Catalog No.
YHK68501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp36-Gly172
Predicted molecular weight
17.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8WU39
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mesenteric estrogen-dependent adipose 7, Marginal zone B- and B1-cell-specific protein, Plasma cell-induced resident ER protein, PACAP, MZB1, Proapoptotic caspase adapter protein, Plasma cell-induced resident endoplasmic reticulum protein, pERp1, MEDA-7, MEDA7
ITIH4 attenuates acute lung injury by Fe-containing particulate matter in mice via Hippo pathway in type II alveolar epithelial cells., PMID:40437524
Proteomic Analysis of Transbronchial Biopsies to Discover Novel Biomarkers for Early Identification of Chronic Lung Allograft Dysfunction., PMID:40371053
Proteomic analysis reveals potential biomarker candidates in serous ovarian tumors - a preliminary study., PMID:40330446
Integrated metabolomics and transcriptomics to reveal the anti-tumor mechanisms of Sanghuangporus mongolicus ethyl acetate extract in H22 tumor-bearing mice., PMID:40210199
Ribosome profiling and single-cell RNA sequencing identify the unfolded protein response as a key regulator of pigeon lactation., PMID:39846187
Identification of core genes related to exosomes and screening of potential targets in periodontitis using transcriptome profiling at the single-cell level., PMID:39762852
Investigation into the molecular mechanisms of biomarkers in psoriasis vulgaris with reduced high-density lipoprotein levels based on bulk transcriptome sequencing data., PMID:39732346
Multi-omics analysis reveals interactions between host and microbes in Bama miniature pigs during weaning., PMID:39723142
Experimental and proteomics evidence revealed the protective mechanisms of Shemazhichuan Liquid in attenuating neutrophilic asthma., PMID:39515107
Unraveling potential gene biomarkers for dengue infection through RNA sequencing., PMID:39397194
Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587
Identification of Breast Cancer Subtypes Based on Endoplasmic Reticulum Stress-Related Genes and Analysis of Prognosis and Immune Microenvironment in Breast Cancer Patients., PMID:38725284
MZB1 regulates cellular proliferation, mitochondrial dysfunction, and inflammation and targets the PI3K-Akt signaling pathway in acute pancreatitis., PMID:38508349
Transcriptomic Analysis Reveals Sixteen Potential Genes Associated with the Successful Differentiation of Antibody-Secreting Cells through the Utilization of Unfolded Protein Response Mechanisms in Robust Responders to the Influenza Vaccine., PMID:38400120
Mzb1 Attenuates Atherosclerotic Plaque Vulnerability in ApoE-/- Mice by Alleviating Apoptosis and Modulating Mitochondrial Function., PMID:38294627
Differentially expressed miRNAs associated with generalized aggressive periodontitis., PMID:38123758
MZB1-mediated IgA secretion suppresses the development and progression of colorectal cancer triggered by gut inflammation., PMID:38101774
Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA., PMID:38094295
MZB1-expressing cells are essential for local immunoglobulin production in chronic rhinosinusitis with nasal polyps., PMID:37852603
Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26.ZEBOV/MVA-BN-Filo., PMID:37691146
Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus., PMID:37516862
Altered expression of MZB1 in periodontitis: A possible link to disease pathogenesis., PMID:37332260
An atlas of the bone marrow bone proteome in patients with dysproteinemias., PMID:37105956
Peripheral blood mononuclear cell derived biomarker detection using eXplainable Artificial Intelligence (XAI) provides better diagnosis of breast cancer., PMID:37030103
The human bone marrow plasma cell compartment in rheumatoid arthritis - Clonal relationships and anti-citrulline autoantibody producing cells., PMID:37001434
An atlas of the bone marrow bone proteome in patients with dysproteinemias., PMID:36747663
IL1RN and PRRX1 as a Prognostic Biomarker Correlated with Immune Infiltrates in Colorectal Cancer: Evidence from Bioinformatic Analysis., PMID:36483329
Circulatory cytokeratin 17, marginal zone B1 protein and leucine-rich α2-glycoprotein-1 as biomarkers for disease severity and fibrosis in systemic sclerosis patients., PMID:36277429
Single-cell transcriptome mapping identifies a local, innate B cell population driving chronic rejection after lung transplantation., PMID:36134664
MZB1 targeted by miR-185-5p inhibits the migration of human periodontal ligament cells through NF-κB signaling and promotes alveolar bone loss., PMID:35653494
Comprehensive Characterizations of Immune Receptor Repertoire in Tumors and Cancer Immunotherapy Studies., PMID:35605261
Comparison of immune cells and diagnostic markers between spondyloarthritis and rheumatoid arthritis by bioinformatics analysis., PMID:35509008
Proteomic profiling identifies novel diagnostic biomarkers and molecular subtypes for mucinous tubular and spindle cell carcinoma of the kidney., PMID:35043389
Identification of hub genes related to immune cell infiltration in periodontitis using integrated bioinformatic analysis., PMID:34993975
TNFSF13B and PPARGC1A expression is associated with tumor-infiltrating immune cell abundance and prognosis in clear cell renal cell carcinoma., PMID:34786042
Role of Polymeric Immunoglobulin Receptor in IgA and IgM Transcytosis., PMID:33668983
A proteomic approach towards understanding the pathogenesis of Mooren's ulcer., PMID:33647271
Single-cell RNA sequencing reveals cellular and molecular immune profile in a Pembrolizumab-responsive PD-L1-negative lung cancer patient., PMID:33506299
High-resolution Crystal Structure of Human pERp1, A Saposin-like Protein Involved in IgA, IgM and Integrin Maturation in the Endoplasmic Reticulum., PMID:33453188
MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells., PMID:33318509
MZB1 expression indicates poor prognosis in estrogen receptor-positive breast cancer., PMID:32963604
Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation., PMID:32759964
Proteomics and functional study reveal marginal zone B and B1 cell specific protein as a candidate marker of multiple myeloma., PMID:32377723
Salidroside suppresses nonsmall cell lung cancer cells proliferation and migration via microRNA-103-3p/Mzb1., PMID:32304408
Differential RNA splicing as a potentially important driver mechanism in multiple myeloma., PMID:32079689
COL1A1 and MZB1 as the hub genes influenced the proliferation, invasion, migration and apoptosis of rectum adenocarcinoma cells by weighted correlation network analysis., PMID:31901757
MZB1 folding and unfolding the role of IgA., PMID:31201222
MZB1 promotes the secretion of J-chain-containing dimeric IgA and is critical for the suppression of gut inflammation., PMID:31127044
Characterization of CNPY5 and its family members., PMID:31050855
Transcriptomic and proteomic analysis of iris tissue and aqueous humor in juvenile idiopathic arthritis-associated uveitis., PMID:30885419