Catalog No.
YHE04401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys305
Predicted molecular weight
37.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P33993
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DNA replication licensing factor MCM7, MCM2, P1.1-MCM3, CDC47 homolog, MCM7, CDC47
Biological characteristics of spontaneous ovarian cancer in Microtusfortis., PMID:40457786
Discovery and Mechanism of 16-19F, a Novel Synthetic Lethal Inhibitor of the PRMT5•MTA Complex in MTAP-Deleted Cancer Cells., PMID:40440106
USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination., PMID:40379725
[Corrigendum] MCM7 amplification and overexpression promote cell proliferation, colony formation and migration in esophageal squamous cell carcinoma by activating the AKT1/mTOR signaling pathway., PMID:40242967
Immunohistochemistry and machine learning study of DNA replication-associated proteins in uterine epithelial tumors and precursor lesions., PMID:40220589
Voluntary Exercise Attenuates Tumor Growth in a Preclinical Model of Castration-Resistant Prostate Cancer., PMID:40173332
Histone lactylation facilitates MCM7 expression to maintain stemness and radio-resistance in hepatocellular carcinoma., PMID:40118288
Transcriptomic Profiling Highlights Metabolic and Biosynthetic Pathways Involved in In Vitro Flowering in Anoectochilus roxburghii (Wall.) Lindl., PMID:40004461
The EZH2/MCM Complex/hTERT axis facilitates hepatocellular carcinoma progression by inhibiting cellular senescence., PMID:39933657
Expression of minichromosome maintenance proteins in the exfoliated cells supplement sputum cytology in the diagnosis of lung cancer., PMID:39927285
Functional Analysis and Experimental Validation of the Prognostic and Immune Effects of the Oncogenic Protein CDC45 in Breast Cancer., PMID:39811603
Reconstitution of human DNA licensing and the structural and functional analysis of key intermediates., PMID:39779677
Knockdown of ribosomal protein L22-like 1 arrests the cell cycle and promotes apoptosis in colorectal cancer., PMID:39737125
E2F8 facilitates malignant phenotypes of muscle-invasive bladder cancer via increasing MCM7 expression., PMID:39601318
Voluntary Exercise Attenuates Tumor Growth in a Preclinical Model of Castration-Resistant Prostate Cancer., PMID:39464116
SETD3-mediated histidine methylation of MCM7 regulates DNA replication by facilitating chromatin loading of MCM., PMID:39455502
Investigating the Mechanisms of Anti-tumoral Effect of Combination Therapy of Calcitriol and Sodium Pentaborate Pentahydrate on HepG2 Hepatocellular Carcinoma Cells., PMID:39441231
Beyond ribosomal function: RPS6 deficiency suppresses cholangiocarcinoma cell growth by disrupting alternative splicing., PMID:39309509
MCM proteins are up-regulated in placentas of women with reduced insulin sensitivity., PMID:39268985
Prognostic and Clinical Significance of the Proliferation Marker MCM7 in Breast Cancer., PMID:39191229
Analysis of different expression RNA binding protein genes in mouse microglia cell from the brains of mice 72 h after subarachnoid hemorrhage or sham operation., PMID:39095742
CMG helicase disassembly is essential and driven by two pathways in budding yeast., PMID:39039287
RNF8-mediated multi-ubiquitination of MCM7: Linking disassembly of the CMG helicase with DNA damage response in human cells., PMID:39004272
The shared mechanism and potential diagnostic markers for premature ovarian failure and dry eye disease., PMID:39003404
Biomarkers for prognosis of meningioma patients: A systematic review and meta-analysis., PMID:38758750
The splicing factor WBP11 mediates MCM7 intron retention to promote the malignant progression of ovarian cancer., PMID:38561505
Chalkiness and premature controlled by energy homeostasis in OsNAC02 Ko-mutant during vegetative endosperm development., PMID:38494545
Regulation of cancer stem cells by CXCL1, a chemokine whose secretion is controlled by MCM2., PMID:38454443
CUL4A Ubiquitin Ligase Is an Independent Predictor of Overall Survival in Pancreatic Adenocarcinoma., PMID:38423594
RNF125‑mediated ubiquitination of MCM6 regulates the proliferation of human liver hepatocellular carcinoma cells., PMID:38298426
Rare Deletions or Large Duplications Contribute to Genetic Variation in Patients with Severe Tinnitus and Meniere Disease., PMID:38254912
Decreased NSD2 impairs stromal cell proliferation in human endometrium via reprogramming H3K36me2., PMID:38236723
Heterogeneous Expression Patterns of the Minichromosome Maintenance Complex Members in Retinoblastoma Unveil Its Clinical Significance., PMID:38231525
WWOX promotes osteosarcoma development via upregulation of Myc., PMID:38182577
Retracted: High-Throughput Screening and Molecular Dynamics Simulation of Natural Products for the Identification of Anticancer Agents against MCM7 Protein., PMID:38152742
Phospholipase PLCE1 Promotes Transcription and Phosphorylation of MCM7 to Drive Tumor Progression in Esophageal Cancer., PMID:38117512
Effects of geniposide on innate immunity and antiviral activity of Scyllaparamamosain., PMID:38104694
Effects of environmental pollutant benzop[α]yrene on the innate immunity of Scylla paramamosain and its mechanism., PMID:37967729
Single-cell transcriptomics reveals subtype-specific molecular profiles in Nrf2-deficient macrophages from murine atherosclerotic aortas., PMID:37965327
HMGN2 and Histone H1.2: potential targets of a novel probiotic mixture for seasonal allergic rhinitis., PMID:37869664
Phylogeny and species delimitations in the economically, medically, and ecologically important genus Samsoniella (Cordycipitaceae, Hypocreales)., PMID:37828936
Hesperomyces (Fungi, Ascomycota) associated with Hyperaspis ladybirds (Coleoptera, Coccinellidae): Rethinking host specificity., PMID:37746211
The effect of reactive oxygen species (ROS) in immunity and WSSV infection of Scylla paramamosain., PMID:37730076
First Report of Peanut Black Pod Rot Caused by Berkeleyomyces rouxiae in China., PMID:37712823
New Resinogalea species from Araucaria araucana resin in Chile and reclassification of the genus in the Cryptocaliciomycetidae., PMID:37596646
Early diagnostic and prognostic biomarkers for gastric cancer: systems-level molecular basis of subsequent alterations in gastric mucosa from chronic atrophic gastritis to gastric cancer., PMID:37594635
DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans., PMID:37590372
TFRC-RNA interactions show the regulation of gene expression and alternative splicing associated with IgAN in human renal tubule mesangial cells., PMID:37547464
Hydroquinidine displays a significant anticarcinogenic activity in breast and ovarian cancer cells via inhibiting cell-cycle and stimulating apoptosis., PMID:37529110
Minichromosome maintenance proteins in lung adenocarcinoma: Clinical significance and therapeutic targets., PMID:37517032
For research use only. Not for human or drug use.
