Catalog No.
YHK66601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg70-Asn116
Predicted molecular weight
17.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96B01
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PIR51, RAD51-interacting protein, RAD51-associated protein 1, RAD51AP1, HsRAD51AP1
Transcriptomic analysis of laser-capture microdissected tumors reveals RAD51AP1 as a tumor-specific marker associated progression from pancreatic intraepithelial neoplasia to invasive pancreatic cancer., PMID:40495122
Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributing to temozolomide resistance in EGFRvIII glioblastoma., PMID:40211735
A Dual-Targeted Molecule for Disease-Activatable Proteolysis Targeting Chimeras and Targeted Radionuclide Therapy of Cancer., PMID:39989465
Biomarker Panels Associated with Diagnosis and Overall Survival in Hepatocellular Carcinoma Revealed from Protein-Protein and mRNA-miRNA Interaction Networks., PMID:39874008
Identification of RAD51AP1 as a key gene in hepatitis B virus-associated hepatocellular carcinoma., PMID:39850418
Knocking down RAD51AP1 enhances chemosensitivity by inhibiting the self-renewal of CD133 positive ovarian cancer stem-like cells., PMID:39235706
SUMO promotes DNA repair protein collaboration to support alternative telomere lengthening in the absence of PML., PMID:39038850
DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces., PMID:38828772
[Auxiliary diagnosis and prognosis evaluation of KIF4A, RAD51AP1 and CDKN3 in esophageal cancer]., PMID:38715507
SUMO Promotes DNA Repair Protein Collaboration to Support Alterative Telomere Lengthening in the Absence of PML., PMID:38463993
TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells., PMID:38461301
Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks., PMID:38403248
PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer., PMID:38353332
[Research Advances of RAD51AP1 in Tumor Progression and Drug Resistance]., PMID:37985156
The gene RAD51AP1 promotes the progression of pancreatic cancer via the PI3K/Akt/NF-κB signaling pathway., PMID:37962862
E2F7/RAD51AP1 Axis Inhibits Endometrial Cancer Sensitivity to 5-FU via the Fatty Acid Metabolic Pathway., PMID:37909953
Transcriptome analysis of meiotic and post-meiotic spermatogenic cells reveals the potential hub genes of aging on the decline of male fertility., PMID:37839768
Advanced stage, high-grade primary tumor ovarian cancer: a multi-omics dissection and biomarker prediction process., PMID:37828118
RAD51AP1 as an Immune-Related Prognostic Biomarker and Therapeutic Response Predictor in Hepatocellular Carcinoma., PMID:37789880
Life span-associated ferroptosis-related genes identification and validation for hepatocellular carcinoma patients as hepatitis B virus carriers., PMID:37461802
PTBP1 enforces ATR-CHK1 signaling determining the potency of CDC7 inhibitors., PMID:37378325
Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?, PMID:37306551
Identification of the E2F1-RAD51AP1 axis as a key factor in MGMT-methylated GBM TMZ resistance., PMID:37283490
High expression of KIF20A in bladder cancer as a potential prognostic target for poor survival of renal cell carcinoma., PMID:36637953
Systematic pan-cancer analysis showed that RAD51AP1 was associated with immune microenvironment, tumor stemness, and prognosis., PMID:36468013
TERRA and RAD51AP1 at the R&D-loop department of ALT telomeres., PMID:36332602
RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA., PMID:36265488
TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch., PMID:36265486
Knockdown of RAD51AP1 suppressed cell proliferation and invasion in esophageal squamous cell carcinoma., PMID:36197550
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma., PMID:35856434
RAD51AP1 and RAD54L Can Underpin Two Distinct RAD51-Dependent Routes of DNA Damage Repair via Homologous Recombination., PMID:35652094
NUSAP1 Could be a Potential Target for Preventing NAFLD Progression to Liver Cancer., PMID:35431924
Integrated bioinformatics analysis of potential biomarkers for pancreatic cancer., PMID:35403252
Identification of 9 Gene Signatures by WGCNA to Predict Prognosis for Colon Adenocarcinoma., PMID:35392038
Differential Expression of RAD51AP1 in Ovarian Cancer: Effects of siRNA In Vitro., PMID:35207688
Identifying key genes and screening therapeutic agents associated with diabetes mellitus and HCV-related hepatocellular carcinoma by bioinformatics analysis., PMID:34588861
RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy., PMID:34099522
ZEB1 induces non-small cell lung cancer development by targeting microRNA-320a to increase the expression of RAD51AP1., PMID:34097859
RAD51AP1 mediates RAD51 activity through nucleosome interaction., PMID:34058198
RNA transcripts stimulate homologous recombination by forming DR-loops., PMID:33981036
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair., PMID:33712705
Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCR., PMID:33403046
RAD51AP1 promotes progression of ovarian cancer via TGF-β/Smad signalling pathway., PMID:33314567
Oncogenic Roles of RAD51AP1 in Tumor Tissues Related to Overall Survival and Disease-Free Survival in Hepatocellular Carcinoma., PMID:33269607
A Novel Neoplastic Fusion Transcript, RAD51AP1-DYRK4, Confers Sensitivity to the MEK Inhibitor Trametinib in Aggressive Breast Cancers., PMID:33172895
Identification of unique long non-coding RNAs as putative biomarkers for chromophobe renal cell carcinoma., PMID:33052074
The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis., PMID:32978522
Identification of hub genes associated with esophageal cancer progression using bioinformatics analysis., PMID:32963620
NUCKS1 promotes RAD54 activity in homologous recombination DNA repair., PMID:32876692
RAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal., PMID:32665355