Catalog No.
YHK13001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser87-Asp319
Predicted molecular weight
28.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H1D0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CaT1, Transient receptor potential cation channel subfamily V member 6, CaT-like, TrpV6, CaT-L, ECAC2, TRPV6, ECaC2, Epithelial calcium channel 2, Calcium transport protein 1
Estrogen regulates duodenal calcium absorption and improves postmenopausal osteoporosis by the effect of ERβ on PMCA1b., PMID:40341576
Unlocking the potential of Bavachin in vitamin D receptor cascade modulation for rheumatoid arthritis., PMID:40285969
Regulatory Role of Oxytocin in Ionocyte Functions During Zebrafish Cold Acclimation., PMID:40277309
The characterization of uterine calcium transport and metabolism during eggshell calcification of hens laying high or low breaking strength eggshell., PMID:40222347
Subchronic Exposure to Polystyrene Nanoplastics Disrupts Placental Development and Calcium Homeostasis: Insights from In Vivo and In Vitro Models., PMID:40171975
Partial renal deletion of Klotho is not sufficient to impact renal electrolyte handling in distal convoluted tubule specific knock-out mice., PMID:40165603
The impact of inducible-whole body or intestine-specific Cyp24a1 gene knockout on vitamin D metabolism in mice., PMID:40096918
Gene expression of calcium transporters Calbindin-D28K and TRPV6 in Japanese quails (Coturnix japonica) subjected to phytase super-dosing and under different temperatures., PMID:40010049
Long-term excessive salt consumption alters villous and crypt morphology and the protein expression of uroguanylin, TRPV6 and PMCA1b in the rat small intestine., PMID:39820616
The Molecular Biology of Placental Transport of Calcium to the Human Foetus., PMID:39796238
Sox10 is required for systemic initiation of bone mineralization., PMID:39791977
Overexpression of TRPV6 Inhibits Coronary Atherosclerosis-Related Inflammatory Response and Cell Apoptosis via the PKA/UCP2 Pathway., PMID:39742020
The potential of TRP channels as new prognostic and therapeutic targets against prostate cancer progression., PMID:39586480
Structure-function analyses of human TRPV6 ancestral and derived haplotypes., PMID:39500315
The endocannabinoid system in bovine tissues: characterization of transcript abundance in the growing Holstein steer., PMID:39438841
Renal expression of calcium and phosphorus transporters: contrasting responses to dietary calcium and microbial phytase in broilers and growing pigs., PMID:39417344
Analysis of Differential Gene Expression under Acute Lead or Mercury Exposure in Larval Zebrafish Using RNA-Seq., PMID:39409826
TRPV6 gene mutation associated with giant pancreatic pseudocyst with mediastinal extension in a pediatric patient: Lessons learned., PMID:39266467
Impact of Lactobacillus acidophilus and Its Combination with Isoflavone Products on Calcium Status, Calcium Transporters, and Bone Metabolism Biomarkers in a Post-Menopausal Osteoporotic Rat Model., PMID:39125403
Fibroblast growth factor-21 potentiates the stimulatory effects of 1,25-dihydroxyvitamin D3 on transepithelial calcium transport and TRPV6 Ca2+ channel expression., PMID:39053106
Curcumin ameliorates pyroptosis in diabetic seminal vesicles by upregulating TRPV6., PMID:38966878
Trpv6 channel targeting using monoclonal antibody induces prostate cancer cell apoptosis and tumor regression., PMID:38879621
Lactobacillus helveticus-Derived Whey-Calcium Chelate Promotes Calcium Absorption and Bone Health of Rats Fed a Low-Calcium Diet., PMID:38674818
Diagnostic yield of repeat genetic testing in idiopathic chronic pancreatitis., PMID:38657903
Advances in TRPV6 inhibitors for tumors by targeted therapies: Macromolecular proteins, synthetic small molecule compounds, and natural compounds., PMID:38588625
Naringenin Alleviates Radiation-Induced Intestinal Injury by Inhibiting TRPV6 in Mice., PMID:38581304
Characterization and Mechanism of a Novel Rice Protein Peptide (AHVGMSGEEPE) Calcium Chelate in Enhancing Calcium Absorption in Caco-2 Cells., PMID:38563891
The TRPV6 Calcium Channel and Its Relationship with Cancer., PMID:38534438
Ruthenium red: Blocker or antagonist of TRPV channels?, PMID:38518427
Male Lrp5A214V mice maintain high bone mass during dietary calcium restriction by altering the vitamin D endocrine system., PMID:38477773
Relationship of the bone phenotype of the Klotho mutant mouse model of accelerated aging to changes in skeletal architecture that occur with chronological aging., PMID:38352710
Vitamin D, Calbindin, and calcium signaling: Unraveling the Alzheimer's connection., PMID:38211841
Bidirectional Allosteric Coupling between PIP2 Binding and the Pore of the Oncochannel TRPV6., PMID:38203789
Transcriptomic profile of the mechanosensitive ion channelome in human cardiac fibroblasts., PMID:38158807
Enhancement of intestinal calcium transport by short-chain fatty acids: roles of Na+/H+ exchanger 3 and transient receptor potential vanilloid subfamily 6., PMID:38073487
Molecular Similarity for Drug Discovery, Target Prediction and Chemical Space Visualization., PMID:38069801
Stanniocalcin 1a regulates organismal calcium balance and survival by suppressing Trpv6 expression and inhibiting IGF signaling in zebrafish., PMID:37964974
Transient Receptor Potential Vanilloid 6 Modulates Aberrant Axonal Sprouting in a Mouse Model of Pilocarpine-Induced Epilepsy., PMID:37940780
Probing Conformational Transition of TRPV5 Induced by Mechanical Force Using Coarse-Grained Molecular Dynamics., PMID:37871325
Phosphoinositide Regulation of TRP Channels: A Functional Overview in the Structural Era., PMID:37871124
Mechanism of Lactiplantibacillus plantarum regulating Ca2+ affecting the replication of PEDV in small intestinal epithelial cells., PMID:37840713
Molecular pharmacology of the onco-TRP channel TRPV6., PMID:37838981
Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A., PMID:37735536
Calcium binding and permeation in TRPV channels: Insights from molecular dynamics simulations., PMID:37728593
Methotrexate Chemotherapy Causes Growth Impairments, Vitamin D Deficiency, Bone Loss, and Altered Intestinal Metabolism-Effects of Calcitriol Supplementation., PMID:37686643
Adhesion GPCR Gpr126 (Adgrg6) Expression Profiling in Zebrafish, Mouse, and Human Kidney., PMID:37566066
PDIA3 modulates genomic response to 1,25-dihydroxyvitamin D3 in squamous cell carcinoma of the skin., PMID:37549780
Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin., PMID:37532722
The role of cadmium in the pathogenesis of myeloid leukemia in individuals with anemia, deficiencies in vitamin D, zinc, and low calcium dietary intake., PMID:37499549
Purification, Identification, Chelation Mechanism, and Calcium Absorption Activity of a Novel Calcium-Binding Peptide from Peanut (Arachis hypogaea) Protein Hydrolysate., PMID:37493196
For research use only. Not for human or drug use.
