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Recombinant Human RAD51AP1 Protein, N-His-SUMO

Catalog #:   YHK66601 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q96B01
Protein length: Arg70-Asn116
Overview

Catalog No.

YHK66601

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Arg70-Asn116

Predicted molecular weight

17.45 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q96B01

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

PIR51, RAD51-interacting protein, RAD51-associated protein 1, RAD51AP1, HsRAD51AP1

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human RAD51AP1 Protein
References

Transcriptomic analysis of laser-capture microdissected tumors reveals RAD51AP1 as a tumor-specific marker associated progression from pancreatic intraepithelial neoplasia to invasive pancreatic cancer., PMID:40495122

Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributing to temozolomide resistance in EGFRvIII glioblastoma., PMID:40211735

A Dual-Targeted Molecule for Disease-Activatable Proteolysis Targeting Chimeras and Targeted Radionuclide Therapy of Cancer., PMID:39989465

Biomarker Panels Associated with Diagnosis and Overall Survival in Hepatocellular Carcinoma Revealed from Protein-Protein and mRNA-miRNA Interaction Networks., PMID:39874008

Identification of RAD51AP1 as a key gene in hepatitis B virus-associated hepatocellular carcinoma., PMID:39850418

Knocking down RAD51AP1 enhances chemosensitivity by inhibiting the self-renewal of CD133 positive ovarian cancer stem-like cells., PMID:39235706

SUMO promotes DNA repair protein collaboration to support alternative telomere lengthening in the absence of PML., PMID:39038850

DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces., PMID:38828772

[Auxiliary diagnosis and prognosis evaluation of KIF4A, RAD51AP1 and CDKN3 in esophageal cancer]., PMID:38715507

SUMO Promotes DNA Repair Protein Collaboration to Support Alterative Telomere Lengthening in the Absence of PML., PMID:38463993

TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells., PMID:38461301

Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks., PMID:38403248

PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer., PMID:38353332

[Research Advances of RAD51AP1 in Tumor Progression and Drug Resistance]., PMID:37985156

The gene RAD51AP1 promotes the progression of pancreatic cancer via the PI3K/Akt/NF-κB signaling pathway., PMID:37962862

E2F7/RAD51AP1 Axis Inhibits Endometrial Cancer Sensitivity to 5-FU via the Fatty Acid Metabolic Pathway., PMID:37909953

Transcriptome analysis of meiotic and post-meiotic spermatogenic cells reveals the potential hub genes of aging on the decline of male fertility., PMID:37839768

Advanced stage, high-grade primary tumor ovarian cancer: a multi-omics dissection and biomarker prediction process., PMID:37828118

RAD51AP1 as an Immune-Related Prognostic Biomarker and Therapeutic Response Predictor in Hepatocellular Carcinoma., PMID:37789880

Life span-associated ferroptosis-related genes identification and validation for hepatocellular carcinoma patients as hepatitis B virus carriers., PMID:37461802

PTBP1 enforces ATR-CHK1 signaling determining the potency of CDC7 inhibitors., PMID:37378325

Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?, PMID:37306551

Identification of the E2F1-RAD51AP1 axis as a key factor in MGMT-methylated GBM TMZ resistance., PMID:37283490

High expression of KIF20A in bladder cancer as a potential prognostic target for poor survival of renal cell carcinoma., PMID:36637953

Systematic pan-cancer analysis showed that RAD51AP1 was associated with immune microenvironment, tumor stemness, and prognosis., PMID:36468013

TERRA and RAD51AP1 at the R&D-loop department of ALT telomeres., PMID:36332602

RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA., PMID:36265488

TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch., PMID:36265486

Knockdown of RAD51AP1 suppressed cell proliferation and invasion in esophageal squamous cell carcinoma., PMID:36197550

METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma., PMID:35856434

RAD51AP1 and RAD54L Can Underpin Two Distinct RAD51-Dependent Routes of DNA Damage Repair via Homologous Recombination., PMID:35652094

NUSAP1 Could be a Potential Target for Preventing NAFLD Progression to Liver Cancer., PMID:35431924

Integrated bioinformatics analysis of potential biomarkers for pancreatic cancer., PMID:35403252

Identification of 9 Gene Signatures by WGCNA to Predict Prognosis for Colon Adenocarcinoma., PMID:35392038

Differential Expression of RAD51AP1 in Ovarian Cancer: Effects of siRNA In Vitro., PMID:35207688

Identifying key genes and screening therapeutic agents associated with diabetes mellitus and HCV-related hepatocellular carcinoma by bioinformatics analysis., PMID:34588861

RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy., PMID:34099522

ZEB1 induces non-small cell lung cancer development by targeting microRNA-320a to increase the expression of RAD51AP1., PMID:34097859

RAD51AP1 mediates RAD51 activity through nucleosome interaction., PMID:34058198

RNA transcripts stimulate homologous recombination by forming DR-loops., PMID:33981036

BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair., PMID:33712705

Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCR., PMID:33403046

RAD51AP1 promotes progression of ovarian cancer via TGF-β/Smad signalling pathway., PMID:33314567

Oncogenic Roles of RAD51AP1 in Tumor Tissues Related to Overall Survival and Disease-Free Survival in Hepatocellular Carcinoma., PMID:33269607

A Novel Neoplastic Fusion Transcript, RAD51AP1-DYRK4, Confers Sensitivity to the MEK Inhibitor Trametinib in Aggressive Breast Cancers., PMID:33172895

Identification of unique long non-coding RNAs as putative biomarkers for chromophobe renal cell carcinoma., PMID:33052074

The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis., PMID:32978522

Identification of hub genes associated with esophageal cancer progression using bioinformatics analysis., PMID:32963620

NUCKS1 promotes RAD54 activity in homologous recombination DNA repair., PMID:32876692

RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal., PMID:32665355

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human RAD51AP1 Protein, N-His-SUMO [YHK66601]
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