Catalog No.
YHK66501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser388
Predicted molecular weight
44.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HCU5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PREB, Prolactin regulatory element-binding protein, Mammalian guanine nucleotide exchange factor mSec12, SEC12
Insights from the bottom-up development of LGR5-targeting immunotherapeutics., PMID:40405910
Methyltransferase-like 16 drives diabetic nephropathy progression via epigenetic suppression of V-set pre-B cell surrogate light chain 3., PMID:40348175
Activation of Neutrophil Extracellular Trap Formation in Patients with Heart Failure and a Preserved Ejection Fraction., PMID:40081731
siRNA-mediated inhibition of hTERT enhances the effects of curcumin in promoting cell death in precursor-B acute lymphoblastic leukemia cells: an in silico and in vitro study., PMID:39856130
Glucocorticoid signaling mediates lymphopoiesis impairment after cardiac arrest in mice., PMID:39835422
Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages., PMID:39775457
STAT1 Promotes PD-L1 Activation and Tumor Growth in Lymphangioleiomyomatosis., PMID:39713456
Extracellular vesicles released by ALL patients contain HNE-adducted proteins: Implications of collateral damage., PMID:39643137
Effects of prebiotic and multispecies probiotic supplementation on the gut microbiota, immune function, and growth performance of weaned piglets., PMID:39570882
DNA damage-induced p53 downregulates expression of RAG1 through a negative feedback loop involving miR-34a and FOXP1., PMID:39454960
Conserved helical motifs in the IKZF1 disordered region mediate NuRD interaction and transcriptional repression., PMID:39437550
Mycovirus-Containing Aspergillus flavus Alters Transcription Factors in Normal and Acute Lymphoblastic Leukemia Cells., PMID:39408690
Integrated multi-omics analysis of PBX1 in mouse adult neural stem- and progenitor cells identifies a transcriptional module that functionally links PBX1 to TCF3/4., PMID:39377397
Profiling the impact of anti-human CD20 monoclonal antibodies on lymphocyte B cell subsets and their precursors in the bone marrow and in lymphoid tissues in an immunocompromised mouse engrafted with human cells., PMID:39374887
Negative regulation of activation-induced cytidine deaminase gene transcription in developing B cells by a PU.1-interacting intronic region., PMID:39332244
The chemokine receptor CCR8 is not a high-affinity receptor for the human chemokine CCL18., PMID:39259753
Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development., PMID:39179932
An Optimized Peptide Antagonist of CXCR4 Limits Survival of BCR-ABL1-Transformed Cells in Philadelphia-Chromosome-Positive B-Cell Acute Lymphoblastic Leukemia., PMID:39125877
The Kinetics of Inflammation-Related Proteins and Cytokines in Children Undergoing CAR-T Cell Therapy-Are They Biomarkers of Therapy-Related Toxicities?, PMID:39062195
Pre-B cell receptor acts as a selectivity switch for galectin-1 at the pre-B cell surface., PMID:39058594
RAG1/2 induces double-stranded DNA breaks at non-Ig loci in the proximity of single sequence repeats in developing B cells., PMID:39046890
A pre-B acute lymphoblastic leukemia cell line model reveals the mechanism of thalidomide therapy-related B-cell leukemogenesis., PMID:39029626
Results of the Simultaneous Combination of Ponatinib and Blinatumomab in Philadelphia Chromosome-Positive ALL., PMID:39028925
ATM-dependent Phosphorylation of Nemo SQ Motifs Is Dispensable for Nemo-mediated Gene Expression Changes in Response to DNA Double-Strand Breaks., PMID:39007641
YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment., PMID:38990722
Technological and sensory characteristics in development of innovative symbiotic boneless dry-cured lamb meat snack., PMID:38917677
Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia., PMID:38822412
Fluoxetine Successfully Treats Intracranial Enterovirus E18 Infection in a Patient with CD79a Deficiency Arising from Segmental Uniparental Disomy of Chromosome 19., PMID:38805163
Structural insights into the cross-exon to cross-intron spliceosome switch., PMID:38778104
Clinical and Immunologic Features of a Patient With Homozygous FNIP1 Variant., PMID:38748614
SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23., PMID:38743621
Triple Trouble., PMID:38736127
Structural insights into human exon-defined spliceosome prior to activation., PMID:38658629
Lupus susceptibility gene Pbx1 controls the development, stability, and function of regulatory T cells via Rtkn2 expression., PMID:38536923
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL., PMID:38512136
Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome., PMID:38484052
A role for SNU66 in maintaining 5' splice site identity during spliceosome assembly., PMID:38443114
PBX1: a TALE of two seasons-key roles during development and in cancer., PMID:38404687
Targeting TNF/IL-17/MAPK pathway in hE2A-PBX1 leukemia: effects of OUL35, KJ-Pyr-9, and CID44216842., PMID:38385270
Single-cell analysis with childhood and adult systemic lupus erythematosus., PMID:38347676
IN-DEPTH MAPPING OF DNA-PKcs SIGNALING UNCOVERS CONSERVED FEATURES OF ITS KINASE SPECIFICITY., PMID:38293078
Influence of pre-B cell receptor deficiency on the immunoglobulin repertoires in peripheral blood B cells before and after immunization., PMID:38271880
Combinatorial targeting of telomerase and DNA-PK induces synergistic apoptotic effects against Pre-B acute lymphoblastic leukemia cells., PMID:38252348
Landscape of protein-protein interactions during hepatitis C virus assembly and release., PMID:38230952
Transcription factor PBX4 regulates limb development and haematopoiesis in mice., PMID:38230761
IKZF3/Aiolos H195Y mutation identified in a mouse model of B cell leukemia results in altered DNA binding and altered STAT5-dependent gene expression., PMID:38216003
Molecular-genetic pathways of hepatitis C virus regulation of the expression of cellular factors PREB and PLA2G4C, which play an important role in virus replication., PMID:38213698
Relapses in early-stage follicular lymphoma frequently develop via a divergent evolution from their clonally related precursor cells., PMID:38156368
Association of Visfatin gene polymorphism with obesity related metabolic disorders among Pakistani population: a case control study., PMID:38155161
Constitutively active CaMKII Drives B lineage acute lymphoblastic leukemia/lymphoma in tp53 mutant zebrafish., PMID:38117861
For research use only. Not for human or drug use.
