Catalog No.
YHG82901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp23-Glu340
Predicted molecular weight
37.41 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14565
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Meiotic recombination protein DMC1/LIM15 homolog, LIM15, DMC1, DMC1H
A variant in RNF212B may contribute to female infertility and recurrent pregnancy loss., PMID:40259604
Structural basis for Rad54- and Hed1-mediated regulation of Rad51 during the transition from mitotic to meiotic recombination., PMID:40196570
ATP hydrolysis-driven structural transitions within the S. cerevisiae Rad51 and Dmc1 nucleoprotein filaments., PMID:40166259
The KMT2 complex protein ASH2L is required for meiotic prophase progression but dispensable for mitosis in differentiated spermatogonia., PMID:39992154
Dynamic changes in histone lysine lactylation during meiosis prophase I in mouse spermatogenesis., PMID:39928879
SDG8 and HUB2 depositing euchromatin histone marks play important roles in meiosis and crossing-over regulation., PMID:39916632
ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse., PMID:39589400
Hop2-Mnd1 functions as a DNA sequence fidelity switch in Dmc1-mediated DNA recombination., PMID:39463417
FIGL1 attenuates meiotic interhomolog repair and is counteracted by the RAD51 paralog XRCC2 and the chromosome axis protein ASY1 during meiosis., PMID:39420761
Low-temperature-induced disruption of reproductive axis and sperm vitality via stress axis in Monopterus albus., PMID:39368755
The role of RAD51 regulators and variants in primary ovarian insufficiency, endometriosis, and polycystic ovary syndrome., PMID:39359934
The Swi5-Sfr1 complex regulates Dmc1- and Rad51-driven DNA strand exchange proceeding through two distinct three-stranded intermediates by different mechanisms., PMID:39340300
BRCA2 stabilises RAD51 and DMC1 nucleoprotein filaments through a conserved interaction mode., PMID:39333100
Mei5-Sae3 stabilizes Dmc1 nucleating clusters for efficient Dmc1 assembly on RPA-coated single-stranded DNA., PMID:39275989
Role of sodium-dependent vitamin C transporter 2 in human periodontal ligament fibroblasts., PMID:39225294
[Lycium barbarum miR2911-loaded exosomes promote spermatogenic function recovery in rats with non-obstructive azoospermia by regulating Wnt/β-catenin signaling pathways]., PMID:39212356
Fance deficiency impaired DNA damage repair of prospermatogonia and altered the repair dynamics of spermatocytes., PMID:39210375
Identification and expression analysis of dmc1 in Chinese soft-shell turtle (Pelodiscus sinensis) during gametogenesis., PMID:39153704
FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading., PMID:39147779
DNA cytosine methyltransferases differentially regulate genome-wide hypermutation and interhomolog recombination in Trichoderma reesei meiosis., PMID:39021337
Arginine Promoted Ovarian Development in Pacific White Shrimp Litopenaeus vannamei via the NO-sGC-cGMP and TORC1 Signaling Pathways., PMID:38998098
Mutational analysis of Mei5, a subunit of Mei5-Sae3 complex, in Dmc1-mediated recombination during yeast meiosis., PMID:38924305
DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces., PMID:38828772
DNA-binding site II is required for RAD51 recombinogenic activity in Arabidopsis thaliana., PMID:38803223
BRCA1 safeguards genome integrity by activating chromosome asynapsis checkpoint to eliminate recombination-defective oocytes., PMID:38696471
Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis., PMID:38664461
The Dmc1 recombinase physically interacts with and promotes the meiotic crossover functions of the Mlh1-Mlh3 endonuclease., PMID:38657110
Antagonistic activity of Phaeobacter piscinae against the emerging fish pathogen Vibrio crassostreae in aquaculture feed algae., PMID:38349149
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging., PMID:38173016
Positive and negative regulators of RAD51/DMC1 in homologous recombination and DNA replication., PMID:38142595
Homologous Recombination and Repair Functions Required for Mutagenicity during Yeast Meiosis., PMID:38002960
Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice., PMID:37977820
FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination., PMID:37891173
BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination., PMID:37889963
SRSF1-mediated alternative splicing is required for spermatogenesis., PMID:37781512
SCFRMF mediates degradation of the meiosis-specific recombinase DMC1., PMID:37598222
Studying the effect of hyperoside on recovery from cyclophosphamide induced oligoasthenozoospermia., PMID:37578152
Recombinase-independent chromosomal rearrangements between dispersed inverted repeats in Saccharomyces cerevisiae meiosis., PMID:37548404
Three-color dSTORM Imaging and Analysis of Recombination Foci in Mouse Spread Meiotic Nuclei., PMID:37497444
In vivo versus in silico assessment of potentially pathogenic missense variants in human reproductive genes., PMID:37459509
The FLIP-FIGNL1 complex regulates the dissociation of RAD51/DMC1 in homologous recombination and replication fork restart., PMID:37439366
Hop2-Mnd1 and Swi5-Sfr1 stimulate Dmc1 filament assembly using distinct mechanisms., PMID:37395447
RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis., PMID:37378420
Episomal and chromosomal DNA replication and recombination in Entamoeba histolytica., PMID:37363402
FIGL1 coordinates with dosage-sensitive BRCA2 in modulating meiotic recombination in maize., PMID:37293848
The Msh5 complex shows homeostatic localization in response to DNA double-strand breaks in yeast meiosis., PMID:37274743
Differential expression of meiosis and homologous recombination-related genes in the life cycle of Trypanosoma cruzi., PMID:37272974
The role of conserved amino acid residues of Sae3 in Mei5-Sae3 complex for Dmc1 assembly in meiotic recombination., PMID:37225456
The Hop2-Mnd1 Complex and Its Regulation of Homologous Recombination., PMID:37189409
Maternal exposure to dibutyl phthalate regulates MSH6 crotonylation to impair homologous recombination in fetal oocytes., PMID:37167869
For research use only. Not for human or drug use.
