Catalog No.
YHK68301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp63-Ser268
Predicted molecular weight
24.89 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UHI6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DP103, Gemin-3, DDX20, Probable ATP-dependent RNA helicase DDX20, Component of gems 3, DEAD box protein DP 103, DEAD box protein 20, GEMIN3
A critical genetic interaction between Gemin3/Ddx20 and translation initiation factor NAT1/eIF4G2 drives development., PMID:39924071
DAPK enhances DDX20 protein stability via suppression of TRIM25-mediated ubiquitination-based DDX20 degradation., PMID:39558224
A translation regulator that drives spermatogonial stem cell formation., PMID:39382845
Envafolimab Inhibits the Growth of Gastric Cancer Cells with Low PD-L1 Expression through the DDX20/NF-κB/TNF-α Signaling Pathway., PMID:39021191
DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice., PMID:38657611
DDX20 positively regulates the interferon pathway to inhibit viral infection., PMID:38552910
DDX20: A Multifunctional Complex Protein., PMID:37894677
An artificial neural network model to diagnose non-obstructive azoospermia based on RNA-binding protein-related genes., PMID:37116198
Identification of Genes Involved in EGF-induced Apoptosis Using CRISPR/Cas9 Knockout Screening: Implications for Novel Therapeutic Targets in EGFR-Overexpressing Cancers., PMID:36596724
A Macrophage Differentiation-Mediated Gene: DDX20 as a Molecular Biomarker Encompassing the Tumor Microenvironment, Disease Staging, and Prognoses in Hepatocellular Carcinoma., PMID:36246406
Integration of RNAi and RNA-seq uncovers the regulation mechanism of DDX20 on vitellogenin expression in Scylla paramamosain., PMID:36244220
Genetic Variation in DEAD-Box Helicase 20 as a Putative Marker of Recurrence in Propensity-Matched Colon Cancer Patients., PMID:36011315
Global Phosphoproteomics Analysis of IBRS-2 Cells Infected With Senecavirus A., PMID:35154063
Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression., PMID:34974536
YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44., PMID:34677810
Construction, Identification and Analysis of the Interaction Network of African Swine Fever Virus MGF360-9L with Host Proteins., PMID:34578385
The combined detection of Amphiregulin, Cyclin A1 and DDX20/Gemin3 expression predicts aggressive forms of oral squamous cell carcinoma., PMID:34290392
Ddx20, DEAD box helicase 20, is essential for the differentiation of oligodendrocyte and maintenance of myelin gene expression., PMID:34231259
Human bone mesenchymal stem cells-derived exosomal miRNA-361-5p alleviates osteoarthritis by downregulating DDX20 and inactivating the NF-κB signaling pathway., PMID:34052737
Death-associated protein kinase 1 suppresses hepatocellular carcinoma cell migration and invasion by upregulation of DEAD-box helicase 20., PMID:32449268
SMN complex member Gemin3 self-interacts and has a functional relationship with ALS-linked proteins TDP-43, FUS and Sod1., PMID:31822699
Integrating transcriptome-wide study and mRNA expression profiles yields novel insights into the biological mechanism of chondropathies., PMID:31455417
Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome., PMID:31354704
The multiple lives of DEAD-box RNA helicase DP103/DDX20/Gemin3., PMID:29523774
Analysis of the polymorphic variants of RAN and GEMIN3 genes and risk of Primary Open-Angle Glaucoma in the Polish population., PMID:29095070
Genetic variants of microRNA processing genes and risk of non-syndromic orofacial clefts., PMID:28833944
Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators., PMID:28807014
Regulating the Regulators in Attention-Deficit/Hyperactivity Disorder: A Genetic Association Study of microRNA Biogenesis Pathways., PMID:28557556
Genetic variants in RNA-induced silencing complex genes and prostate cancer., PMID:27498138
Significance of microRNA-related variants in susceptibility to recurrence of oropharyngeal cancer patients after definitive radiotherapy., PMID:27145460
High expression of DDX20 enhances the proliferation and metastatic potential of prostate cancer cells through the NF-κB pathway., PMID:27121695
FOXL2 down-regulates vitellogenin expression at mature stage in Eriocheir sinensis., PMID:26430246
Intracellular Bacterial Pathogens Trigger the Formation of U Small Nuclear RNA Bodies (U Bodies) through Metabolic Stress Induction., PMID:26134566
Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization., PMID:26069323
A Survival Association Study of 102 Polymorphisms Previously Associated with Survival Outcomes in Colorectal Cancer., PMID:26064972
Association of microRNA biogenesis pathway gene variants and alcohol dependence risk., PMID:25495208
DEAD-box helicase DP103 defines metastatic potential of human breast cancers., PMID:25083991
Pseudophosphorylated αB-crystallin is a nuclear chaperone imported into the nucleus with help of the SMN complex., PMID:24023879
FUS-SMN protein interactions link the motor neuron diseases ALS and SMA., PMID:23022481
MicroRNA-140 acts as a liver tumor suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression., PMID:22898998
A miRNA machinery component DDX20 controls NF-κB via microRNA-140 function., PMID:22445758
[Gemin3 inhibits cell apoptosis through suppression of p53 expression]., PMID:22335944
Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosis., PMID:22174681
NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells., PMID:21800163
Comparative structural analysis of human DEAD-box RNA helicases., PMID:20941364
SMN, Gemin2 and Gemin3 associate with beta-actin mRNA in the cytoplasm of neuronal cells in vitro., PMID:20620147
Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein., PMID:20510246
Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3)., PMID:20157854
The DEAD-box protein MEL-46 is required in the germ line of the nematode Caenorhabditis elegans., PMID:19534797
A motor function for the DEAD-box RNA helicase, Gemin3, in Drosophila., PMID:19023405
For research use only. Not for human or drug use.
