Catalog No.
YHK66701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly72-Arg152
Predicted molecular weight
21.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y5S9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ribonucleoprotein RBM8A, RNA-binding protein Y14, RNA-binding motif protein 8A, BOV-1, RBM8A, Binder of OVCA1-1, RBM8, RNA-binding protein 8A
hsa_circ_0081343 interacts with Rbm8a to inhibit NLRP3-mediated pyroptosis via the PI3K/AKT/HIF-1α pathways., PMID:40267529
PYM1 limits non-canonical Exon Junction Complex occupancy in a gene architecture dependent manner to tune mRNA expression., PMID:40161626
Circular RNA hsa_circ_0081343 modulates trophoblast autophagy through Rbm8a nuclear translocation., PMID:39413593
Whole Exome Sequencing Identifies Epithelial and Immune Dysfunction-Related Biomarkers in Food Protein-Induced Enterocolitis Syndrome., PMID:39348862
RBM8A, a new target of TEAD4, promotes breast cancer progression by regulating IGF1R and IRS-2., PMID:39232805
The Exon Junction Complex Factor RBM8A in Glial Fibrillary Acid Protein-Expressing Astrocytes Modulates Locomotion Behaviors., PMID:38534343
Determination of Carrier Frequency of Actionable Pathogenic Variants in Autosomal Recessive Genetic Diseases in the Turkish Cypriot Population., PMID:37895316
Rbm8a regulates neurogenesis and reduces Alzheimer's disease-associated pathology in the dentate gyrus of 5×FAD mice., PMID:37843222
Clinical exome sequencing efficacy and phenotypic expansions involving anomalous pulmonary venous return., PMID:37673932
Comprehensive bioinformatics analysis of a RBM family-based prognostic signature with experiment validation in hepatocellular carcinoma., PMID:37410140
Co-phase separation of Y14 and RNA in vitro and its implication for DNA repair., PMID:37001915
Transcriptomic Analyses of Brains of RBM8A Conditional Knockout Mice at Different Developmental Stages Reveal Conserved Signaling Pathways Contributing to Neurodevelopmental Diseases., PMID:36902031
Weighted gene co-expression network analysis reveals the hub genes associated with pulmonary hypertension., PMID:36740764
Comprehensive transcriptomics and proteomics analysis of Carassius auratus gills in response to Aeromonas hydrophila., PMID:36589261
Multifaceted roles of MAGOH Proteins., PMID:36396768
Erratum: The glycolytic enzyme ALDOA and the exon junction complex protein RBM8A are regulators of ribosomal biogenesis., PMID:36393862
The glycolytic enzyme ALDOA and the exon junction complex protein RBM8A are regulators of ribosomal biogenesis., PMID:36187487
Diverse Roles of the Exon Junction Complex Factors in the Cell Cycle, Cancer, and Neurodevelopmental Disorders-Potential for Therapeutic Targeting., PMID:36142288
RBM8A Depletion Decreases the Cisplatin Resistance and Represses the Proliferation and Metastasis of Breast Cancer Cells via AKT/mTOR Pathway., PMID:36105365
Thrombocytopenia-Absent Radius Syndrome: Descriptions of Three New Cases and a Novel Splicing Variant in RBM8A That Expands the Spectrum of Null Alleles., PMID:36077017
Integrated Bioinformatics Analysis of the Hub Genes Involved in Irinotecan Resistance in Colorectal Cancer., PMID:35885025
Corrigendum: Isobaric Tags for Relative and Absolute Quantitation Identification of Blood Proteins Relevant to Paroxetine Response in Patients With Major Depressive Disorder., PMID:35873247
Isobaric Tags for Relative and Absolute Quantitation Identification of Blood Proteins Relevant to Paroxetine Response in Patients With Major Depressive Disorder., PMID:35509884
The Physiological Roles of the Exon Junction Complex in Development and Diseases., PMID:35406756
Influence of verapamil on pressure overload-induced ventricular arrhythmias by regulating gene-expression profiles., PMID:35315872
Double-Stranded RNA Structural Elements Holding the Key to Translational Regulation in Cancer: The Case of Editing in RNA-Binding Motif Protein 8A., PMID:34944051
RBM8A Promotes Glioblastoma Growth and Invasion Through the Notch/STAT3 Pathway., PMID:34804926
A Comprehensive Pan-Cancer Analysis of RBM8A Based on Data Mining., PMID:34326876
The Exon Junction Complex Core Represses Cancer-Specific Mature mRNA Re-splicing: A Potential Key Role in Terminating Splicing., PMID:34204574
Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis., PMID:33649372
Mechanism and Molecular Network of RBM8A-Mediated Regulation of Oxaliplatin Resistance in Hepatocellular Carcinoma., PMID:33552961
Full function of exon junction complex factor, Rbm8a, is critical for interneuron development., PMID:33154347
T-Cell Acute Lymphoblastic Leukemia in a Young Adult With Thrombocytopenia-absent Radius Syndrome: A Case Report and Review of the Literature., PMID:32815886
Identification of Target Genes in Hypertension and Left Ventricular Remodeling., PMID:32664164
Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3'UTR intron-containing NMD targets., PMID:32502192
Prognostic value of increased expression of RBM8A in gastric cancer., PMID:32294703
TAR syndrome: Clinical and molecular characterization of a cohort of 26 patients and description of novel noncoding variants of RBM8A., PMID:32227665
Expanding the phenotype of thrombocytopenia absent radius syndrome with hypospadias., PMID:32109542
1q21.1 deletion and a rare functional polymorphism in siblings with thrombocytopenia-absent radius-like phenotypes., PMID:31836590
Identification of molecular correlations of RBM8A with autophagy in Alzheimer's disease., PMID:31816601
PPWD1 is associated with the occurrence of postmenopausal osteoporosis as determined by weighted gene co‑expression network analysis., PMID:31432133
Identification of antiviral roles for the exon-junction complex and nonsense-mediated decay in flaviviral infection., PMID:30833725
The stability of Magoh and Y14 depends on their heterodimer formation and nuclear localization., PMID:30826064
An eight-case 1q21 region series: novel aberrations and clinical variability with new features., PMID:30773728
Expression and gene regulation network of RBM8A in hepatocellular carcinoma based on data mining., PMID:30670676
Immuno-detection of mRNA-binding protein complex in human cells under transmission electron microscopy., PMID:30637830
Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity., PMID:30388410
Glycogen synthase kinase-3 and alternative splicing., PMID:30118183
SOX9 has distinct regulatory roles in alternative splicing and transcription., PMID:29901772
For research use only. Not for human or drug use.
