like 1 (NAP1L1) in colon cancer patients: a potential biomarker with diagnostic and prognostic utility., PMID:33155206
NAP1L1: A Novel Human Colorectal Cancer Biomarker Derived From Animal Models of Apc Inactivation., PMID:32850460
Steviol, the active principle of the stevia sweetener, causes a reduction of the cells of the immunological system even consumed in low concentrations., PMID:32811239
Prognostic significance of NAP1L1 expression in patients with early lung adenocarcinoma., PMID:32522932
Anti-vimentin, anti-TUFM, anti-NAP1L1 and anti-DPYSL2 nanobodies display cytotoxic effect and reduce glioblastoma cell migration., PMID:32426045
Characterization of a nap1l1 transgenic reporter in zebrafish., PMID:31987905
Expression of nucleosome assembly protein 1 like genes in zebrafish embryos., PMID:31669493
Nucleosome assembly proteins NAP1L1 and NAP1L4 modulate p53 acetylation to regulate cell fate., PMID:31634504
NAP1L1 is a prognostic biomarker and contribute to doxorubicin chemotherapy resistance in human hepatocellular carcinoma., PMID:31516385
LncRNA CDKN2B-AS1 promotes tumor growth and metastasis of human hepatocellular carcinoma by targeting let-7c-5p/NAP1L1 axis., PMID:30165194
MiR-532-5p suppresses renal cancer cell proliferation by disrupting the ETS1-mediated positive feedback loop with the KRAS-NAP1L1/P-ERK axis., PMID:30082686
Multiple Host Factors Interact with the Hypervariable Domain of Chikungunya Virus nsP3 and Determine Viral Replication in Cell-Specific Mode., PMID:29899097
Network analysis of microRNAs, transcription factors, and target genes involved in axon regeneration., PMID:29616505
PRDM8 exhibits antitumor activities toward hepatocellular carcinoma by targeting NAP1L1., PMID:29572888
NAP1L1 Regulates Hepatitis C Virus Entry and Interacts with NS3., PMID:29541944
Nap1l1 Controls Embryonic Neural Progenitor Cell Proliferation and Differentiation in the Developing Brain., PMID:29490266
Histone octamer rearranges to adapt to DNA unwrapping., PMID:29323273
Biochemical and Biophysical Characterisation of Higher Oligomeric Structure of Rat Nucleosome Assembly Protein 1., PMID:29209909
NAP1L1 regulates NF-κB signaling pathway acting on anti-apoptotic Mcl-1 gene expression., PMID:28687276
Hepatitis C Virus NS5A Targets Nucleosome Assembly Protein NAP1L1 To Control the Innate Cellular Response., PMID:28659470